What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Genetics
Markus A. Rüegg focuses on Cell biology, Agrin, Neuromuscular junction, mTORC1 and mTORC2.
His biological study spans a wide range of topics, including Biochemistry, Immunology and Cytoskeleton, Utrophin.
His Agrin research includes elements of Dystroglycan and Alternative splicing, Gene isoform.
He has researched Neuromuscular junction in several fields, including Laminin, Extracellular matrix, Molecular biology and Postsynaptic potential.
His mTORC1 research integrates issues from Sirolimus, Endocrinology, Internal medicine, Skeletal muscle and Cell growth.
His studies in mTORC2 integrate themes in fields like Lipogenesis and Actin cytoskeleton.
His most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive (1676 citations)
- Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy (488 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Cell biology, Agrin, Neuromuscular junction, mTORC1 and Internal medicine.
Markus A. Rüegg interconnects Receptor and Cellular differentiation in the investigation of issues within Cell biology.
The study incorporates disciplines such as Laminin, Extracellular matrix and Gene isoform in addition to Agrin.
Within one scientific family, he focuses on topics pertaining to Postsynaptic potential under Neuromuscular junction, and may sometimes address concerns connected to Synapse.
His study focuses on the intersection of mTORC1 and fields such as Skeletal muscle with connections in the field of Autophagy.
Markus A. Rüegg works mostly in the field of Internal medicine, limiting it down to topics relating to Endocrinology and, in certain cases, Myasthenia gravis and Atrophy, as a part of the same area of interest.
He most often published in these fields:
- Cell biology (45.00%)
- Agrin (31.50%)
- Neuromuscular junction (27.50%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (45.00%)
- mTORC1 (22.50%)
- mTORC2 (15.50%)
In recent papers he was focusing on the following fields of study:
Markus A. Rüegg mainly focuses on Cell biology, mTORC1, mTORC2, Skeletal muscle and Internal medicine.
His Cell biology study incorporates themes from Receptor, Neuromuscular junction, Cellular differentiation and Downregulation and upregulation.
He has included themes like Motor neuron, Gene expression, Anatomy and Agrin in his Neuromuscular junction study.
His mTORC1 research is multidisciplinary, relying on both Autophagy, Homeostasis, Cell growth, RPTOR and Neuroscience.
His study in mTORC2 is interdisciplinary in nature, drawing from both Regulator, Embryonic stem cell and Stem cell.
His Internal medicine research is multidisciplinary, incorporating elements of Endocrinology and Kinase activity.
Between 2013 and 2021, his most popular works were:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Mechanisms Regulating Neuromuscular Junction Development and Function and Causes of Muscle Wasting (155 citations)
- Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination (89 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Genetics
Markus A. Rüegg mainly investigates mTORC1, Cell biology, mTORC2, PI3K/AKT/mTOR pathway and Internal medicine.
His mTORC1 study combines topics in areas such as Acute kidney injury and RPTOR.
His Cell biology research incorporates elements of Biochemistry, Cell growth and Cellular differentiation.
His PI3K/AKT/mTOR pathway research is multidisciplinary, incorporating perspectives in Translation, Eukaryotic initiation factor, Molecular biology and Protein kinase B.
His studies examine the connections between Protein kinase B and genetics, as well as such issues in TSC2, with regards to Neuroscience.
His study looks at the intersection of Internal medicine and topics like Endocrinology with Protein kinase C, Heart failure and Reperfusion injury.
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