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Medicine

D-Index
81
Citations
22810
World Ranking
16709
National Ranking
551

Overview

Gilles Vassal is affiliated with the Institut Gustave Roussy in France, contributing extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research spans multiple subfields including pediatrics, perinatology and child health, oncology, molecular biology, pulmonary and respiratory medicine, and neurology.

The scientist's work frequently addresses key topics such as childhood cancer survivors' quality of life, neuroblastoma research and treatments, pharmaceutical studies and practices, lung cancer treatments and mutations, cancer genomics and diagnostics, CAR-T cell therapy research, and cancer therapeutics and mechanisms.

Vassal has published numerous papers in notable journals. Recent publications include:

  • "Rituximab for High-Risk, Mature B-Cell Non-Hodgkin's Lymphoma in Children," 2020, New England Journal of Medicine
  • "Molecular mechanisms of resistance to BRAF and MEK inhibitors in BRAFV600E non-small cell lung cancer," 2020, European Journal of Cancer
  • "Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma," 2020, European Journal of Cancer
  • "Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients," 2021, Neuro-Oncology Advances
  • "ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients," 2020, European Journal of Cancer

Frequent publication venues where Vassal's work appears include:

  • European Journal of Cancer
  • Journal of Clinical Oncology
  • Cancer Research
  • The Lancet Oncology
  • Neuro-Oncology

Scientific collaboration is a significant aspect of Vassal's career. Frequent co-authors include Birgit Geoerger, Andrew D.J. Pearson, Lynley V. Marshall, Karsten Nysom, and Teresa de Rojas, with whom they have worked on numerous projects.

Vassal's research contributes to understanding and developing treatments for pediatric cancers, as well as exploring resistance mechanisms in lung cancer and innovative diagnostic techniques. Their body of work also covers advancing checkpoint inhibitor therapies for pediatric patients and highlights multiple clinical and translational research efforts focused on improving therapeutic strategies and outcomes in oncology and related medical fields.

Best Publications

  • The landscape of genomic alterations across childhood cancers

    Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  • High-throughput genomics and clinical outcome in hard-to-treat advanced cancers: Results of the MOSCATO 01 trial

    Christophe Massard;Stefan Michiels;Charles Ferté;Marie-Cécile Le Deley

  • Risk stratification of childhood medulloblastoma in the molecular era: the current consensus

    Vijay Ramaswamy;Marc Remke;Eric Bouffet;Simon Bailey

  • Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array

    Fabrice Andre;Bastien Job;Philippe Dessen;Philippe Dessen;Attila Tordai

  • Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial

    Ruth Ladenstein;Ruth Ladenstein;Ulrike Pötschger;Andrew D J Pearson;Penelope Brock

  • Differentiated thyroid carcinoma in childhood: long term follow-up of 72 patients.

    M. Schlumberger;F. De Vathaire;J. P. Travagli;G. Vassal

  • Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting.

    Irène Brigger;Jackie Morizet;Geneviève Aubert;Hélène Chacun

  • Metabolism of Irinotecan (CPT-11) by CYP3A4 and CYP3A5 in Humans

    Alexandre Santos;Sylvie Zanetta;Thierry Cresteil;Alain Deroussent

  • Impact of monitoring plasma 1,1-dichlorodiphenildichloroethane (o,p'DDD) levels on the treatment of patients with adrenocortical carcinoma

    E. Baudin;G. Pellegriti;M. Bonnay;A. Penfornis

  • Rituximab for High-Risk, Mature B-Cell Non-Hodgkin’s Lymphoma in Children

    Véronique Minard-Colin;Anne Aupérin;Marta Pillon;G.A. Amos Burke

  • Risk of Secondary Leukemia After a Solid Tumor in Childhood According to the Dose of Epipodophyllotoxins and Anthracyclines: A Case-Control Study by the Société Française d’Oncologie Pédiatrique

    Marie-Cécile Le Deley;Thierry Leblanc;Akthar Shamsaldin;Marie-Anne Raquin

  • Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.

    Stephanie Puget;Cathy Philippe;Dorine A. Bax;Bastien Job

  • Potential of the Conditionally Replicative Adenovirus Ad5-Δ24RGD in the Treatment of Malignant Gliomas and Its Enhanced Effect with Radiotherapy

    Martine L.M. Lamfers;Jacques Grill;Clemens M.F. Dirven;Victor W. Van Beusechem

  • Dose-dependent Neurotoxicity of High-Dose Busulfan in Children: A Clinical and Pharmacological Study

    Gilles Vassal;Alain Deroussent;Olivier Hartmann;Dominique Challine

  • A phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: Results of a Sarcoma Alliance for Research Through Collaboration study

    Alberto S. Pappo;Gilles Vassal;John J. Crowley;Vanessa Bolejack

  • Radiation dose, chemotherapy and risk of soft tissue sarcoma after solid tumours during childhood.

    Axelle Menu-Branthomme;Carole Rubino;Akhtar Shamsaldin;Michael M. Hawkins

  • Population Pharmacokinetics and Pharmacogenetics of Imatinib in Children and Adults

    Aurélie Petain;Darouna Kattygnarath;Julie Azard;Etienne Chatelut

  • Pharmacokinetic-pharmacodynamic relationships of imatinib and its main metabolite in patients with advanced gastrointestinal stromal tumors.

    Catherine Delbaldo;Etienne Chatelut;Micheline Ré;Alain Deroussent

  • MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated HOX/Stem Cell Gene Signature

    Nathalie Gaspar;Lynley Marshall;Lara Perryman;Dorine A. Bax

  • Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: a study in 136 children.

    V Méresse;O Hartmann;G Vassal;E Benhamou

Frequent Co-Authors

Jacques Grill
Jacques Grill Institut Gustave Roussy
Andrew D.J. Pearson
Andrew D.J. Pearson Royal Marsden NHS Foundation Trust
François Doz
François Doz Université Paris Cité
Fabrice Andre
Fabrice Andre Institut Gustave Roussy
Jean-Charles Soria
Jean-Charles Soria Amgen (United States)
Chris Jones
Chris Jones Institute of Cancer Research
Stefan Michiels
Stefan Michiels University of Paris-Saclay
Laurence Brugières
Laurence Brugières Institut Gustave Roussy
Thierry de Baere
Thierry de Baere Institut Gustave Roussy
Kathy Pritchard-Jones
Kathy Pritchard-Jones University College London

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