H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 117 Citations 66,750 394 World Ranking 136 National Ranking 92
Medicine D-index 124 Citations 70,753 470 World Ranking 1278 National Ranking 772

Research.com Recognitions

Awards & Achievements

2017 - Max Delbruck Prize, Division of Biological Physics of the American Physical Society For profound contributions to theoretical immunology, which bring insight and save lives.

2015 - Fellow of American Physical Society (APS) Citation For seminal contributions to the development of dynamical models of HIV infection, for elucidating therapeutic responses of HCV, and for helping found the fields of viral dynamics and theoretical immunology

2009 - SIAM Fellow For contributions to viral dynamics and other problems of mathematical biology.

2006 - Fellow of the American Association for the Advancement of Science (AAAS)

1999 - Fellow of the American Academy of Arts and Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Virus
  • Gene
  • Immune system

Alan S. Perelson mostly deals with Virology, Immunology, Virus, Viral load and Immune system. Within one scientific family, Alan S. Perelson focuses on topics pertaining to Antibody under Virology, and may sometimes address concerns connected to Immunity. His work in Immunology is not limited to one particular discipline; it also encompasses Pharmacotherapy.

His study in Virus is interdisciplinary in nature, drawing from both Viral evolution and In vivo. His Viral load study also includes fields such as

  • Virus latency and related Latency,
  • Hepatitis B virus which connect with Hepatitis B. He has researched Immune system in several fields, including Artificial immune system, Artificial intelligence and Viral dynamics.

His most cited work include:

  • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection (3861 citations)
  • HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time (3023 citations)
  • Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy (1910 citations)

What are the main themes of his work throughout his whole career to date?

Alan S. Perelson mainly focuses on Virology, Immunology, Virus, Viral load and Immune system. His work in Viral replication, Hepatitis C virus, Viremia, Viral disease and Interferon is related to Virology. His Hepatitis C virus study incorporates themes from Internal medicine and Hepatitis C.

His research combines Cytotoxic T cell and Immunology. His work deals with themes such as RNA, Acquired immunodeficiency syndrome and In vivo, which intersect with Virus. His work carried out in the field of Viral load brings together such families of science as Pharmacokinetics and Simian immunodeficiency virus.

He most often published in these fields:

  • Virology (49.60%)
  • Immunology (43.32%)
  • Virus (31.08%)

What were the highlights of his more recent work (between 2013-2021)?

  • Virology (49.60%)
  • Virus (31.08%)
  • Viral load (24.15%)

In recent papers he was focusing on the following fields of study:

Alan S. Perelson mainly investigates Virology, Virus, Viral load, Immunology and Viral replication. His research in Virology intersects with topics in RNA, Acquired immune system and Intracellular. He combines subjects such as In vitro and In vivo with his study of Virus.

The concepts of his Viral load study are interwoven with issues in Hepatitis C, Severe acute respiratory syndrome coronavirus 2, Sofosbuvir, Combination therapy and Simian immunodeficiency virus. His Immunology study integrates concerns from other disciplines, such as Transmission and Cytotoxic T cell. His Viral replication research incorporates elements of Genome, Alpha interferon, Outbreak and Basic reproduction number.

Between 2013 and 2021, his most popular works were:

  • Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues (438 citations)
  • Zika viral dynamics and shedding in rhesus and cynomolgus macaques. (210 citations)
  • Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys. (132 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Virus
  • Immune system

Alan S. Perelson mostly deals with Virology, Immunology, Virus, Viral load and Viral replication. His biological study spans a wide range of topics, including RNA and Genotype. His research is interdisciplinary, bridging the disciplines of Cytotoxic T cell and Immunology.

Alan S. Perelson works mostly in the field of Virus, limiting it down to topics relating to Epitope and, in certain cases, Vaccination, AIDS Vaccines, Mutation, Monoclonal antibody and Viral entry. The study incorporates disciplines such as Raltegravir Potassium, Viral evolution, Integrase inhibitor, Combination therapy and Raltegravir in addition to Viral load. In his work, Favipiravir is strongly intertwined with Basic reproduction number, which is a subfield of Viral replication.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

David D. Ho;Avidan U. Neumann;Alan S. Perelson;Wen Chen.
Nature (1995)

5796 Citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

Alan S. Perelson;Avidan U. Neumann;Martin Markowitz;John M. Leonard.
Science (1996)

4307 Citations

Self-nonself discrimination in a computer

Stephanie Forrest;Alan S. Perelson;Lawrence Allen;Rajesh Cherukuri.
ieee symposium on security and privacy (1994)

3022 Citations

Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy

Avidan U. Neumann;Nancy P. Lam;Harel Dahari;David R. Gretch.
Science (1998)

2640 Citations

Decay characteristics of HIV-1-infected compartments during combination therapy

Alan S. Perelson;Paulina Essunger;Yunzhen Cao;Mika Vesanen.
Nature (1997)

2163 Citations

The immune system, adaptation, and machine learning

J D Farmer;N H Packard;A S Perelson.
Physica D: Nonlinear Phenomena (1986)

2130 Citations

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

Brandon F. Keele;Elena E. Giorgi;Elena E. Giorgi;Jesus F. Salazar-Gonzalez;Julie M. Decker.
Proceedings of the National Academy of Sciences of the United States of America (2008)

1927 Citations

Mathematical Analysis of HIV-1 Dynamics in Vivo

Alan S. Perelson;Patrick W. Nelson.
Siam Review (1999)

1711 Citations

Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virus-infected macaques

Xia Jin;Daniel E. Bauer;Sarah E. Tuttleton;Sharon Lewin.
Journal of Experimental Medicine (1999)

1659 Citations

Modelling viral and immune system dynamics

Alan S. Perelson.
Nature Reviews Immunology (2002)

1047 Citations

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