World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
19033
World Ranking
8111
National Ranking
628

Overview

Karl Matter is affiliated with University College London in the United Kingdom and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work extensively covers molecular and cell biology with significant contributions to neurology, ophthalmology, and immunology and allergy research.

The scientist's research delves into topics including barrier structure and function studies, Hippo pathway signaling and YAP/TAZ, S100 proteins and annexins, connexins and lens biology, cellular transport and secretion, glaucoma and retinal disorders, and cell adhesion molecules research. This range of topics outlines a broad interest in cellular mechanisms and the structural and functional properties of biological barriers and signaling pathways.

Recent publications include:

  • Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly (2020, Cell Reports)
  • ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions (2022, Cells)
  • Tight junctions (2023, Current Biology)
  • Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function (2021, Scientific Reports)
  • Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis (2022, The Journal of Cell Biology)

Frequent co-authors of Karl Matter include María S. Balda, Ceniz Zihni, A Haas, James Bainbridge, and Anastasios Georgiadis. This network indicates collaboration across multiple aspects of cell biology and molecular research.

Karl Matter publishes often in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cells, The Journal of Cell Biology, Cell Reports, and Current Biology, reflecting active engagement in the cell biology and molecular biosciences research community.

Best Publications

  • Tight junctions: from simple barriers to multifunctional molecular gates

    Ceniz Zihni;Clare Mills;Karl Matter;Maria S. Balda

  • Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.

    M S Balda;J A Whitney;C Flores;S González

  • Signalling to and from tight junctions

    Karl Matter;Maria S. Balda

  • The tight junction protein ZO‐1 and an interacting transcription factor regulate ErbB‐2 expression

    Maria S. Balda;Karl Matter

  • MECHANISMS OF CELL POLARITY : SORTING AND TRANSPORT IN EPITHELIAL CELLS

    Karl Matter;Ira Mellman

  • ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

    Olga Tornavaca;Minghao Chia;Neil Dufton;Lourdes Osuna Almagro

  • Dynamics and functions of tight junctions

    Emily Steed;Maria S. Balda;Karl Matter

  • Assembly of the tight junction: the role of diacylglycerol.

    M S Balda;L Gonzalez-Mariscal;K Matter;M Cereijido

  • The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density.

    Maria S. Balda;Michelle D. Garrett;Karl Matter

  • Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants.

    Karl Matter;Walter Hunziker;Ira Mellman

  • Tight Junctions: Molecular Architecture and Function

    Saima Aijaz;Maria S Balda;Karl Matter

  • Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

    Walter Hunziker;Cordula Harter;Karl Matter;Ira Mellman

  • Mammalian tight junctions in the regulation of epithelial differentiation and proliferation.

    Karl Matter;Saima Aijaz;Anna Tsapara;Maria S Balda

  • Functional analysis of tight junctions.

    Karl Matter;Maria S. Balda

  • Tight junctions and the regulation of gene expression.

    Maria S. Balda;Karl Matter

  • Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells.

    Karl Matter;Ellen M. Yamamoto;Ira Mellman

  • Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2)

    Karl Matter;Mathis Brauchbar;Kaethy Bucher;Hans-Peter Hauri

  • Identification of an intermediate compartment involved in protein transport from endoplasmic reticulum to Golgi apparatus.

    A. Schweizer;J. A. M. Fransen;K. Matter;T. E. Kreis

  • Biogenesis of tight junctions: the C-terminal domain of occludin mediates basolateral targeting

    K. Matter;M.S. Balda

  • Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis.

    Stephen J. Terry;Ceniz Zihni;Ahmed Elbediwy;Elisa Vitiello

Frequent Co-Authors

Maria S. Balda
Maria S. Balda University College London
Ira Mellman
Ira Mellman Parker Institute for Cancer Immunotherapy
Anand Swaroop
Anand Swaroop National Institutes of Health
Shomi S. Bhattacharya
Shomi S. Bhattacharya University College London
Walter Hunziker
Walter Hunziker Agency for Science, Technology and Research
Robin R. Ali
Robin R. Ali King's College London
James M. Anderson
James M. Anderson National Institutes of Health
Michael E. Cheetham
Michael E. Cheetham University College London
Anthony T. Moore
Anthony T. Moore University of California, San Francisco
John Greenwood
John Greenwood University College London

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