2026 Denise E. Kirschner: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	68	2574	2368	1229	1120	187	18235

Denise E. Kirschner publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Denise E. Kirschner sits on this spectrum.

62 publications 807+

This scientist: 187 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Denise E. Kirschner D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Denise E. Kirschner sits on this spectrum.

40 D-Index 157+

This scientist: 68 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Denise E. Kirschner is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on infectious diseases, especially tuberculosis, as well as related fields such as epidemiology and molecular biology. Their work spans various interdisciplinary areas including biomedical engineering and modeling and simulation.

Their recent publications reflect a strong emphasis on systems biology, disease modeling, and immunology. Among notable papers are:

To Sobol or not to Sobol? The effects of sampling schemes in systems biology applications, 2021, Mathematical Biosciences
Predicting the second wave of COVID-19 in Washtenaw County, MI, 2020, Journal of Theoretical Biology
Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation, 2020, PLoS Computational Biology
Neutrophil Dynamics Affect Mycobacterium tuberculosis Granuloma Outcomes and Dissemination, 2021, Frontiers in Immunology
Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas, 2020, Frontiers in Pharmacology

Denise E. Kirschner has collaborated frequently with several researchers, including:

Jennifer J. Linderman
JoAnne L. Flynn
Maral Budak
Joshua T. Mattila
Pauline Maiello

Their publications appear regularly in various scientific journals and preprint servers, notably:

bioRxiv (Cold Spring Harbor Laboratory)
Journal of Theoretical Biology
PLoS Computational Biology
Frontiers in Immunology
Frontiers in Pharmacology

Their main fields of study focus on medicine and biochemistry, genetics, and molecular biology. Subfields of their research include infectious diseases, epidemiology, molecular biology, modeling and simulation, and biomedical engineering.

The topics covered by their work include:

Tuberculosis Research and Epidemiology
Mycobacterium research and diagnosis
COVID-19 epidemiological studies
Innovative Microfluidic and Catalytic Techniques Innovation
Vaccines and immunoinformatics approaches
Infectious Diseases and Tuberculosis
Data-Driven Disease Surveillance

Best Publications

Dynamics of HIV infection of CD4+ T cells

Alan S. Perelson;Denise E. Kirschner;Rob De Boer

1262
Citations
Modeling immunotherapy of the tumor-immune interaction.

Denise E. Kirschner;John Carl Panetta

1101
Citations
Optimal control of the chemotherapy of HIV.

Denise Kirschner;Suzanne Lenhart;Steve Serbin

647
Citations
Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model.

Jose L. Segovia-Juarez;Suman Ganguli;Denise Kirschner

418
Citations
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms

Joshua T. Mattila;Olabisi O. Ojo;Diane Kepka-Lenhart;Simeone Marino

379
Citations
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.

Hannah Priyadarshini Gideon;Jia Yao Phuah;Amy J. Myers;Bryan D. Bryson

367
Citations
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology.

Joseph M. Cicchese;Stephanie Evans;Caitlin Hult;Louis R. Joslyn

330
Citations
A Model to Predict Cell-Mediated Immune Regulatory Mechanisms During Human Infection with Mycobacterium tuberculosis

Janis E. Wigginton;Denise Kirschner

308
Citations
Using Mathematics to Understand HIV Immune Dynamics

Denise Kirschner

298
Citations
A mathematical model of tumor-immune evasion and siRNA treatment

J.C. Arciero;T.L. Jackson;D.E. Kirschner

238
Citations
A model for treatment strategy in the chemotherapy of aids

Denise Kirschner;G. F. Webb

223
Citations
The human immune response to Mycobacterium tuberculosis in lung and lymph node.

Simeone Marino;Denise E. Kirschner

221
Citations
Macrophage Polarization Drives Granuloma Outcome during Mycobacterium tuberculosis Infection

Simeone Marino;Nicholas A. Cilfone;Joshua T. Mattila;Jennifer J. Linderman

210
Citations
Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation

Mohammad Fallahi-Sichani;Mohammed El-Kebir;Mohammed El-Kebir;Simeone Marino;Denise E. Kirschner

197
Citations
Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection.

Dhruv Sud;Carolyn Bigbee;JoAnne L. Flynn;Denise E. Kirschner

189
Citations
Synergy between Individual TNF-Dependent Functions Determines Granuloma Performance for Controlling Mycobacterium tuberculosis Infection

J. Christian J. Ray;JoAnne L. Flynn;Denise E. Kirschner

189
Citations
Systems biology of persistent infection: tuberculosis as a case study.

Douglas Young;Jaroslav Stark;Denise Kirschner

187
Citations
Dendritic cell trafficking and antigen presentation in the human immune response to Mycobacterium tuberculosis.

Simeone Marino;Santosh Pawar;Craig L. Fuller;Todd A. Reinhart

184
Citations
Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs.

Soumya D. Chakravarty;Guofeng Zhu;Ming C. Tsai;Vellore P. Mohan

184
Citations
Dynamics of Co-infection with M. tuberculosis and HIV-1

Denise E. Kirschner

171
Citations
Reevaluation of T Cell Receptor Excision Circles as a Measure of Human Recent Thymic Emigrants

Ping Ye;Denise E. Kirschner

168
Citations

Frequent Co-Authors

Jennifer J. Linderman University of Michigan–Ann Arbor

JoAnne L. Flynn University of Pittsburgh

Glenn F. Webb Vanderbilt University

Philana Ling Lin University of Pittsburgh

Todd A. Reinhart University of Pittsburgh

Mark J. Miller Washington University in St. Louis

Véronique Dartois Rutgers, The State University of New Jersey

Bethany B. Moore University of Michigan–Ann Arbor

John Chan Albert Einstein College of Medicine

Martin J. Blaser Rutgers, The State University of New Jersey

External Links

Personal website of Denise E. Kirschner

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