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Tze-chen Hsieh

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
8870
World Ranking
15247
National Ranking
6370

Tze-chen Hsieh publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Tze-chen Hsieh sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 157 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Tze-chen Hsieh D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Tze-chen Hsieh sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 55 D-Index — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Tze-chen Hsieh is affiliated with New York Medical College in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine with specific contributions to Molecular Biology, Geriatrics and Gerontology, Pulmonary and Respiratory Medicine, Surgery, and Oncology.

The scientist's work focuses on several main topics, including:

  • Sirtuins and Resveratrol in Medicine
  • Prostate Cancer Treatment and Research
  • Xenotransplantation and Immune Response
  • Cancer Cells and Metastasis
  • FOXO Transcription Factor Regulation
  • Cancer Genomics and Diagnostics
  • CRISPR and Genetic Engineering

Selected recent papers authored or coauthored by Tze-chen Hsieh include:

  • "Resveratrol Suppresses Prostate Cancer Epithelial Cell Scatter/Invasion by Targeting Inhibition of Hepatocyte Growth Factor (HGF) Secretion by Prostate Stromal Cells and Upregulation of E-cadherin by Prostate Cancer Epithelial Cells," 2020, International Journal of Molecular Sciences
  • "Trailblazing Perspectives on Targeting Breast Cancer Stem Cells," 2021, Pharmacology & Therapeutics
  • "Elucidating the Inhibitory Effect of Resveratrol and Its Structural Analogs on Selected Nucleotide-Related Enzymes," 2020, Biomolecules

Their published work is frequently found in venues such as:

  • International Journal of Molecular Sciences
  • Pharmacology & Therapeutics
  • Biomolecules

Collaboration plays a role in their research, with frequent coauthors including:

  • Joseph Wu
  • Juntao Li
  • Dan Qi
  • Jason H. Huang
  • Erxi Wu

Tze-chen Hsieh's interdisciplinary approach involves combining molecular biology techniques with clinical insights to address complex biological mechanisms underlying cancer, immune response, and aging-related processes. Their research on resveratrol, a compound with potential therapeutic roles, ties together biochemical pathways and translational medicine.

Best Publications

  • DIFFERENTIAL EFFECTS ON GROWTH, CELL CYCLE ARREST, AND INDUCTION OF APOPTOSIS BY RESVERATROL IN HUMAN PROSTATE CANCER CELL LINES

    Tze-chen Hsieh;Joseph M. Wu

  • Mechanism of cardioprotection by resveratrol, a phenolic antioxidant present in red wine (Review)

    Joseph M. Wu;Zhi-Rong Wang;Tze-Chen Hsieh;Jed L. Bruder

  • Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2.

    Tze-chen Hsieh;Gloria Juan;Zbigniew Darzynkiewicz;Joseph M. Wu

  • Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells.

    Yue Fu;Tze-chen Hsieh;Junqiao Guo;Jan Kunicki

  • Crystal Structure of Quinone Reductase 2 in Complex with Resveratrol

    Leonid Buryanovskyy;Yue Fu;Molly Boyd;Yuliang Ma

  • Simultaneous Human Granulocytic Ehrlichiosis and Lyme Borreliosis

    Robert B. Nadelman;Harold W. Horowitz;Tze-chen Hsieh;Joseph M. Wu

  • Differential control of growth, cell cycle progression, and expression of NF-κB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens

    Tze Chen Hsieh;E. Kithsiri Wijeratne;Jing Yu Liang;A. Leslie Gunatilaka

  • Dealcoholized red wine containing known amounts of resveratrol suppresses atherosclerosis in hypercholesterolemic rabbits without affecting plasma lipid levels

    Zhirong Wang;Jiangang Zou;Kejiang Cao;Tze-Chen Hsieh

  • Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials.

    T C Hsieh;P Burfeind;K Laud;J M Backer

  • Resveratrol: a cardioprotective substance.

    Joseph M. Wu;Tze-chen Hsieh

  • Anti-cancer activities of tea epigallocatechin-3-gallate in breast cancer patients under radiotherapy.

    G. Zhang;Y. Wang;Y. Zhang;X. Wan

  • Mechanism of fenretinide (4-HPR)-induced cell death.

    J. M. Wu;A. M. DiPietrantonio;T.-C. Hsieh

  • Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry.

    Piotr Smolewski;Elzbieta Bedner;Litong Du;Tze-Chen Hsieh

  • Effects of the flavonoid baicalin and its metabolite baicalein on androgen receptor expression, cell cycle progression and apoptosis of prostate cancer cell lines.

    S. Chen;Q. Ruan;E. Bedner;A. Deptala

  • Salinomycin: A Novel Anti-Cancer Agent with Known Anti-Coccidial Activities

    Shuang Zhou;Fengfei Wang;Eric T. Wong;Ekokobe Fonkem

  • Activation of Caspase 3 in HL-60 Cells Exposed to Hydrogen Peroxide

    Anna M. DiPietrantonio;Tze-chen Hsieh;Joseph M. Wu

  • Induction of quinone reductase NQO1 by resveratrol in human K562 cells involves the antioxidant response element ARE and is accompanied by nuclear translocation of transcription factor Nrf2.

    Tze-chen Hsieh;Xiaohua Lu;Zhirong Wang;Joseph M Wu

  • Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and γ-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells

    Tze-Chen Hsieh;Joseph M Wu

  • Inhibition of melanoma cell proliferation by resveratrol is correlated with upregulation of quinone reductase 2 and p53.

    Tze-chen Hsieh;Zhirong Wang;Carl V. Hamby;Joseph M. Wu

  • Grape-derived chemopreventive agent resveratrol decreases prostate-specific antigen (PSA) expression in LNCaP cells by an androgen receptor (AR)-independent mechanism.

    Hsieh Tc;Wu Jm

Frequent Co-Authors

Joseph M. Wu
Joseph M. Wu New York Medical College
Zbigniew Darzynkiewicz
Zbigniew Darzynkiewicz New York Medical College
Erxi Wu
Erxi Wu Scott & White Memorial Hospital
Gary P. Wormser
Gary P. Wormser New York Medical College
Frank Traganos
Frank Traganos New York Medical College
Min Wu
Min Wu University of North Dakota
Ira Schwartz
Ira Schwartz New York Medical College
J. Stephen Dumler
J. Stephen Dumler Uniformed Services University of the Health Sciences
Leroy F. Liu
Leroy F. Liu Taipei Medical University
Robert B. Nadelman
Robert B. Nadelman New York Medical College

External Links

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Best Scientists Citing Tze-chen Hsieh

Zbigniew Darzynkiewicz

Zbigniew Darzynkiewicz

New York Medical College

Publications: 43

J. Stephen Dumler

J. Stephen Dumler

Uniformed Services University of the Health Sciences

Publications: 31

John M. Pezzuto

John M. Pezzuto

Western New England University

Publications: 23

Jean A. Boutin

Jean A. Boutin

Institut de Recherches Internationales Servier

Publications: 22

Gary P. Wormser

Gary P. Wormser

New York Medical College

Publications: 17

Yasuko Rikihisa

Yasuko Rikihisa

The Ohio State University

Publications: 16

Paul J. Davis

Paul J. Davis

Albany Medical Center Hospital

Publications: 16

Mikhail V. Blagosklonny

Mikhail V. Blagosklonny

Roswell Park Cancer Institute

Publications: 15

Erol Fikrig

Erol Fikrig

Yale University

Publications: 14

Zoltan Ungvari

Zoltan Ungvari

University of Oklahoma Health Sciences Center

Publications: 14

Anna Csiszar

Anna Csiszar

University of Oklahoma Health Sciences Center

Publications: 14

Erxi Wu

Erxi Wu

Scott & White Memorial Hospital

Publications: 13

Philippe Delagrange

Philippe Delagrange

Centre national de la recherche scientifique, CNRS

Publications: 13

David H. Walker

David H. Walker

The University of Texas Medical Branch at Galveston

Publications: 12

Andrew D. Mesecar

Andrew D. Mesecar

Purdue University West Lafayette

Publications: 12

Anupam Bishayee

Anupam Bishayee

Lake Erie College of Osteopathic Medicine

Publications: 12

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