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Biology and Biochemistry

D-Index
51
Citations
20500
World Ranking
16922
National Ranking
1219

Overview

Hiroyuki Sasaki is affiliated with the Jikei University School of Medicine in Japan. Their research spans primarily the field of Medicine, with a focus on subfields including Physiology, Endocrine and Autonomic Systems, Experimental and Cognitive Psychology, Molecular Biology, and Psychiatry and Mental Health. Sasaki's work covers a broad spectrum of topics within these fields.

The main topics of their research include:

  • Dietary Effects on Health
  • Diet and metabolism studies
  • Circadian rhythm and melatonin
  • Tryptophan and brain disorders
  • Gastrointestinal motility and disorders
  • Sleep and related disorders
  • Attention Deficit Hyperactivity Disorder

Frequent venues where Sasaki has published research are:

  • Nutrients
  • Kidney International
  • Metabolites
  • Scientific Reports
  • Frontiers in Nutrition

Some notable recent papers attributed to Sasaki's collaborative network include:

  • The circadian clock is disrupted in mice with adenine-induced tubulointerstitial nephropathy, 2020, Kidney International
  • Solid-State Fermented Okara with Aspergillus spp. Improves Lipid Metabolism and High-Fat Diet Induced Obesity, 2022, Metabolites
  • Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency, centromeric instability and facial anomalies syndrome with distinctive genome-wide DNA hypomethylation, 2022, Human Molecular Genetics
  • Gamma Oryzanol Alleviates High-Fat Diet-Induced Anxiety-Like Behaviors Through Downregulation of Dopamine and Inflammation in the Amygdala of Mice, 2020, Frontiers in Pharmacology
  • Effects of Timing of Acute and Consecutive Catechin Ingestion on Postprandial Glucose Metabolism in Mice and Humans, 2020, Nutrients

Frequent coauthors who have collaborated extensively with Sasaki include:

  • Shigenobu Shibata
  • Atsushi Haraguchi
  • Yijin Lyu
  • Hiroki Miyakawa
  • Momoko Imamura

Best Publications

  • Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice

    Takehiro Nitta;Masaki Hata;Shimpei Gotoh;Yoshiteru Seo

  • Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

    Mitinori Saitou;Mikio Furuse;Hiroyuki Sasaki;Jörg-Dieter Schulzke

  • A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts.

    Mikio Furuse;Hiroyuki Sasaki;Kazushi Fujimoto;Shoichiro Tsukita

  • Endothelial Claudin: Claudin-5/Tmvcf Constitutes Tight Junction Strands in Endothelial Cells

    Kazumasa Morita;Hiroyuki Sasaki;Mikio Furuse;Shoichiro Tsukita

  • Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands

    Mikio Furuse;Hiroyuki Sasaki;Shoichiro Tsukita

  • Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.

    Mikio Furuse;Kyoko Furuse;Hiroyuki Sasaki;Shoichiro Tsukita

  • ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation

    Kazuaki Umeda;Junichi Ikenouchi;Sayaka Katahira-Tayama;Kyoko Furuse

  • Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

    Junichi Ikenouchi;Mikio Furuse;Kyoko Furuse;Hiroyuki Sasaki

  • Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.

    Noriyuki Sonoda;Mikio Furuse;Hiroyuki Sasaki;Shigenobu Yonemura

  • Claudin-11/OSP-based Tight Junctions of Myelin Sheaths in Brain and Sertoli Cells in Testis

    Kazumasa Morita;Hiroyuki Sasaki;Kazushi Fujimoto;Mikio Furuse

  • External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers

    Akiharu Kubo;Keisuke Nagao;Mariko Yokouchi;Hiroyuki Sasaki;Hiroyuki Sasaki

  • Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions

    Masahiko Itoh;Hiroyuki Sasaki;Mikio Furuse;Harunobu Ozaki

  • Multi-PDZ Domain Protein 1 (MUPP1) Is Concentrated at Tight Junctions through Its Possible Interaction with Claudin-1 and Junctional Adhesion Molecule

    Yoko Hamazaki;Masahiko Itoh;Hiroyuki Sasaki;Mikio Furuse

  • CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

    Yuko Mimori-Kiyosue;Ilya Grigoriev;Gideon Lansbergen;Hiroyuki Sasaki

  • Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

    Hideki Sumimoto;Youhko Kage;Hiroyuki Nunoi;Hiroyuki Sasaki

  • Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis.

    Akiharu Kubo;Hiroyuki Sasaki;Akiko Yuba-Kubo;Shoichiro Tsukita

  • Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions.

    David R. Raleigh;Amanda M. Marchiando;Yong Zhang;Le Shen

  • Establishment and Characterization of Cultured Epithelial Cells Lacking Expression of ZO-1 *

    Kazuaki Umeda;Takeshi Matsui;Mayumi Nakayama;Kyoko Furuse

  • Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules

    Shigeaki Muto;Masaki Hata;Junichi Taniguchi;Shuichi Tsuruoka

  • Specificity and biomineralization activities of Ti-binding peptide-1 (TBP-1).

    Ken-Ichi Sano;Hiroyuki Sasaki;Kiyotaka Shiba

Frequent Co-Authors

Shoichiro Tsukita
Shoichiro Tsukita Kyoto University
Mikio Furuse
Mikio Furuse The Graduate University for Advanced Studies, SOKENDAI
Sachiko Tsukita
Sachiko Tsukita Osaka University
Clara Franzini-Armstrong
Clara Franzini-Armstrong University of Pennsylvania
Kiyotaka Shiba
Kiyotaka Shiba Japanese Foundation For Cancer Research
Yale E. Goldman
Yale E. Goldman University of Pennsylvania
Dora Brites
Dora Brites University of Lisbon
Takuya Yamamoto
Takuya Yamamoto Kyoto University
Jun Liu
Jun Liu Yale University
Anna Akhmanova
Anna Akhmanova Utrecht University

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