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Biology and Biochemistry

D-Index
81
Citations
21097
World Ranking
3942
National Ranking
1946

Overview

Thomas P. Burris is affiliated with Washington University in St. Louis in the United States. Their research spans several interconnected fields primarily within biochemistry, genetics, molecular biology, and medicine. The scientist's work addresses various subfields including molecular biology, physiology, genetics, endocrinology, diabetes, metabolism, and epidemiology.

The scientist's research topics include:

  • Receptor Mechanisms and Signaling
  • Estrogen and related hormone effects
  • Cholesterol and Lipid Metabolism
  • Diet, Metabolism, and Disease
  • Liver Disease Diagnosis and Treatment
  • Adipose Tissue and Metabolism
  • Retinoids in leukemia and cellular processes

Thomas P. Burris has contributed to multiple recent publications. Notable papers include:

  • "Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function," 2023, Circulation
  • "Restoration of the molecular clock is tumor suppressive in neuroblastoma," 2021, Nature Communications
  • "International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023," 2023, Pharmacological Reviews
  • "Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity," 2023, ACS Chemical Biology
  • "Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney," 2023, American Journal Of Pathology

Their frequent coauthors include:

  • Cyrielle Billon
  • Kristine Griffett
  • Bahaa Elgendy
  • John K. Walker
  • Lamees Hegazy

The scientist has published multiple papers in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation
  • ACS Chemical Biology
  • Journal of Pharmacology and Experimental Therapeutics
  • PLoS ONE

Best Publications

  • Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA.

    Vikas Chandra;Pengxiang Huang;Yoshitomo Hamuro;Srilatha Raghuram

  • Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

    Laura A. Solt;Yongjun Wang;Subhashis Banerjee;Travis G Hughes

  • Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ

    Srilatha Raghuram;Keith R Stayrook;Pengxiang Huang;Pamela M Rogers

  • Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism.

    K. Ganesh Kumar;James L. Trevaskis;Daniel D. Lam;Gregory M. Sutton

  • Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand

    Laura A. Solt;P. Naresh Kumar;Philippe Nuhant;Yongjun Wang

  • REV-ERB and ROR nuclear receptors as drug targets

    Douglas J. Kojetin;Thomas P. Burris

  • Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.

    Estelle Woldt;Yasmine Sebti;Laura A Solt;Christian Duhem

  • Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis

    Guoqing Cao;Yu Liang;Carol L. Broderick;Brian A. Oldham

  • The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor-α/γ Inverse Agonist

    Naresh Kumar;Laura A. Solt;Juliana J. Conkright;Yongjun Wang

  • A Dominant-negative Peroxisome Proliferator-activated Receptor γ (PPARγ) Mutant Is a Constitutive Repressor and Inhibits PPARγ-mediated Adipogenesis

    M Gurnell;J M Wentworth;M Agostini;M Adams

  • The coactivator LXXLL nuclear receptor recognition motif

    R.S. Savkur;T.P. Burris

  • The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing.

    Aria Baniahmad;Xiaohua Leng;T. P. Burris;S. Y. Tsai

  • Regulation of Carbohydrate Metabolism by the Farnesoid X Receptor

    Keith R. Stayrook;Kelli S. Bramlett;Rajesh S. Savkur;James Ficorilli

  • Nuclear Receptors and Their Selective Pharmacologic Modulators

    Thomas P. Burris;Laura A. Solt;Yongjun Wang;Christine Crumbley

  • Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor–coactivator interactions

    Anne-Marie Leduc;John O. Trent;James L. Wittliff;Kelli S. Bramlett

  • Action of RORs and their ligands in (patho)physiology

    Laura A. Solt;Thomas P. Burris

  • PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes.

    Patricia D. Pelton;Lubing Zhou;Keith T. Demarest;Thomas P. Burris

  • Expression of DAX-1, the Gene Responsible for X-Linked Adrenal Hypoplasia Congenita and Hypogonadotropic Hypogonadism, in the Hypothalamic-Pituitary-Adrenal/Gonadal Axis

    W.W. Guo;T.P. Burris;E.R.B. Mccabe

  • International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands

    Arthur Christopoulos;Jean Pierre Changeux;William A. Catterall;Doriano Fabbro

  • T0901317 is a dual LXR/FXR agonist.

    Keith A. Houck;Kristen M. Borchert;Christopher D. Hepler;Jeffrey S. Thomas

Frequent Co-Authors

Patrick R. Griffin
Patrick R. Griffin Scripps Research Institute
William R. Roush
William R. Roush Scripps Research Institute
Michael D. Cameron
Michael D. Cameron Scripps Research Institute
William W. Chin
William W. Chin Harvard Medical School
Jinsong Zhang
Jinsong Zhang Chinese Academy of Sciences
Michael J. Chalmers
Michael J. Chalmers Eli Lilly (United States)
Naresh Kumar
Naresh Kumar University of New South Wales
Kristopher W. Krausz
Kristopher W. Krausz National Institutes of Health
Hee-Jeong Im
Hee-Jeong Im University of Illinois at Chicago
Ali Keshavarzian
Ali Keshavarzian Rush University Medical Center

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