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Overview

Brian Meehan is affiliated with the Commonwealth Scientific and Industrial Research Organisation in Australia. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, as well as medicine.

Their work spans several subfields including molecular biology, cancer research, immunology, genetics, and oncology. The main topics of their research include extracellular vesicles in disease, glioma diagnosis and treatment, microRNA in disease regulation, chromatin remodeling and cancer, cancer mechanisms and therapy, gut microbiota and health, and immune cells in cancer.

Brian Meehan has contributed extensively to peer-reviewed journals, with frequent publications in the following venues:

  • Neuro-Oncology
  • Nature Communications
  • Neuro-Oncology Advances
  • Cancer Research
  • Blood Advances

Their recent scientific papers include:

  • Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles, 2021, Blood Advances
  • SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria, 2021, Nature Communications
  • Synthetic glycans control gut microbiome structure and mitigate colitis in mice, 2022, Nature Communications
  • Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells, 2022, Nature Communications
  • Oncogenic RAS drives the CRAF-dependent extracellular vesicle uptake mechanism coupled with metastasis, 2021, Journal of Extracellular Vesicles

Their frequent collaborators include Janusz Rak, Lata Adnani, Nadim Tawil, Laura Montermini, and Sidong Huang, indicating a network of joint research efforts.

Best Publications

  • Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

    Khalid Al-Nedawi;Brian Meehan;Johann Micallef;Vladimir Lhotak

  • Isolation of Porcine Circovirus-like Viruses from Pigs with a Wasting Disease in the USA and Europe:

    G. M. Allan;F. McNeilly;S. Kennedy;B. Daft

  • Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome.

    J Ellis;L Hassard;E Clark;J Harding

  • Characterization of novel circovirus DNAs associated with wasting syndromes in pigs.

    Brian M. Meehan;Francis McNeilly;Daniel Todd;Seamus Kennedy

  • Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus.

    G.M. Allan;S. Kennedy;F. McNeilly;J.C. Foster

  • Microvesicles as mediators of intercellular communication in cancer—the emerging science of cellular ‘debris’

    Unknown

  • Viral wasting syndrome of swine: experimental reproduction of postweaning multisystemic wasting syndrome in gnotobiotic swine by coinfection with porcine circovirus 2 and porcine parvovirus.

    S. Krakowka;J. A. Ellis;B. Meehan;S. Kennedy

  • Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication.

    G. M. Allan;F. McNeilly;J. Ellis;S. Krakowka

  • Reproduction of Lesions of Postweaning Multisystemic Wasting Syndrome in Gnotobiotic Piglets

    John Ellis;Steven Krakowka;Michael Dale Lairmore;Deborah Haines

  • Reproduction of lesions of postweaning multisystemic wasting syndrome by infection of conventional pigs with porcine circovirus type 2 alone or in combination with porcine parvovirus.

    S Kennedy;D Moffett;F McNeilly;B Meehan

  • Isolation and characterisation of circoviruses from pigs with wasting syndromes in Spain, Denmark and Northern Ireland.

    G.M Allan;F Mc Neilly;B.M Meehan;S Kennedy

  • Sequence of porcine circovirus DNA: affinities with plant circoviruses

    Brian Meehan;J L Creelan;M S McNulty;D Todd

  • Coinfection by porcine circoviruses and porcine parvovirus in pigs with naturally acquired postweaning multisystemic wasting syndrome.

    J. A. Ellis;A. Bratanich;E. G. Clark;G. Allan

  • Development and application of a competitive enzyme-linked immunosorbent assay for the detection of serum antibodies to porcine circovirus type 2.

    Ian W. Walker;Carrie A. Konoby;Victoria A. Jewhurst;Irene McNair

  • Phylogeny and systematics of 18 Colletotrichum species based on ribosomal DNA spacer sequences.

    S Sreenivasaprasad;P R Mills;B M Meehan;A E Brown

  • Novel porcine circoviruses from pigs with wasting disease syndromes.

    G. Allan;B. Meehan;D. Todd;S. Kennedy

  • Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells.

    Unknown

  • In vitro studies on the infection and replication of porcine circovirus type 2 in cells of the porcine immune system.

    D.F. Gilpin;K. McCullough;B.M. Meehan;F. McNeilly

  • Isolation and characterization of porcine circovirus 2 from cases of sow abortion and porcine dermatitis and nephropathy syndrome.

    B. M. Meehan;F. McNeilly;I. McNair;I. Walker

  • Dendritic Cells Harbor Infectious Porcine Circovirus Type 2 in the Absence of Apparent Cell Modulation or Replication of the Virus

    I. E. Vincent;C. P. Carrasco;B. Herrmann;B. M. Meehan

  • Production, characterisation and applications of monoclonal antibodies to porcine circovirus 2.

    F. McNeilly;I. McNair;D. P. Mackie;B. M. Meehan

  • Characterization of viral DNAs from cells infected with chicken anaemia agent: sequence analysis of the cloned replicative form and transfection capabilities of cloned genome fragments.

    B. M. Meehan;D. Todd;J. L. Creelan;J. A. P. Earle

  • The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model.

    Karla Jean Fullner;John C. Boucher;Martha A. Hanes;G. Kenneth Haines

Frequent Co-Authors

Gordon Allan
Gordon Allan Queen's University Belfast
John A. Ellis
John A. Ellis Western University of Health Sciences
Deborah M. Haines
Deborah M. Haines Western University of Health Sciences
Steven Krakowka
Steven Krakowka The Ohio State University
Daniel Todd
Daniel Todd Agri-Food and Biosciences Institute
Anette Bøtner
Anette Bøtner University of Copenhagen
Per Wallgren
Per Wallgren National Veterinary Institute
John H. Harding
John H. Harding University of Sheffield
Averil E. Brown
Averil E. Brown Queen's University Belfast
Alexander McPherson
Alexander McPherson University of California, Irvine

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