Lawrence R. Gahan

Overview

Best Publications

• The catalytic mechanisms of binuclear metallohydrolases.

  Natasa Mitic;Sarah J. Smith;Ademir Neves;Luke W. Guddat

  502
  Citations

• Phosphate forms an unusual tripodal complex with the Fe–Mn center of sweet potato purple acid phosphatase

  Gerhard Schenk;Lawrence R. Gahan;Lyle E. Carrington;Natas ÿa Mitic

  175
  Citations

• crystal Structure and Electrospray Ionization Mass Spectrometry, Electron Paramagnetic Resonance, and Magnetic Susceptibility Study of [Cu2(ascidH2)(1,2-.mu.-CO3)(H2O)2].cntdot.2H2O, the Bis(copper(II)) Complex of Ascidiacyclamide (ascidH4), a Cyclic Peptide Isolated from the Ascidian Lissoclinum patella

  Anna L. van den Brenk;Karl A. Byriel;David P. Fairlie;Lawrence R. Gahan

  172
  Citations

• Binuclear metallohydrolases: Complex mechanistic strategies for a simple chemical reaction

  Gerhard Schenk;Gerhard Schenk;Nataša Mitić;Lawrence R. Gahan;David L. Ollis

  159
  Citations

• Copper(II) complexes of the fluoroquinolone antimicrobial ciprofloxacin. Synthesis, X-ray structural characterization, and potentiometric study

  Steven C. Wallis;Lawrence R. Gahan;Bruce G. Charles;Trevor W. Hambley

  156
  Citations

• Five-coordinate transition metal complexes and the value of τ5: observations and caveats

  Allan G. Blackman;Elaine B. Schenk;Rebecca E. Jelley;Elizabeth H. Krenske

  156
  Citations

• Dinuclear Zinc(II) Complexes with Hydrogen Bond Donors as Structural and Functional Phosphatase Models

  Simone Bosch;Simone Bosch;Peter Comba;Lawrence R. Gahan;Gerhard Schenk

  114
  Citations

• Reactions of cisplatin hydrolytes with methionine, cysteine, and plasma ultrafiltrate studied by a combination of HPLC and NMR techniques

  Mahmoud El-Khateeb;Trevor G. Appleton;Lawrence R. Gahan;Bruce G. Charles

  113
  Citations

• Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle.

  Gerhard Schenk;Tristan W Elliott;Eleanor Leung;Lyle E Carrington

  107
  Citations

• Phosphate Ester Hydrolysis: Metal Complexes As Purple Acid Phosphatase and Phosphotriesterase Analogues

  Lawrence R. Gahan;Sarah J. Smith;Ademir Neves;Gerhard Schenk

  103
  Citations

• The organophosphate-degrading enzyme from Agrobacterium radiobacter displays mechanistic flexibility for catalysis.

  Fernanda Ely;Kieran S. Hadler;Lawrence R. Gahan;Luke W. Guddat

  102
  Citations

• Synthetic, EPR spectroscopic, magnetic and x-ray crystallographic structural studies on copper(II) complexes of the tridentate N2S donor ligand formed from 6-methyl-2-formylpyridine and S-methyldithiocarbazate (Hmpsme)

  Mohammad Akbar Ali;Aminul Huq Mirza;R J Fereday;Raymond J Butcher

  100
  Citations

• Organophosphate-degrading metallohydrolases: structure and function of potent catalysts for applications in bioremediation

  Gerhard Schenk;Irsa Mateen;Tee-Kheang Ng;Marcelo M. Pedroso

  98
  Citations

• A new heterobinuclear FeIIICuII complex with a single terminal FeIII–O(phenolate) bond. Relevance to purple acid phosphatases and nucleases

  Mauricio Lanznaster;Ademir Neves;Adailton J. Bortoluzzi;Veronika V. E. Aires

  97
  Citations

• Spectroscopic and Mechanistic Studies of Dinuclear Metallohydrolases and Their Biomimetic Complexes

  Lena J. Daumann;Gerhard Schenk;David L. Ollis;Lawrence R. Gahan

  96
  Citations

• Metal-Ion Mutagenesis: Conversion of a Purple Acid Phosphatase from Sweet Potato to a Neutral Phosphatase with the Formation of an Unprecedented Catalytically Competent MnIIMnII Active Site

  Natasa Mitić;Christopher J Noble;Lawrence R Gahan;Graeme R Hanson

  96
  Citations

• Encapsulated metal ions: synthesis, structure, and spectra of nitrogen-sulfur ligand atom cages containing cobalt(III) and cobalt(II)

  Lawrence R. Gahan;Trevor W. Hambley;Alan M. Sargeson;Michael R. Snow

  96
  Citations

• Electronic Structure and Spectro-Structural Correlations of FeIIIZnII Biomimetics for Purple Acid Phosphatases: Relevance to DNA Cleavage and Cytotoxic Activity

  Rosely A. Peralta;Adailton J. Bortoluzzi;Bernardo de Souza;Rafael Jovito

  95
  Citations

• Conformational Control by Thiazole and Oxazoline Rings in Cyclic Octapeptides of Marine Origin. Novel Macrocyclic Chair and Boat Conformations

  G. Abbenante;D. P. Fairlie;L. R. Gahan;G. R. Hanson

  95
  Citations

• Rhodium catalyzed template-assisted distal para-C–H olefination

  Uttam Dutta;Uttam Dutta;Uttam Dutta;Sudip Maiti;Sandeep Pimparkar;Sandeep Pimparkar;Sandeep Pimparkar;Siddhartha Maiti

  87
  Citations

• Development of hplc conditions for valid determination of hydrolysis products of cisplatin

  Mahmoud El-khateeb;Trevor G. Appleton;Bruce G. Charles;Lawrence R. Gahan

  85
  Citations