World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
73
Citations
21429
World Ranking
1639
National Ranking
76

Medicine

D-Index
84
Citations
26356
World Ranking
15074
National Ranking
574

Overview

Rob J. de Boer is affiliated with Utrecht University in the Netherlands. Their research spans immunology, microbiology, and medicine, focusing on various subfields such as immunology, molecular biology, infectious diseases, virology, and oncology. The scientist's work concentrates primarily on T-cell and B-cell immunology, immune cell function and interaction, immunotherapy and immune responses, HIV research and treatment, CAR-T cell therapy research, HIV/AIDS research and interventions, and evolution and genetic dynamics.

Frequent publication venues for de Boer's research include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, eLife, PLoS Computational Biology, and SSRN Electronic Journal. Their frequent coauthors include José A. M. Borghans, Kiki Tesselaar, Julia Drylewicz, Peter C. de Greef, and Arpit Chandan Swain.

Recent papers authored or coauthored by Rob J. de Boer cover diverse themes within immunology and related biological sciences:

  • Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity (2021, Nature Communications)
  • The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes (2020, eLife)
  • Hematopoiesis in numbers (2021, Trends in Immunology)
  • CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cells in vitro (2020, Frontiers in Immunology)
  • Replicative history marks transcriptional and functional disparity in the CD8+ T cell memory pool (2022, Nature Immunology)

The research topics prominently addressed by de Boer highlight T-cell and B-cell immunology and the detailed mechanisms of immune cell function and interaction. Their work also engages with the development and understanding of immunotherapy approaches, especially CAR-T cell therapy, and the dynamics of immune responses related to HIV/AIDS.

Coauthors frequently collaborating with de Boer include:

  • José A. M. Borghans
  • Kiki Tesselaar
  • Julia Drylewicz
  • Peter C. de Greef
  • Arpit Chandan Swain

The scientist's contributions appear notably in journals dedicated to immunology and computational biology, reflecting an interdisciplinary approach that integrates molecular biology and clinical implications in immune-related diseases and therapies.

Best Publications

  • Lead times and overdetection due to prostate-specific antigen screening: estimates from the European Randomized Study of Screening for Prostate Cancer.

    Gerrit Draisma;Rob Boer;Suzie J. Otto;Ingrid W. van der Cruijsen

  • Overdiagnosis Due to Prostate-Specific Antigen Screening: Lessons From U.S. Prostate Cancer Incidence Trends

    Ruth Etzioni;David F. Penson;Julie M. Legler;Dante di Tommaso

  • Dynamics of HIV infection of CD4+ T cells

    Alan S. Perelson;Denise E. Kirschner;Rob De Boer

  • In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.

    Janesh Pillay;Ineke den Braber;Nienke Vrisekoop;Lydia M. Kwast

  • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation

    Nadine G. Pakker;Daan W. Notermans;Rob J. De Boer;Marijke T.L. Roos

  • Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

    Ineke den Braber;Tendai Mugwagwa;Nienke Vrisekoop;Liset Westera

  • Initiation of population-based mammography screening in Dutch municipalities and effect on breast-cancer mortality: a systematic review.

    Suzie J. Otto;Jacques Fracheboud;Caspar W. N. Looman;Mireille J. M. Broeders

  • Diverse and heritable lineage imprinting of early haematopoietic progenitors

    Shalin H Naik;Shalin H Naik;Leïla Perié;Leïla Perié;Erwin Swart;Carmen Gerlach

  • Heterogeneous differentiation patterns of individual CD8+ T cells.

    Carmen Gerlach;Jan C. Rohr;Jan C. Rohr;Leïla Perié;Leïla Perié;Nienke van Rooij

  • MHC polymorphism under host-pathogen coevolution.

    José A. M. Borghans;José A. M. Borghans;Joost B. Beltman;Rob J. De Boer

  • Different dynamics of CD4+ and CD8+ T cell responses during and after acute lymphocytic choriomeningitis virus infection

    Rob J. De Boer;Dirk Homann;Alan S. Perelson

  • Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen

    Silvia Ariotti;Joost B. Beltman;Grzegorz Chodaczek;Mirjam E. Hoekstra

  • Analysing immune cell migration

    Joost B. Beltman;Athanasius F. M. Marée;Rob J. de Boer

  • Quantifying T lymphocyte turnover.

    Rob J. De Boer;Rob J. De Boer;Alan S. Perelson;Alan S. Perelson

  • Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool.

    Nienke Vrisekoop;Ineke den Braber;Ineke den Braber;Anne Bregje de Boer;Anne Bregje de Boer;An F. C. Ruiter

  • Lymph node topology dictates T cell migration behavior

    Joost B. Beltman;Athanasius F.M. Marée;Jennifer N. Lynch;Mark J. Miller

  • How much can current interventions reduce colorectal cancer mortality in the U.S.? Mortality projections for scenarios of risk-factor modification, screening, and treatment.

    Iris Vogelaar;Marjolein van Ballegooijen;Deborah Schrag;Rob Boer

  • The effect of group size on time budgets and social behaviour in wild long-tailed macaques (macaca fascicularis)

    Carel P. van Schaik;Maria A. van Noordwijk;Rob J. de Boer;Isolde den Tonkelaar

  • Do most lymphocytes in humans really reside in the gut

    Vitaly V. Ganusov;Rob J. De Boer

  • A model for a smallpox-vaccination policy.

    Samuel A. Bozzette;Rob Boer;Vibha Bhatnagar;Jennifer L. Brower

  • Lead Times and Overdetection Due to Prostate-Specific Antigen Screening

    Gerrit Draisma;Rob Boer;Suzie J. Otto;Ingrid W van der Cruijsen

Frequent Co-Authors

Harry J. de Koning
Harry J. de Koning Erasmus University Rotterdam
Alan S. Perelson
Alan S. Perelson Los Alamos National Laboratory
J. Dik F. Habbema
J. Dik F. Habbema Erasmus University Rotterdam
Ann G. Zauber
Ann G. Zauber Memorial Sloan Kettering Cancer Center
Ton N. M. Schumacher
Ton N. M. Schumacher Antoni van Leeuwenhoek Hospital
Frank Miedema
Frank Miedema Utrecht University
Sidney J. Winawer
Sidney J. Winawer Memorial Sloan Kettering Cancer Center
Dörte Hamann
Dörte Hamann University Medical Center Utrecht
Eric J. Feuer
Eric J. Feuer National Institutes of Health
Becca Asquith
Becca Asquith Imperial College London

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