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Immunology

D-Index
68
Citations
27173
World Ranking
2543
National Ranking
1217

Overview

John Chan is affiliated with the Albert Einstein College of Medicine in the United States. The scientist's research spans multiple fields with a primary focus on Medicine and Immunology and Microbiology. Their work explores a range of subfields including Immunology, Infectious Diseases, Molecular Biology, Oncology, and Epidemiology.

Chan's research covers key topics such as:

  • Tuberculosis Research and Epidemiology
  • Immune responses and vaccinations
  • Mycobacterium research and diagnosis
  • Immune Response and Inflammation
  • Immunodeficiency and Autoimmune Disorders
  • Viral Infections and Outbreaks Research
  • Bacteriophages and microbial interactions

The scientist has contributed to a number of publications across notable venues. Frequent publication venues include:

  • The Journal of Immunology
  • International Journal of Molecular Sciences
  • Proceedings of the National Academy of Sciences
  • Frontiers in Oncology
  • Vaccine

Among recent papers, John Chan is associated with works such as:

  • "Mycobacteriophages as Potential Therapeutic Agents against Drug-Resistant Tuberculosis" (2021), International Journal of Molecular Sciences
  • "Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates" (2022), Proceedings of the National Academy of Sciences
  • "Cell-free circulating tumor RNAs in plasma as the potential prognostic biomarkers in colorectal cancer" (2023), Frontiers in Oncology
  • "BCG-Prime and boost with Esx-5 secretion system deletion mutant leads to better protection against clinical strains of Mycobacterium tuberculosis" (2020), Vaccine
  • "Sinonasal cancer: an overview of the emerging subtypes" (2020), The Journal of Laryngology & Otology

Frequent collaborators in their scholarly work include:

  • William R. Jacobs
  • Steven A. Porcelli
  • Tony W. Ng
  • Rajagopalan Saranathan
  • Jiayong Xu

Best Publications

  • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

    Jo Anne L. Flynn;John Chan;Karla J. Triebold;Dyana K. Dalton

  • Immunology of tuberculosis.

    JoAnne L. Flynn;John Chan

  • Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice

    Jo Anne L. Flynn;Marsha M. Goldstein;John Chan;Karla J. Triebold

  • Tuberculosis: latency and reactivation.

    JoAnne L. Flynn;John Chan

  • Effects of Tumor Necrosis Factor Alpha on Host Immune Response in Chronic Persistent Tuberculosis: Possible Role for Limiting Pathology

    Vellore P. Mohan;Charles A. Scanga;Keming Yu;Holly M. Scott

  • Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection

    Jo Ann M. Tufariello;John Chan;Jo Anne L. Flynn

  • Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis.

    J Chan;K Tanaka;D Carroll;J Flynn

  • LIPOARABINOMANNAN, A POSSIBLE VIRULENCE FACTOR INVOLVED IN PERSISTENCE OF MYCOBACTERIUM TUBERCULOSIS WITHIN MACROPHAGES

    J. Chan;Xuedong Fan;S. W. Hunter;P. J. Brennan

  • Macrophages and control of granulomatous inflammation in tuberculosis

    J L Flynn;J Chan;P L Lin

  • Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension.

    Ming C. Tsai;Soumya Chakravarty;Guofeng Zhu;Jiayong Xu

  • Depletion of Cd4+ T Cells Causes Reactivation of Murine Persistent Tuberculosis despite Continued Expression of Interferon γ and Nitric Oxide Synthase 2

    Charles A. Scanga;V. P. Mohan;Keming Yu;Heather Joseph

  • Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis

    Mary K. Hondalus;Stoyan Bardarov;Robert Russell;John Chan

  • Immune evasion by Mycobacterium tuberculosis: living with the enemy

    Jo Anne L. Flynn;John Chan

  • B Cells Moderate Inflammatory Progression and Enhance Bacterial Containment upon Pulmonary Challenge with Mycobacterium tuberculosis

    Paul J. Maglione;Jiayong Xu;John Chan

  • Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis.

    Joseph Hinchey;Sunhee Lee;Bo Y. Jeon;Randall J. Basaraba

  • Reactivation of Latent Tuberculosis: Variations on the Cornell Murine Model

    Charles A. Scanga;V. P. Mohan;Heather Joseph;Keming Yu

  • Chemokines and tuberculosis

    Holly M.Scott Algood;John Chan;Jo Anne L. Flynn

  • Effects of aminoguanidine on latent murine tuberculosis

    JoAnne L. Flynn;Charles A. Scanga;Kathryn E. Tanaka;John Chan

  • Mycobacterium tuberculosis induces differential cytokine production from dendritic cells and macrophages with divergent effects on naive T cell polarization.

    Somia Perdow Hickman;John Chan;Padmini Salgame

  • How B cells shape the immune response against Mycobacterium tuberculosis

    Paul J. Maglione;John Chan

Frequent Co-Authors

William R. Jacobs
William R. Jacobs Albert Einstein College of Medicine
JoAnne L. Flynn
JoAnne L. Flynn University of Pittsburgh
Steven A. Porcelli
Steven A. Porcelli Albert Einstein College of Medicine
Barry R. Bloom
Barry R. Bloom Harvard University
Herbert B. Tanowitz
Herbert B. Tanowitz Albert Einstein College of Medicine
Louis M. Weiss
Louis M. Weiss Albert Einstein College of Medicine
Arturo Casadevall
Arturo Casadevall Johns Hopkins University
Murray Wittner
Murray Wittner Yeshiva University
Stephen M. Factor
Stephen M. Factor Albert Einstein College of Medicine
Denise E. Kirschner
Denise E. Kirschner University of Michigan–Ann Arbor

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