What is he best known for?
The fields of study he is best known for:
His main research concerns Cell biology, Molecular biology, Tight junction, Occludin and Catenin.
The various areas that Otmar Huber examines in his Cell biology study include Bone morphogenetic protein 5, Bone morphogenetic protein and Adherens junction.
His Molecular biology study incorporates themes from Cadherin, Wnt signaling pathway, Transcription factor, Transfection and Neuroepithelial cell.
Otmar Huber focuses mostly in the field of Wnt signaling pathway, narrowing it down to matters related to Transactivation and, in some cases, Beta-catenin and Cell membrane.
The study incorporates disciplines such as Embryonic stem cell and Cell culture in addition to Transcription factor.
His work on Claudin as part of general Tight junction study is frequently connected to Tricellular tight junction and Paracellular transport, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His most cited work include:
- Nuclear localization of β-catenin by interaction with transcription factor LEF-1 (814 citations)
- E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation (462 citations)
- Cadherins and catenins in development (321 citations)
What are the main themes of his work throughout his whole career to date?
Otmar Huber focuses on Cell biology, Molecular biology, Wnt signaling pathway, Tight junction and Occludin.
His Cell biology research includes elements of Cadherin, Adherens junction and Transmembrane protein.
The Molecular biology study combines topics in areas such as Cell, Cell cycle, Enhancer, Transcription and Cell adhesion molecule.
His research integrates issues of Cancer research, Transcription factor and FHIT in his study of Wnt signaling pathway.
His Tight junction course of study focuses on Macromolecule and Ultrastructure.
His Occludin research focuses on subjects like Phosphorylation, which are linked to Sequence motif and Bioinformatics.
He most often published in these fields:
- Cell biology (65.42%)
- Molecular biology (28.04%)
- Wnt signaling pathway (22.43%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (65.42%)
- Pathology (4.67%)
- Wnt signaling pathway (22.43%)
In recent papers he was focusing on the following fields of study:
Otmar Huber mainly focuses on Cell biology, Pathology, Wnt signaling pathway, Internal medicine and Cancer research.
His Cell biology research is mostly focused on the topic Tight junction.
His Pathology research incorporates themes from Hepatocyte, Organoid and Monocyte.
His studies deal with areas such as Cell junction, Adherens junction, Desmoplakin and Cell growth as well as Wnt signaling pathway.
His studies examine the connections between Internal medicine and genetics, as well as such issues in Endocrinology, with regards to Fructose.
His study looks at the relationship between Cancer research and topics such as Trefoil factor 3, which overlap with Molecular biology, Colon carcinoma, Regulatory rna, microRNA and RNA interference.
Between 2014 and 2021, his most popular works were:
- A microfluidically perfused three dimensional human liver model. (93 citations)
- Diets rich in fructose, fat or fructose and fat alter intestinal barrier function and lead to the development of nonalcoholic fatty liver disease over time (87 citations)
- Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions. (41 citations)
In his most recent research, the most cited papers focused on:
Pathology, Cell biology, Monocyte, Biochip and Inflammation are his primary areas of study.
He has researched Pathology in several fields, including Organoid and Hepatocyte.
His study in Wnt signaling pathway and Signal transduction falls under the purview of Cell biology.
His Monocyte research is multidisciplinary, incorporating perspectives in Human liver and Receptor.
His Biochip study combines topics from a wide range of disciplines, such as Viability assay, Cell culture, In vitro, Cell adhesion molecule and Cytoskeleton.
His Inflammation research includes themes of Innate immune system, Immune system and Microbiology, Candida albicans.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
