Thomas P. Burris focuses on Nuclear receptor, Receptor, Biochemistry, Cell biology and Endocrinology. His Nuclear receptor study combines topics in areas such as Oxysterol, Cellular differentiation and Cancer research. His Receptor research is multidisciplinary, incorporating elements of RAR-related orphan receptor alpha, Transcription factor, Estrogen receptor and Pharmacology.
Thomas P. Burris has researched Transcription factor in several fields, including Molecular biology, Psychological repression and ARNTL. The Cell biology study combines topics in areas such as Peroxisome proliferator-activated receptor and Autoimmune disease. The Endocrinology study which covers Internal medicine that intersects with Adrenal hypoplasia.
His scientific interests lie mostly in Nuclear receptor, Receptor, Internal medicine, Endocrinology and Cell biology. His Nuclear receptor research incorporates elements of Agonist and Retinoic acid. He focuses mostly in the field of Agonist, narrowing it down to matters related to Stereochemistry and, in some cases, Plasma protein binding.
The various areas that Thomas P. Burris examines in his Receptor study include RAR-related orphan receptor alpha, Immune system, Retinoic acid receptor, Farnesoid X receptor and Pharmacology. His study focuses on the intersection of Cell biology and fields such as RAR-related orphan receptor gamma with connections in the field of Interleukin 17. In his study, Warburg effect is inextricably linked to Inverse agonist, which falls within the broad field of Liver X receptor.
Thomas P. Burris mostly deals with Nuclear receptor, Internal medicine, Endocrinology, Cell biology and Agonist. His study in Nuclear receptor is interdisciplinary in nature, drawing from both Receptor, Inverse agonist and Cholesterol. His research in Internal medicine focuses on subjects like Cardiology, which are connected to Downregulation and upregulation.
His work deals with themes such as Heart disease and Knockout mouse, which intersect with Endocrinology. His research integrates issues of RAR-related orphan receptor gamma, Circadian clock, Gene expression and Endogeny in his study of Cell biology. His work carried out in the field of Agonist brings together such families of science as Retinoic acid, Neuroscience, Pharmacology and In vivo.
Nuclear receptor, Internal medicine, Endocrinology, Circadian rhythm and Cell biology are his primary areas of study. His Nuclear receptor study combines topics from a wide range of disciplines, such as Agonist, Receptor, Regulation of gene expression and Inflammation. His Receptor research incorporates elements of Cell cycle, Triple Negative Breast Neoplasms, Triple-negative breast cancer and Estrogen receptor.
Thomas P. Burris regularly links together related areas like Type 1 diabetes in his Internal medicine studies. His work carried out in the field of Endocrinology brings together such families of science as Liver X receptor, Inverse agonist, Cell type and FOXP3. His Cell biology research is multidisciplinary, relying on both RAR-related orphan receptor gamma and Cytokine secretion.
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Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA
Vikas Chandra;Pengxiang Huang;Yoshitomo Hamuro;Srilatha Raghuram.
Nature (2008)
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
Laura A. Solt;Yongjun Wang;Subhashis Banerjee;Travis G Hughes.
Nature (2012)
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ
Srilatha Raghuram;Keith R Stayrook;Pengxiang Huang;Pamela M Rogers.
Nature Structural & Molecular Biology (2007)
Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand
Laura A. Solt;P. Naresh Kumar;Philippe Nuhant;Yongjun Wang.
Nature (2011)
Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism.
K. Ganesh Kumar;James L. Trevaskis;Daniel D. Lam;Gregory M. Sutton.
Cell Metabolism (2008)
Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis
Guoqing Cao;Yu Liang;Carol L. Broderick;Brian A. Oldham.
Journal of Biological Chemistry (2003)
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.
Estelle Woldt;Yasmine Sebti;Laura A Solt;Christian Duhem.
Nature Medicine (2013)
A Dominant-negative Peroxisome Proliferator-activated Receptor γ (PPARγ) Mutant Is a Constitutive Repressor and Inhibits PPARγ-mediated Adipogenesis
Mark Gurnell;John M. Wentworth;Maura Agostini;Maria Adams.
Journal of Biological Chemistry (2000)
REV-ERB and ROR nuclear receptors as drug targets
Douglas J. Kojetin;Thomas P. Burris.
Nature Reviews Drug Discovery (2014)
The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor-α/γ Inverse Agonist
Naresh Kumar;Laura A. Solt;Juliana J. Conkright;Yongjun Wang.
Molecular Pharmacology (2010)
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