2026 Christina M. Van Itallie: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	43	2952	2683	1408	1265	67	12021

Overview

Christina M. Van Itallie is a researcher affiliated with the National Institutes of Health in the United States. Their work spans key areas in medicine and neuroscience with a focus on neurology and molecular biology as well as physiology, cell biology, and pulmonary and respiratory medicine.

Their research includes investigations into barrier structure and function, neurological disease mechanisms and treatments, skin and cellular biology, sarcoma diagnosis and treatment, cell adhesion molecules, Clostridium difficile and Clostridium perfringens, and gut microbiota and health.

Several recent publications by Christina M. Van Itallie demonstrate their active engagement in these fields. Notable papers include:

Biotin ligase tagging identifies proteins proximal to E-cadherin, including lipoma preferred partner, a regulator of epithelial cell-cell and cell-substrate adhesion (2021, UNC Libraries)
Structure of the Claudin-binding Domain of Clostridium perfringens Enterotoxin (2021, UNC Libraries)
Physiology and Function of the Tight Junction (2020, UNC Libraries)
Claudin-2 Forms Homodimers and Is a Component of a High Molecular Weight Protein Complex (2020, UNC Libraries)
Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins (2020, UNC Libraries)

Christina M. Van Itallie has frequently collaborated with several researchers, including:

James M. Anderson
Alan S. Fanning
Arlene S. Bridges
Jennifer L. Holmes

Their work has been primarily published in the venue UNC Libraries where they have contributed to at least eleven publications.

Best Publications

Claudins and epithelial paracellular transport.

Christina M. Van Itallie;James M. Anderson

1312
Citations
Physiology and Function of the Tight Junction

Anderson Jm;Van Itallie Cm

1186
Citations
Tight junctions and the molecular basis for regulation of paracellular permeability

J. M. Anderson;C. M. Van Itallie

1161
Citations
Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability

Christina Van Itallie;Christoph Rahner;James Melvin Anderson

712
Citations
Claudins create charge-selective channels in the paracellular pathway between epithelial cells.

Oscar R. Colegio;Christina M. Van Itallie;Heather J. McCrea;Christoph Rahner

643
Citations
Architecture of tight junctions and principles of molecular composition

Christina M. Van Itallie;James M. Anderson

595
Citations
Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins.

Laura L. Mitic;Christina M. Van Itallie;James M. Anderson

594
Citations
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2.

Christina M. Van Itallie;Jennifer Holmes;Arlene Bridges;Jody L. Gookin

539
Citations
Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture.

Oscar R. Colegio;Christina Van Itallie;Christoph Rahner;James Melvin Anderson

535
Citations
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton.

Christina M. Van Itallie;Alan S. Fanning;Arlene Bridges;James M. Anderson

461
Citations
Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins

Christina M. Van Itallie;Alan S. Fanning;James M. Anderson

442
Citations
Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

Tamar Ben-Yosef;Inna A. Belyantseva;Thomas L. Saunders;Elizabeth D. Hughes

421
Citations
The Molecular Physiology of Tight Junction Pores

Christina M. Van Itallie;James Melvin Anderson

421
Citations
Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns

Jennifer L. Holmes;Christina M. Van Itallie;Julia E. Rasmussen;James M. Anderson

388
Citations
Occludin confers adhesiveness when expressed in fibroblasts

C.M. Van Itallie;J.M. Anderson

386
Citations
Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities

Christina M. Van Itallie;Sarah Rogan;Alan Yu;Lucia Seminario Vidal

311
Citations
Setting up a selective barrier at the apical junction complex.

James Melvin Anderson;Christina M Van Itallie;Alan S Fanning

281
Citations
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia.

Alan S. Fanning;Christina M. Van Itallie;James M. Anderson

273
Citations
Transforming growth factor beta1 modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis

June Rae Merwin;James M. Anderson;Olivier Kocher;Christina M. Van Itallie

266
Citations
Occludin is required for cytokine-induced regulation of tight junction barriers

Christina M. Van Itallie;Alan S. Fanning;Jennifer Holmes;James M. Anderson

229
Citations

Frequent Co-Authors

James M. Anderson National Institutes of Health

Bechara Kachar National Institutes of Health

Bruce A. McClane University of Pittsburgh

Andrew Forge University College London

Inna A. Belyantseva National Institutes of Health

Sherri M. Jones University of Nebraska–Lincoln

Yehoash Raphael University of Michigan–Ann Arbor

Saima Riazuddin University of Maryland, Baltimore

Thomas B. Friedman National Institutes of Health

Sally A. Camper University of Michigan–Ann Arbor

External Links

Personal website of Christina M. Van Itallie

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