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Microbiology

D-Index
61
Citations
10959
World Ranking
3043
National Ranking
1203

Overview

Ryan K. Shields is affiliated with the University of Pittsburgh in the United States. Their research primarily centers on infectious diseases and antimicrobial resistance, with a significant focus on the challenges related to antibiotic-resistant bacteria.

Their recent publications reflect an engagement with critical issues in clinical microbiology and infectious diseases. Selected papers include:

  • Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections, 2023, Clinical Infectious Diseases
  • Clinical Evolution of AmpC-Mediated Ceftazidime-Avibactam and Cefiderocol Resistance in Enterobacter cloacae Complex Following Exposure to Cefepime, 2020, Clinical Infectious Diseases

Frequent co-authors collaborate with Shields on various research projects. Notable collaborators include:

  • Ellen G Kline
  • Daria Van Tyne
  • Yohei Doi
  • Lloyd Clarke
  • Kevin M Squires

Shields publishes frequently in several peer-reviewed journals, contributing to the following venues extensively:

  • Open Forum Infectious Diseases
  • Clinical Infectious Diseases
  • Antimicrobial Agents and Chemotherapy
  • Journal of Antimicrobial Chemotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)

Their research falls within the broader fields of Medicine and Biochemistry, Genetics and Molecular Biology. More specifically, their subfields of focus include:

  • Molecular Medicine
  • Pharmacology
  • Epidemiology
  • Applied Microbiology and Biotechnology
  • Infectious Diseases

Within these domains, several key topics characterize Shields' work, including:

  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Antibiotic Use and Resistance
  • Bacterial Identification and Susceptibility Testing
  • Antimicrobial Resistance in Staphylococcus
  • Pneumonia and Respiratory Infections
  • Infective Endocarditis Diagnosis and Management

Best Publications

  • Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.

    Raul G. Nogueira;Ashutosh P. Jadhav;Diogo C. Haussen;Alain Bonafe

  • Ceftazidime-Avibactam Is Superior to Other Treatment Regimens against Carbapenem-Resistant Klebsiella pneumoniae Bacteremia.

    Ryan K. Shields;M. Hong Nguyen;Liang Chen;Ellen G. Press

  • Emergence of Ceftazidime-Avibactam Resistance Due to Plasmid-Borne blaKPC-3 Mutations during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections.

    Ryan K. Shields;Liang Chen;Shaoji Cheng;Kalyan D. Chavda

  • Colistin-Resistant Acinetobacter baumannii: Beyond Carbapenem Resistance

    Zubair A. Qureshi;Lauren E. Hittle;Jessica A. O'Hara;Jesabel I. Rivera

  • Clinical Outcomes, Drug Toxicity, and Emergence of Ceftazidime-Avibactam Resistance Among Patients Treated for Carbapenem-Resistant Enterobacteriaceae Infections.

    Ryan K. Shields;Brian A. Potoski;Ghady Haidar;Binghua Hao

  • Performance of Candida Real-time Polymerase Chain Reaction, β-D-Glucan Assay, and Blood Cultures in the Diagnosis of Invasive Candidiasis

    M. Hong Nguyen;Mark C. Wissel;Ryan K. Shields;Martin A. Salomoni

  • Pneumonia and Renal Replacement Therapy Are Risk Factors for Ceftazidime-Avibactam Treatment Failures and Resistance among Patients with Carbapenem-Resistant Enterobacteriaceae Infections.

    Ryan K. Shields;M. Hong Nguyen;Liang Chen;Ellen G. Press

  • Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance.

    Ghady Haidar;Nathan J Philips;Ryan K Shields;Daniel Snyder

  • Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods:

    Tudor G Jovin;Jeffrey L Saver;Marc Ribo;Vitor Pereira

  • Mutations in blaKPC-3 That Confer Ceftazidime-Avibactam Resistance Encode Novel KPC-3 Variants That Function as Extended-Spectrum β-Lactamases

    Ghady Haidar;Cornelius J. Clancy;Ryan K. Shields;Binghua Hao

  • Comparison of an Aspergillus Real-time Polymerase Chain Reaction Assay With Galactomannan Testing of Bronchoalvelolar Lavage Fluid for the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplant Recipients

    Me Linh Luong;Cornelius J. Clancy;Aniket Vadnerkar;Eun Jeong Kwak

  • The presence of an FKS mutation rather than MIC is an independent risk factor for failure of echinocandin therapy among patients with invasive candidiasis due to Candida glabrata

    Ryan K. Shields;M. Hong Nguyen;Ellen G. Press;Andrea L. Kwa

  • Prospective, observational study of voriconazole therapeutic drug monitoring among lung transplant recipients receiving prophylaxis: factors impacting levels of and associations between serum troughs, efficacy, and toxicity.

    Dimitra Mitsani;M. Hong Nguyen;Ryan K. Shields;Yoshiya Toyoda

  • Effects of Klebsiella pneumoniae Carbapenemase Subtypes, Extended-Spectrum β-Lactamases, and Porin Mutations on the In Vitro Activity of Ceftazidime-Avibactam against Carbapenem-Resistant K. pneumoniae

    Ryan K. Shields;Cornelius J. Clancy;Binghua Hao;Liang Chen

  • Epidemiology, Clinical Characteristics and Outcomes of Extensively Drug-Resistant Acinetobacter baumannii Infections among Solid Organ Transplant Recipients

    Ryan K. Shields;Cornelius J. Clancy;Louise M. Gillis;Eun J. Kwak

  • Intra-Abdominal Candidiasis: The Importance of Early Source Control and Antifungal Treatment.

    Pascalis Vergidis;Cornelius J. Clancy;Ryan K. Shields;Seo Young Park

  • Emergence of Ceftazidime-Avibactam Resistance and Restoration of Carbapenem Susceptibility in Klebsiella pneumoniae Carbapenemase-Producing K pneumoniae: A Case Report and Review of Literature

    Ryan K. Shields;M. Hong Nguyen;Ellen G. Press;Liang Chen

  • Carbapenem-Resistant Klebsiella pneumoniae Strains Exhibit Diversity in Aminoglycoside-Modifying Enzymes, Which Exert Differing Effects on Plazomicin and Other Agents

    Reem Almaghrabi;Cornelius J. Clancy;Cornelius J. Clancy;Yohei Doi;Binghua Hao

  • Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.

    Melissa D. Barnes;Melissa D. Barnes;Marisa L. Winkler;Marisa L. Winkler;Magdalena A. Taracila;Magdalena A. Taracila;Malcolm G. Page

  • Identifying Spectra of Activity and Therapeutic Niches for Ceftazidime-Avibactam and Imipenem-Relebactam against Carbapenem-Resistant Enterobacteriaceae.

    Ghady Haidar;Cornelius J. Clancy;Liang Chen;Palash Samanta

  • Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections

    Unknown

  • Abdominal Candidiasis Is a Hidden Reservoir of Echinocandin Resistance

    Ryan K. Shields;M. Hong Nguyen;Ellen G. Press;Cornelius J. Clancy

Frequent Co-Authors

Cornelius J. Clancy
Cornelius J. Clancy University of Pittsburgh
M. Hong Nguyen
M. Hong Nguyen University of Pittsburgh
Yohei Doi
Yohei Doi University of Pittsburgh
Barry N. Kreiswirth
Barry N. Kreiswirth Center for Discovery and Innovation
Liang Chen
Liang Chen Hackensack Meridian Health Center for Discovery and Innovation
Joseph M. Pilewski
Joseph M. Pilewski University of Pittsburgh
David S. Liebeskind
David S. Liebeskind University of California, Los Angeles
A. William Pasculle
A. William Pasculle University of Pittsburgh
David S. Perlin
David S. Perlin Rutgers, The State University of New Jersey
Tudor G. Jovin
Tudor G. Jovin Cooper University Hospital

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