D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 75 Citations 17,060 202 World Ranking 3388 National Ranking 1740

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Transcription factor

Thomas P. Burris focuses on Nuclear receptor, Receptor, Biochemistry, Cell biology and Endocrinology. His Nuclear receptor study combines topics in areas such as Oxysterol, Cellular differentiation and Cancer research. His Receptor research is multidisciplinary, incorporating elements of RAR-related orphan receptor alpha, Transcription factor, Estrogen receptor and Pharmacology.

Thomas P. Burris has researched Transcription factor in several fields, including Molecular biology, Psychological repression and ARNTL. The Cell biology study combines topics in areas such as Peroxisome proliferator-activated receptor and Autoimmune disease. The Endocrinology study which covers Internal medicine that intersects with Adrenal hypoplasia.

His most cited work include:

  • Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA (556 citations)
  • Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists (459 citations)
  • Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ (405 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Nuclear receptor, Receptor, Internal medicine, Endocrinology and Cell biology. His Nuclear receptor research incorporates elements of Agonist and Retinoic acid. He focuses mostly in the field of Agonist, narrowing it down to matters related to Stereochemistry and, in some cases, Plasma protein binding.

The various areas that Thomas P. Burris examines in his Receptor study include RAR-related orphan receptor alpha, Immune system, Retinoic acid receptor, Farnesoid X receptor and Pharmacology. His study focuses on the intersection of Cell biology and fields such as RAR-related orphan receptor gamma with connections in the field of Interleukin 17. In his study, Warburg effect is inextricably linked to Inverse agonist, which falls within the broad field of Liver X receptor.

He most often published in these fields:

  • Nuclear receptor (46.98%)
  • Receptor (32.56%)
  • Internal medicine (27.44%)

What were the highlights of his more recent work (between 2014-2021)?

  • Nuclear receptor (46.98%)
  • Internal medicine (27.44%)
  • Endocrinology (26.05%)

In recent papers he was focusing on the following fields of study:

Thomas P. Burris mostly deals with Nuclear receptor, Internal medicine, Endocrinology, Cell biology and Agonist. His study in Nuclear receptor is interdisciplinary in nature, drawing from both Receptor, Inverse agonist and Cholesterol. His research in Internal medicine focuses on subjects like Cardiology, which are connected to Downregulation and upregulation.

His work deals with themes such as Heart disease and Knockout mouse, which intersect with Endocrinology. His research integrates issues of RAR-related orphan receptor gamma, Circadian clock, Gene expression and Endogeny in his study of Cell biology. His work carried out in the field of Agonist brings together such families of science as Retinoic acid, Neuroscience, Pharmacology and In vivo.

Between 2014 and 2021, his most popular works were:

  • Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis (94 citations)
  • Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis (94 citations)
  • Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice. (54 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Nuclear receptor, Internal medicine, Endocrinology, Circadian rhythm and Cell biology are his primary areas of study. His Nuclear receptor study combines topics from a wide range of disciplines, such as Agonist, Receptor, Regulation of gene expression and Inflammation. His Receptor research incorporates elements of Cell cycle, Triple Negative Breast Neoplasms, Triple-negative breast cancer and Estrogen receptor.

Thomas P. Burris regularly links together related areas like Type 1 diabetes in his Internal medicine studies. His work carried out in the field of Endocrinology brings together such families of science as Liver X receptor, Inverse agonist, Cell type and FOXP3. His Cell biology research is multidisciplinary, relying on both RAR-related orphan receptor gamma and Cytokine secretion.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

Vikas Chandra;Pengxiang Huang;Yoshitomo Hamuro;Srilatha Raghuram.
Nature (2008)

741 Citations

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Laura A. Solt;Yongjun Wang;Subhashis Banerjee;Travis G Hughes.
Nature (2012)

660 Citations

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ

Srilatha Raghuram;Keith R Stayrook;Pengxiang Huang;Pamela M Rogers.
Nature Structural & Molecular Biology (2007)

535 Citations

Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand

Laura A. Solt;P. Naresh Kumar;Philippe Nuhant;Yongjun Wang.
Nature (2011)

475 Citations

Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism.

K. Ganesh Kumar;James L. Trevaskis;Daniel D. Lam;Gregory M. Sutton.
Cell Metabolism (2008)

428 Citations

Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis

Guoqing Cao;Yu Liang;Carol L. Broderick;Brian A. Oldham.
Journal of Biological Chemistry (2003)

387 Citations

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.

Estelle Woldt;Yasmine Sebti;Laura A Solt;Christian Duhem.
Nature Medicine (2013)

367 Citations

A Dominant-negative Peroxisome Proliferator-activated Receptor γ (PPARγ) Mutant Is a Constitutive Repressor and Inhibits PPARγ-mediated Adipogenesis

Mark Gurnell;John M. Wentworth;Maura Agostini;Maria Adams.
Journal of Biological Chemistry (2000)

342 Citations

REV-ERB and ROR nuclear receptors as drug targets

Douglas J. Kojetin;Thomas P. Burris.
Nature Reviews Drug Discovery (2014)

334 Citations

The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor-α/γ Inverse Agonist

Naresh Kumar;Laura A. Solt;Juliana J. Conkright;Yongjun Wang.
Molecular Pharmacology (2010)

322 Citations

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