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90
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27671
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12271
National Ranking
6285

Overview

Paul S. Gaynon is a researcher affiliated with the University of Southern California in the United States. Their work is primarily situated within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on Public Health, Environmental and Occupational Health, Molecular Biology, Hematology, Pediatrics, Perinatology and Child Health, and Genetics.

The scientist's research centers on multiple aspects of leukemia and pediatric oncology. Main topics covered include:

  • Acute Lymphoblastic Leukemia research
  • Childhood Cancer Survivors' Quality of Life
  • Acute Myeloid Leukemia Research
  • Chronic Lymphocytic Leukemia Research
  • Neuroblastoma Research and Treatments
  • PI3K/AKT/mTOR signaling in cancer
  • Cancer therapeutics and mechanisms

Paul S. Gaynon has contributed to scientific literature with a number of recent papers. Noteworthy publications include:

  • Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study (2020), Clinical Cancer Research
  • Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR) (2022), Pediatric Blood & Cancer
  • A phase I study of panobinostat in children with relapsed and refractory hematologic malignancies (2020), Pediatric Hematology and Oncology
  • Temsirolimus combined with cyclophosphamide and etoposide for pediatric patients with relapsed/refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium trial (TACL 2014-001) (2022), Haematologica
  • Outcome of Infants Treated on Total Therapy for Infants with Acute Lymphoblastic Leukemia I: Results from a Non-Randomized Multi-Center Study (2023), Blood

The researcher frequently publishes in several key venues related to hematologic and pediatric oncology research. These include:

  • Blood
  • Pediatric Blood & Cancer
  • Clinical Cancer Research
  • Haematologica
  • Pediatric Hematology and Oncology

Collaborations are evident in their work, with frequent co-authors including Alexandra E. Kovach, Richard Sposto, Deepa Bhojwani, Jemily Malvar, and Andrew Doan. These collaborations reflect an interdisciplinary approach spanning clinical and molecular research domains.

Best Publications

  • Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group

    Stephen P. Hunger;Xiaomin Lu;Meenakshi Devidas;Bruce M. Camitta

  • Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia.

    M Smith;D Arthur;B Camitta;A J Carroll

  • Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

    Kirk R. Schultz;W. Paul Bowman;Alexander Aledo;William B. Slayton

  • Outcome of treatment in children with philadelphia chromosome-positive acute lymphoblastic leukemia

    M Arico;MG Valsecchi;B Camitta;M Schrappe

  • What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies.

    Wendy Stock;Mei La;Ben Sanford;Clara D. Bloomfield

  • Factors Influencing Survival After Relapse From Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

    Kim Nguyen;Meenakshi Devidas;Su-Chun Cheng;Mei La

  • A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a children's Cancer Group Study

    Vassilios I. Avramis;Susan Sencer;Antonia P. Periclou;Harland Sather

  • Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG)

    Kirk R. Schultz;D. Jeanette Pullen;Harland N. Sather;Jonathan J. Shuster

  • Augmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapy.

    James B. Nachman;Harland N. Sather;Martha G. Sensel;Michael E. Trigg

  • Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region

    Ching-Hon Pui;Paul S Gaynon;James M Boyett;Judith M Chessells

  • Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group study AALL0031.

    K. R. Schultz;A. Carroll;N. A. Heerema;W. P. Bowman

  • Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group.

    Bruce C. Bostrom;Martha R. Sensel;Harland N. Sather;Paul S. Gaynon

  • Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983-1995.

    PS Gaynon;ME Trigg;NA Heerema;MG Sensel

  • Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia

    Sima Jeha;Bassem Razzouk;Michael E Rytting;Susan Rheingold

  • Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group

    Nita L. Seibel;Peter G. Steinherz;Harland N. Sather;James B. Nachman

  • Long Term Results of the Children’s Cancer Group Studies for Childhood Acute Lymphoblastic Leukemia 1983–2002: a Children’s Oncology Group Report

    Paul S. Gaynon;Paul S. Gaynon;Anne L. Angiolillo;William L. Carroll;James B. Nachman

  • Survival after Relapse in Childhood Acute Lymphoblastic Leukemia Impact of Site and Time to First Relapse — the Children's Cancer Group Experience

    Paul S. Gaynon;Roger P. Qu;Richard J. Chappell;Michael L. N. Willoughby

  • Phase II Study of Nelarabine (compound 506U78) in Children and Young Adults With Refractory T-Cell Malignancies: A Report From the Children’s Oncology Group

    Stacey L. Berg;Susan M. Blaney;Meenakshi Devidas;Tom A. Lampkin

  • Outcomes after Induction Failure in Childhood Acute Lymphoblastic Leukemia

    Martin Schrappe;Stephen P. Hunger;Ching Hon Pui;Vaskar Saha

  • Outcome of Patients Treated for Relapsed or Refractory Acute Lymphoblastic Leukemia: A Therapeutic Advances in Childhood Leukemia Consortium Study

    Richard H. Ko;Lingyun Ji;Phillip Barnette;Bruce Bostrom

Frequent Co-Authors

Harland N. Sather
Harland N. Sather University of Southern California
Fatih M. Uckun
Fatih M. Uckun University of Southern California
Nyla A. Heerema
Nyla A. Heerema The Ohio State University
Richard Sposto
Richard Sposto University of Southern California
Stephen P. Hunger
Stephen P. Hunger University of Pennsylvania
Meenakshi Devidas
Meenakshi Devidas St. Jude Children's Research Hospital
William L. Carroll
William L. Carroll New York University
Bruce M. Camitta
Bruce M. Camitta Medical College of Wisconsin
Naomi J. Winick
Naomi J. Winick The University of Texas Southwestern Medical Center
Elizabeth A. Raetz
Elizabeth A. Raetz New York University

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