World's Best Scientists 2026 revealed!
Dennie T. Frederick

Dennie T. Frederick

Award Badge
Rising Stars
2025

D-Index & Metrics

Rising Stars

D-Index
63
Citations
30617
World Ranking
134
National Ranking
17

Biology and Biochemistry

D-Index
67
Citations
32194
World Ranking
8038
National Ranking
3645

Dennie T. Frederick publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Dennie T. Frederick sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 343 publications — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Dennie T. Frederick D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Dennie T. Frederick sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 67 D-Index — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Rising Stars Award

Overview

Dennie T. Frederick is affiliated with the Broad Institute in the United States. Their research spans several domains within the biological and medical sciences, with a focus on cancer and immunology. The primary fields of study in their work include Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broad areas, their subfields of study notably cover Oncology, Molecular Biology, Immunology, Cancer Research, and Radiology, Nuclear Medicine and Imaging.

Their scientific contributions concentrate on several main topics:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Cancer Genomics and Diagnostics
  • CAR-T cell therapy research
  • Melanoma and MAPK Pathways
  • Single-cell and spatial transcriptomics
  • Vaccines and immunoinformatics approaches

Dennie T. Frederick has published extensively, with notable papers including:

  • Spatially organized multicellular immune hubs in human colorectal cancer, 2021, Cell
  • Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma, 2021, Nature
  • Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring, 2020, Nature Medicine
  • In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer, 2022, Nature Immunology
  • Landscape of helper and regulatory antitumour CD4+ T cells in melanoma, 2022, Nature

The frequent co-authors collaborating with Dennie T. Frederick include:

  • Genevieve M. Boland
  • Keith T. Flaherty
  • Ryan J. Sullivan
  • Tatyana Sharova
  • Nir Hacohen

Typical publication venues for their research work are:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • Nature Communications
  • Nature

Best Publications

  • Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

    Itay Tirosh;Benjamin Izar;Benjamin Izar;Sanjay M. Prakadan;Marc H. Wadsworth

  • Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

    Ravid Straussman;Teppei Morikawa;Kevin Shee;Michal Barzily-Rokni

  • Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

    Leore T. Geller;Michal Barzily-Rokni;Tal Danino;Oliver H. Jonas;Oliver H. Jonas

  • Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.

    Moshe Sade-Feldman;Moshe Sade-Feldman;Keren Yizhak;Stacey L. Bjorgaard;Stacey L. Bjorgaard;John P. Ray

  • A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

    Livnat Jerby-Arnon;Parin Shah;Michael S. Cuoco;Christopher Rodman

  • BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma

    Dennie Tompers Frederick;Adriano Piris;Alexandria P. Cogdill;Zachary A. Cooper

  • Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF

    Rizwan Haq;Jonathan Shoag;Pedro Andreu-Perez;Satoru Yokoyama;Satoru Yokoyama

  • Resistance to checkpoint blockade therapy through inactivation of antigen presentation.

    Moshe Sade-Feldman;Moshe Sade-Feldman;Yunxin J. Jiao;Yunxin J. Jiao;Jonathan H. Chen;Jonathan H. Chen;Michael S. Rooney

  • Spatially organized multicellular immune hubs in human colorectal cancer

    Karin Pelka;Matan Hofree;Jonathan H. Chen;Siranush Sarkizova

  • Toward Minimal Residual Disease-Directed Therapy in Melanoma.

    Florian Rambow;Aljosja Rogiers;Oskar Marin-Bejar;Sara Aibar

  • Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

    Noam Auslander;Gao Zhang;Joo Sang Lee;Joo Sang Lee;Dennie T. Frederick

  • The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

    Luping Lin;Amit J Sabnis;Elton Chan;Victor Olivas

  • A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors

    David J. Konieczkowski;Cory M. Johannessen;Omar Abudayyeh;Jong Wook Kim

  • Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy.

    Melvyn T. Chow;Aleksandra J. Ozga;Rachel L. Servis;Dennie T. Frederick

  • MAP Kinase Pathway Alterations in BRAF-Mutant Melanoma Patients with Acquired Resistance to Combined RAF/MEK Inhibition

    Nikhil Wagle;Nikhil Wagle;Eliezer M. Van Allen;Eliezer M. Van Allen;Daniel J. Treacy;Dennie T. Frederick

  • Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

    Douglas B. Johnson;Monica V. Estrada;Roberto Salgado;Violeta Sanchez

  • A melanocyte lineage program confers resistance to MAP kinase pathway inhibition

    Cory M. Johannessen;Laura A. Johnson;Laura A. Johnson;Laura A. Johnson;Federica Piccioni;Aisha Townes

  • Targeted Next Generation Sequencing Identifies Markers of Response to PD-1 Blockade

    Douglas B. Johnson;Garrett M. Frampton;Matthew J. Rioth;Erik Yusko

  • BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice.

    Chengwen Liu;Weiyi Peng;Chunyu Xu;Yanyan Lou

  • Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

    I. Tirosh;B. Izar;D. Treacy;J. J. Trombetta

Frequent Co-Authors

Keith T. Flaherty
Keith T. Flaherty Harvard University
Ryan J. Sullivan
Ryan J. Sullivan Harvard University
Jennifer A. Wargo
Jennifer A. Wargo The University of Texas MD Anderson Cancer Center
Nir Hacohen
Nir Hacohen Harvard University
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Levi A. Garraway
Levi A. Garraway Roche (United States)
Xiaowei Xu
Xiaowei Xu University of Pennsylvania
Arlene H. Sharpe
Arlene H. Sharpe Harvard University
Lynn M. Schuchter
Lynn M. Schuchter University of Pennsylvania
David E. Fisher
David E. Fisher Harvard University

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