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Brigitte Bressac-de Paillerets

Brigitte Bressac-de Paillerets

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Genetics
France
2024

D-Index & Metrics

Genetics

D-Index
73
Citations
22266
World Ranking
2032
National Ranking
90

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award

Overview

Brigitte Bressac-de Paillerets is affiliated with the Institut Gustave Roussy in France. Their research primarily spans the domains of biochemistry, genetics, and molecular biology, with significant contributions also in medicine. Their work encompasses various subfields including molecular biology, genetics, oncology, cancer research, and pulmonary and respiratory medicine.

The scientist's research focuses on several main topics, reflecting a broad interest in cancer biology and treatment. These topics include renal cell carcinoma treatment, renal and related cancers, BRCA gene mutations in cancer, cancer influenced by hypoxia and metabolism, cutaneous melanoma detection and management, CRISPR and genetic engineering, and advances in neuroendocrine tumor research.

Brigitte Bressac-de Paillerets has contributed to multiple recent publications, demonstrating a consistent engagement with cancer-related genetic research and treatments. Selected recent papers include:

  • "Melanoma Risk and Melanocyte Biology", 2020, Acta Dermato Venereologica
  • "Response to systemic therapy in fumarate hydratase-deficient renal cell carcinoma", 2021, European Journal of Cancer
  • "A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers", 2021, Nature Communications
  • "The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant", 2021, Genetics in Medicine
  • "FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells", 2021, Cell Death and Differentiation

Their frequent collaborators include Olivier Caron and Sophie Giraud, each with nine joint publications, followed by Richard J. Kahnoski with six, and Sandrine M. Caputo and Isabelle Coupier with five publications each.

Publication venues where Brigitte Bressac-de Paillerets has often contributed include Nature Communications and the Journal of Medical Genetics, with multiple papers also appearing in UNC Libraries, Annales de Dermatologie et de Vénéréologie - FMC, and Acta Dermato Venereologica.

Best Publications

  • p53 functions as a cell cycle control protein in osteosarcomas.

    L Diller;J Kassel;C E Nelson;M A Gryka

  • Genetic Testing in Pheochromocytoma or Functional Paraganglioma

    Laurence Amar;Jérôme Bertherat;Eric Baudin;Christiane Ajzenberg

  • Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers

    Gaëlle Bougeard;Mariette Renaux-Petel;Jean-Michel Flaman;Camille Charbonnier

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Geographical Variation in the Penetrance of CDKN2A Mutations for Melanoma

    D. Timothy Bishop;Florence Demenais;Alisa M. Goldstein;Wilma Bergman

  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

    Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub

  • Genome-wide association study identifies three loci associated with melanoma risk.

    D Timothy Bishop;Florence Demenais;Mark M Iles;Mark Harland

  • High-risk Melanoma Susceptibility Genes and Pancreatic Cancer, Neural System Tumors, and Uveal Melanoma across GenoMEL

    Alisa M. Goldstein;May Chan;Mark Harland;Elizabeth M. Gillanders

  • P53 germline mutations in childhood cancers and cancer risk for carrier individuals.

    A Chompret;L Brugières;M Ronsin;M Gardes

  • Prevalence of p16 and CDK4 Germline Mutations in 48 Melanoma-Prone Families in France

    Nadem Soufir;Marie-Françoise Avril;Agnès Chompret;Florence Demenais

  • 2009 version of the Chompret criteria for Li Fraumeni syndrome.

    Julie Tinat;Gaelle Bougeard;Stéphanie Baert-Desurmont;Stéphanie Vasseur

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

    Antonis C. Antoniou;Antonis C. Antoniou;Amanda B. Spurdle;Amanda B. Spurdle;Olga M. Sinilnikova;Olga M. Sinilnikova;Sue Healey;Sue Healey

  • Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma.

    Jianxin Shi;Xiaohong R. Yang;Bari Ballew;Melissa Rotunno

  • Germline BAP1 mutations predispose to renal cell carcinomas.

    Tatiana Popova;Lucie Hebert;Virginie Jacquemin;Sophie Gad

  • Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS)

    Mickaël Ohanna;Sandy Giuliano;Caroline Bonet;Véronique Imbert

  • PDGFRA germline mutation in a family with multiple cases of gastrointestinal stromal tumor

    Agnès Chompret;Caroline Kannengiesser;Michel Barrois;Philippe Terrier

  • Genome-wide association study identifies three new melanoma susceptibility loci

    Jennifer H. Barrett;Mark M. Iles;Mark Harland;John C. Taylor

  • Guidelines for splicing analysis in molecular diagnosis derived from a set of 327 combined in silico/in vitro studies on BRCA1 and BRCA2 variants.

    Claude Houdayer;Virginie Caux-Moncoutier;Sophie Krieger;Michel Barrois

  • Molecular basis of the Li–Fraumeni syndrome: an update from the French LFS families

    G Bougeard;R Sesboüé;S Baert-Desurmont;S Vasseur

Frequent Co-Authors

Florence Demenais
Florence Demenais Université Paris Cité
Marie-Françoise Avril
Marie-Françoise Avril Université Paris Cité
Alisa M. Goldstein
Alisa M. Goldstein National Institutes of Health
Susana Puig
Susana Puig University of Barcelona
Eitan Friedman
Eitan Friedman City University of New York
Graham J. Mann
Graham J. Mann Australian National University
Corine Bertolotto
Corine Bertolotto Université Côte d'Azur
Nicholas K. Hayward
Nicholas K. Hayward QIMR Berghofer Medical Research Institute

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