World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
43
Citations
8676
World Ranking
17098
National Ranking
4207

Overview

Michael J. Chalmers is affiliated with Eli Lilly in the United States and has contributed research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans subfields including Molecular Biology, Endocrinology, Diabetes and Metabolism, Immunology, Surgery, and Spectroscopy.

The scientist's research topics cover Diabetes Treatment and Management, Pancreatic function and diabetes, Protein Kinase Regulation and GTPase Signaling, Microbial Natural Products and Biosynthesis, Melanoma and MAPK Pathways, Macrophage Migration Inhibitory Factor, and NF-κB Signaling Pathways.

Recent papers authored or co-authored by Michael J. Chalmers include:

  • Abstract 1259: Preclinical characterization of LY3537982, a novel, highly selective and potent KRAS-G12C inhibitor (2021), Cancer Research
  • Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages (2024), Cell Reports
  • SHIP1 modulation and proteome characterization of microglia (2024), Journal of Proteomics
  • Differential Role of Phosphorylation in Glucagon Family Receptor Signaling Revealed by Mass Spectrometry (2025), Journal of Proteome Research
  • SHIP1 modulation and proteome characterization of microglia (2023), bioRxiv (Cold Spring Harbor Laboratory)

Michael J. Chalmers has frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Cell Reports
  • Journal of Proteomics
  • Journal of Proteome Research

Collaboration has been an important aspect of their research, with frequent co-authors including:

  • Junpeng Xiao
  • Kenneth D. Roth
  • Jesus A. Gutierrez
  • Ian M. Lamb
  • Alex D. White

Best Publications

  • Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

    Jang Hyun Choi;Alexander S. Banks;Jennifer L. Estall;Shingo Kajimura

  • Molecular Mimicry Regulates ABA Signaling by SnRK2 Kinases and PP2C Phosphatases

    Fen Fen Soon;Fen Fen Soon;Ley Moy Ng;Ley Moy Ng;X. Edward Zhou;Graham M. West

  • Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

    Jang Hyun Choi;Alexander S. Banks;Theodore M. Kamenecka;Scott A. Busby

  • Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism

    John B. Bruning;Michael J. Chalmers;Swati Prasad;Scott A. Busby

  • Probing Protein Ligand Interactions by Automated Hydrogen/Deuterium Exchange Mass Spectrometry

    Michael J Chalmers;Scott A Busby;Bruce D Pascal;Yuanjun He

  • HDX workbench: software for the analysis of H/D exchange MS data.

    Bruce D. Pascal;Scooter Willis;Janelle L. Lauer;Rachelle R. Landgraf

  • Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions

    Michael J Chalmers;Scott A Busby;Bruce D Pascal;Graham M West

  • Combined electron capture and infrared multiphoton dissociation for multistage MS/MS in a Fourier transform ion cyclotron resonance mass spectrometer.

    Kristina Håkansson;Michael J. Chalmers;John P. Quinn;Melinda A. McFarland

  • DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

    Jun Zhang;Michael J Chalmers;Keith R Stayrook;Lorri L Burris

  • Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands

    Yongjun Wang;Naresh Kumar;Laura A. Solt;Timothy I. Richardson

  • Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.

    L.M Ng;F.F Soon;F.F Soon;X.E Zhou;G.M West

  • Ligand and Receptor Dynamics Contribute to the Mechanism of Graded PPARγ Agonism

    Travis S. Hughes;Michael J. Chalmers;Scott Novick;Dana S. Kuruvilla

  • Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors

    Raghu R. V. Malapaka;Sok Kean Khoo;Jifeng Zhang;Jang Hyun Choi

  • Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Revealed by HDX

    Graham M. West;Ellen Y.T. Chien;Vsevolod Katritch;Jovylyn Gatchalian

  • Identification of Mycobacterium tuberculosis H37Rv Integral Membrane Proteins by One-Dimensional Gel Electrophoresis and Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

    Ying Xiong;Michael J. Chalmers;Fei Philip Gao;Timothy A. Cross,§,‖ and

  • Dynamics of the β2-Adrenergic G-Protein Coupled Receptor Revealed by Hydrogen−Deuterium Exchange

    Xi Zhang;Ellen Y. T. Chien;Michael J. Chalmers;Bruce D. Pascal

  • Advances in mass spectrometry for proteome analysis.

    Michael J Chalmers;Simon J Gaskell

  • Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

    Douglas J. Kojetin;Edna Matta-Camacho;Travis S. Hughes;Sathish Srinivasan

  • Characterization of Tetrahymena Histone H2B Variants and Posttranslational Populations by Electron Capture Dissociation (ECD) Fourier Transform Ion Cyclotron Mass Spectrometry (FT-ICR MS)

    K.F. Medzihradszky;X. Zhang;R.J. Chalkley;S. Guan

  • HD desktop: An integrated platform for the analysis and visualization of H/D exchange data

    Bruce D. Pascal;Michael J. Chalmers;Scott A. Busby;Patrick R. Griffin

Frequent Co-Authors

Patrick R. Griffin
Patrick R. Griffin Scripps Research Institute
Alan G. Marshall
Alan G. Marshall Florida State University
Christopher L. Hendrickson
Christopher L. Hendrickson Florida State University
Thomas P. Burris
Thomas P. Burris Washington University in St. Louis
H. Eric Xu
H. Eric Xu Chinese Academy of Sciences
Harald Mischak
Harald Mischak University of Glasgow
Simon J. Gaskell
Simon J. Gaskell Plymouth University
Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Naresh Kumar
Naresh Kumar University of New South Wales
Jun Li
Jun Li Xi'an Jiaotong University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens up diverse career opportunities beyond traditional laboratory roles. Many students explore related fields that leverage their scientific knowledge. For example, an online associate degree in a different discipline like criminal justice can provide flexible career options. To explore this, check out the best online criminal justice associate degree programs available.

Alternatively, science graduates might consider paralegal work focusing on patent law or healthcare. Understanding the types of paralegals and their salary prospects can help target the right education path. This offers a unique blend of legal and scientific expertise.

Pharmaceutical sales is another common career pathway for Chemistry majors. Gaining knowledge about how to enter this field is essential. Learn more about how to get into pharmaceutical sales, including the skills needed and expected salary ranges.

If your interest lies in healthcare, becoming a pharmacist is a rewarding but challenging option. It requires rigorous training and dedication. Explore the realities and requirements of this profession by reading on is it hard to become a pharmacist.

Best Scientists Citing Michael J. Chalmers

Trending Scientists