Her primary areas of study are Tight junction, Cell biology, Claudin, Paracellular transport and Occludin. The Tight junction study combines topics in areas such as Barrier function, Cell signaling, Desmosome and Cadherin. Her Cell biology study integrates concerns from other disciplines, such as Membrane protein and Nephron.
Her biological study spans a wide range of topics, including Epithelium, Reabsorption, Transfection, Molecular biology and Endoplasmic reticulum. Her study on Paracellular transport is covered under Permeability. Her Occludin research is multidisciplinary, relying on both Confocal microscopy, Apoptosis and Fluorescence recovery after photobleaching.
Her primary areas of investigation include Tight junction, Paracellular transport, Claudin, Biophysics and Cell biology. Occludin is the focus of her Tight junction research. She combines subjects such as Endocrinology, Transcellular, Internal medicine and Loop of Henle with her study of Paracellular transport.
Her work on CLDN3 as part of general Claudin research is frequently linked to Water transport, bridging the gap between disciplines. Dorothee Günzel interconnects Membrane, Biochemistry, Ion transporter, HEK 293 cells and Ion channel in the investigation of issues within Biophysics. Dorothee Günzel has researched Cell biology in several fields, including Membrane protein, Cell, Tight junction permeability and Actin cytoskeleton.
The scientist’s investigation covers issues in Claudin, Tight junction, Paracellular transport, Biophysics and Cell biology. She focuses mostly in the field of Claudin, narrowing it down to topics relating to Molecular biology and, in certain cases, Stop codon. Her study in Tight junction is interdisciplinary in nature, drawing from both Extracellular, Cell and Tubule.
Dorothee Günzel has included themes like Ion homeostasis and Transcellular in her Paracellular transport study. Her Biophysics research includes themes of Biochemistry, Permeability, HEK 293 cells, Ion channel and CLDN3. Her study looks at the relationship between Cell biology and topics such as Small intestine, which overlap with Proinflammatory cytokine.
Dorothee Günzel mostly deals with Claudin, Paracellular transport, Tight junction, Biophysics and Biochemistry. Her Claudin study frequently links to adjacent areas such as Reabsorption. Her work investigates the relationship between Paracellular transport and topics such as Transcellular that intersect with problems in Matrix, Inner ear and Extracellular.
Her HEK 293 cells research extends to Tight junction, which is thematically connected. Her research integrates issues of Cell junction, Cell membrane, Ion channel and Permeability in her study of Biophysics. Her Transmembrane protein, Occludin and Incubation study in the realm of Biochemistry connects with subjects such as Short-chain fatty acid.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease
Sebastian Zeissig;Nataly Bürgel;Dorothee Günzel;Jan Richter.
Claudins and the Modulation of Tight Junction Permeability
Dorothee Günzel;Alan S. L. Yu.
Physiological Reviews (2013)
E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions
Judith A Tunggal;Iris Helfrich;Annika Schmitz;Heinz Schwarz.
The EMBO Journal (2005)
Claudin-2, a component of the tight junction, forms a paracellular water channel.
Rita Rosenthal;Susanne Milatz;Susanne M. Krug;Beibei Oelrich.
Journal of Cell Science (2010)
Microbial butyrate and its role for barrier function in the gastrointestinal tract
Svenja Plöger;Friederike Stumpff;Gregory B. Penner;Jörg-Dieter Schulzke.
Annals of the New York Academy of Sciences (2012)
Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability
Susanne M. Krug;Salah Amasheh;Jan F. Richter;Susanne Milatz.
Molecular Biology of the Cell (2009)
Claudins and other tight junction proteins.
Dorothee Günzel;Michael Fromm.
Comprehensive Physiology (2012)
Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site.
Alan S.L. Yu;Mary H. Cheng;Susanne Angelow;Dorothee Günzel.
The Journal of General Physiology (2009)
Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes.
Susanne Milatz;Susanne M. Krug;Rita Rosenthal;Dorothee Günzel.
Biochimica et Biophysica Acta (2010)
Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin-16
P. Jaya Kausalya;Salah Amasheh;Dorothee Günzel;Henrik Wurps.
Journal of Clinical Investigation (2006)
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