D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 10,162 131 World Ranking 2652 National Ranking 1258

Overview

What is she best known for?

The fields of study she is best known for:

  • Immune system
  • Internal medicine
  • Gene

Her primary areas of study are Immunology, Immune system, Mycobacterium tuberculosis, Tuberculosis and Cytokine. Her Immunology study frequently draws connections to adjacent fields such as Treatment strategy. The study incorporates disciplines such as Cancer research and Effector in addition to Immune system.

Her studies deal with areas such as Tumor necrosis factor alpha, Granuloma and Immunity as well as Mycobacterium tuberculosis. Her biological study spans a wide range of topics, including Inflammation and Chemokine. Her T cell research is multidisciplinary, relying on both Andrology and Virology.

Her most cited work include:

  • A methodology for performing global uncertainty and sensitivity analysis in systems biology (1313 citations)
  • Dynamics of HIV infection of CD4+ T cells (691 citations)
  • Modeling immunotherapy of the tumor-immune interaction. (571 citations)

What are the main themes of her work throughout her whole career to date?

Denise E. Kirschner focuses on Immunology, Immune system, Tuberculosis, Mycobacterium tuberculosis and Granuloma. Her Virology research extends to the thematically linked field of Immunology. Immune system is often connected to Effector in her work.

Her Tuberculosis research is multidisciplinary, incorporating elements of Antibiotics, Computational biology, Systems biology, Disease and In silico. She combines subjects such as Pathogen, Inflammation, Interferon gamma, Granuloma formation and Interleukin 10 with her study of Mycobacterium tuberculosis. The T cell study combines topics in areas such as Lymph node and Priming, Antigen.

She most often published in these fields:

  • Immunology (58.89%)
  • Immune system (40.00%)
  • Tuberculosis (37.22%)

What were the highlights of her more recent work (between 2017-2021)?

  • Tuberculosis (37.22%)
  • Granuloma (18.33%)
  • Mycobacterium tuberculosis (34.44%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Tuberculosis, Granuloma, Mycobacterium tuberculosis, Immunology and Immune system. The concepts of her Tuberculosis study are interwoven with issues in Pharmacokinetics, Clinical trial, Epidemiology and Computational biology, Systems biology. Her Immunology study combines topics in areas such as Antibiotics and Isoniazid.

Her research in Immune system intersects with topics in Myeloid, Myofibroblast, Lung and Cytokine. In her research, Bacterial cell structure is intimately related to T cell, which falls under the overarching field of Cytokine. Her Immunity research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine, Inflammation, Inflammatory response and Interleukin 10.

Between 2017 and 2021, her most popular works were:

  • Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology. (52 citations)
  • Low Levels of T Cell Exhaustion in Tuberculous Lung Granulomas. (19 citations)
  • Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations. (17 citations)

In her most recent research, the most cited papers focused on:

  • Immune system
  • Internal medicine
  • Gene

Tuberculosis, Immunology, Immune system, Vaccination and Immunity are her primary areas of study. Her work deals with themes such as Clinical trial, Epidemiology, Environmental health, Mortality rate and Cause of death, which intersect with Tuberculosis. Denise E. Kirschner is interested in Granuloma, which is a branch of Immunology.

Her Immune system study integrates concerns from other disciplines, such as Cytokine and Mycobacterium tuberculosis. Her Cytokine research includes elements of T cell, Lung and Bacterial cell structure. Her studies in Immunity integrate themes in fields like Inflammation, Proinflammatory cytokine, Neuroscience and Interleukin 10.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A methodology for performing global uncertainty and sensitivity analysis in systems biology

Simeone Marino;Ian B. Hogue;Christian J. Ray;Denise E. Kirschner.
Journal of Theoretical Biology (2008)

1667 Citations

Dynamics of HIV infection of CD4+ T cells

Alan S. Perelson;Denise E. Kirschner;Rob De Boer.
Bellman Prize in Mathematical Biosciences (1993)

1102 Citations

Modeling immunotherapy of the tumor-immune interaction.

Denise E. Kirschner;John Carl Panetta.
Journal of Mathematical Biology (1998)

907 Citations

Optimal control of the chemotherapy of HIV.

Denise Kirschner;Suzanne Lenhart;Steve Serbin.
Journal of Mathematical Biology (1997)

601 Citations

Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model.

Jose L. Segovia-Juarez;Suman Ganguli;Denise Kirschner.
Journal of Theoretical Biology (2004)

363 Citations

Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms

Joshua T. Mattila;Olabisi O. Ojo;Diane Kepka-Lenhart;Simeone Marino.
Journal of Immunology (2013)

292 Citations

Using Mathematics to Understand HIV Immune Dynamics

Denise Kirschner.
(1997)

288 Citations

A Model to Predict Cell-Mediated Immune Regulatory Mechanisms During Human Infection with Mycobacterium tuberculosis

Janis E. Wigginton;Denise Kirschner.
Journal of Immunology (2001)

284 Citations

The equilibria that allow bacterial persistence in human hosts

Martin J. Blaser;Denise E. Kirschner.
Nature (2007)

264 Citations

Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.

Hannah Priyadarshini Gideon;Jia Yao Phuah;Amy J. Myers;Bryan D. Bryson.
PLOS Pathogens (2015)

255 Citations

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