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Biology and Biochemistry

D-Index
67
Citations
15428
World Ranking
8243
National Ranking
3727

Overview

Michael Harris is a researcher affiliated with the University of Florida in the United States. Their academic contributions primarily focus on biochemistry, genetics, and molecular biology, with a particular emphasis on molecular biology as reflected in their publications.

Their recent published works include a range of studies in various respected scientific journals. Notable papers are:

  • Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P, 2022, Nature Communications
  • Kinetic analysis of RNA cleavage by coronavirus Nsp15 endonuclease: Evidence for acid-base catalysis and substrate-dependent metal ion activation, 2023, Journal of Biological Chemistry
  • Dissociative Transition State in Hepatitis Delta Virus Ribozyme Catalysis, 2023, Journal of the American Chemical Society
  • Atomic-Scale View of Protein-PEG Interactions that Redirect the Thermal Unfolding Pathway of PEGylated Human Galectin-3, 2022, Angewandte Chemie International Edition
  • The specificity landscape of bacterial ribonuclease P, 2023, Journal of Biological Chemistry

Michael Harris has collaborated frequently with several coauthors, including:

  • Darrin M. York
  • Joseph A. Piccirilli
  • Alexandra R. Chamberlain
  • Amanda Pritzlaff
  • Guillaume Ferré

The scientist's research has been published extensively in the following venues:

  • Faraday Discussions
  • Journal of Biological Chemistry
  • Biochemistry
  • Nature Communications
  • Journal of the American Chemical Society

The main fields of study covered by Michael Harris include biochemistry, genetics, and molecular biology, with a specific concentration on molecular biology. Subfields they explore are:

  • Molecular Biology
  • Immunology
  • Ecology
  • Genetics
  • Infectious Diseases

Their research topics engage various aspects of biological and biochemical mechanisms, including:

  • RNA and protein synthesis mechanisms
  • DNA and Nucleic Acid Chemistry
  • Bacteriophages and microbial interactions
  • Advanced biosensing and bioanalysis techniques
  • Galectins and Cancer Biology
  • Toxin Mechanisms and Immunotoxins
  • Bacterial Genetics and Biotechnology

Best Publications

  • Osteosarcoma: The Addition of Muramyl Tripeptide to Chemotherapy Improves Overall Survival—A Report From the Children's Oncology Group

    Paul A. Meyers;Cindy L. Schwartz;Mark D. Krailo;John H. Healey

  • Osteosarcoma: A Randomized, Prospective Trial of the Addition of Ifosfamide and/or Muramyl Tripeptide to Cisplatin, Doxorubicin, and High-Dose Methotrexate

    Paul A. Meyers;Cindy L. Schwartz;Mark Krailo;Eugenie S. Kleinerman

  • Presurgical Chemotherapy Compared With Immediate Surgery and Adjuvant Chemotherapy for Nonmetastatic Osteosarcoma: Pediatric Oncology Group Study POG-8651

    Allen M. Goorin;Douglas J. Schwartzentruber;Meenakshi Devidas;Mark C. Gebhardt

  • Phase II Study of Nelarabine (compound 506U78) in Children and Young Adults With Refractory T-Cell Malignancies: A Report From the Children’s Oncology Group

    Stacey L. Berg;Susan M. Blaney;Meenakshi Devidas;Tom A. Lampkin

  • Defects in Breathing and Thermoregulation in Mice with Near-Complete Absence of Central Serotonin Neurons

    Matthew R. Hodges;Glenn J. Tattersall;Michael B. Harris;Sean D. McEvoy

  • Cyclophosphamide Plus Topotecan in Children With Recurrent or Refractory Solid Tumors: A Pediatric Oncology Group Phase II Study

    R L Saylors rd;K C Stine;J Sullivan;J L Kepner

  • Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.

    Y Ravindranath;E Abella;JP Krischer;J Wiley

  • Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps.

    Michael E. Harris;Ruth Böhni;Martin H. Schneiderman;Lakshman Ramamurthy

  • Ploidy of lymphoblasts is the strongest predictor of treatment outcome in B-progenitor cell acute lymphoblastic leukemia of childhood: a Pediatric Oncology Group study.

    R Trueworthy;J Shuster;T Look;W Crist

  • Phase II/III Trial of Etoposide and High-Dose Ifosfamide in Newly Diagnosed Metastatic Osteosarcoma: A Pediatric Oncology Group Trial

    Allen M. Goorin;Michael B. Harris;Mark Bernstein;William Ferguson

  • Specificity and nonspecificity in RNA-protein interactions.

    Eckhard Jankowsky;Michael E. Harris

  • Trisomy of leukemic cell chromosomes 4 and 10 identifies children with B-progenitor cell acute lymphoblastic leukemia with a very low risk of treatment failure: a Pediatric Oncology Group study.

    MB Harris;JJ Shuster;A Carroll;AT Look

  • Use of photoaffinity crosslinking and molecular modeling to analyze the global architecture of ribonuclease P RNA

    Michael E. Harris;James M. Nolan;Arun Malhotra;Arun Malhotra;James W. Brown;James W. Brown

  • Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.

    H. Stacy Nicholson;Cynthia S. Kretschmar;Mark Krailo;Mark Bernstein

  • Effects of different forms of central nervous system prophylaxis on neuropsychologic function in childhood leukemia.

    J H Rowland;O J Glidewell;R F Sibley;J C Holland

  • Comparison of Intermediate-Dose Methotrexate with Cranial Irradiation for the Post-Induction Treatment of Acute Lymphocytic Leukemia in Children

    Freeman Ai;Weinberg;Brecher Ml;Jones B

  • Treatment of metastatic osteosarcoma at diagnosis: a Pediatric Oncology Group Study.

    Michael B. Harris;Peter Gieser;Allen M. Goorin;Alberto Ayala

  • Central nervous system regulation of mammalian hibernation: implications for metabolic suppression and ischemia tolerance

    Kelly L. Drew;C. Loren Buck;Brian M. Barnes;Sherri L. Christian

  • Quantitative blood cultures in the evaluation of septicemia in children with Broviac catheters

    Harold S. Raucher;Alexander C. Hyatt;Asher Barzilai;Michael B. Harris

  • Native mRNA editing complexes from Trypanosoma brucei mitochondria.

    Victoria W. Pollard;Michael E. Harris;Stephen L. Hajduk

Frequent Co-Authors

Darrin M. York
Darrin M. York Rutgers, The State University of New Jersey
Vernon E. Anderson
Vernon E. Anderson Case Western Reserve University
Joseph A. Piccirilli
Joseph A. Piccirilli University of Chicago
George B. Richerson
George B. Richerson University of Iowa
John E. Remmers
John E. Remmers University of Calgary
Stephen L. Hajduk
Stephen L. Hajduk University of Georgia
Norman R. Pace
Norman R. Pace University of Colorado Boulder
Eckhard Jankowsky
Eckhard Jankowsky Case Western Reserve University
Holcombe E. Grier
Holcombe E. Grier Harvard University
Michael P. Link
Michael P. Link Stanford University

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