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Biology and Biochemistry

D-Index
57
Citations
16295
World Ranking
13604
National Ranking
131

Overview

Orly Reiner is affiliated with the Weizmann Institute of Science in Israel. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology as reflected in the predominance of publications in this subfield.

Their work covers several subfields, including molecular biology, cell biology, genetics, immunology, and biophysics. This breadth allows an interdisciplinary approach to their scientific inquiries.

Key topics explored in their research include pluripotent stem cells research, RNA research and splicing, RNA modifications and cancer, microtubule and mitosis dynamics, genetics and neurodevelopmental disorders, cell image analysis techniques, and epigenetics and DNA methylation.

Orly Reiner has published extensively, with a significant number of works appearing in prominent venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature, Oxford Open Neuroscience, and arXiv (Cornell University).

Notable recent papers authored or coauthored by Orly Reiner include:

  • A patterned human neural tube model using microfluidic gradients, 2024, Nature
  • A nomenclature consensus for nervous system organoids and assembloids, 2022, Nature
  • Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate, 2022, Nature Communications
  • International consensus recommendations on the diagnostic work-up for malformations of cortical development, 2020, Nature Reviews Neurology
  • Complement System in Brain Architecture and Neurodevelopmental Disorders, 2020, Frontiers in Neuroscience

The scientist often collaborates with other researchers. Frequent coauthors include Tamar Sapir, Tsviya Olender, Aditya Kshirsagar, Arpan Parichha, and Bidisha Bhattacharya, with collaborative counts ranging from six to fifteen joint publications.

Best Publications

  • Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

    Annemiske J.M.H. Verkerk;Maura Pieretti;James S. Sutcliffe;Ying-Hui Fu

  • Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons.

    Fiona Francis;Annette Koulakoff;Dominique Boucher;Philippe Chafey

  • Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats

    Orly Reiner;Romeo Carrozzo;Ying Shen;Manfred Wehnert

  • The human glucocerebrosidase gene and pseudogene : structure and evolution

    Mia Horowitz;Sylvia Wilder;Zeev Horowitz;Orly Reiner

  • Lissencephaly: A Human Brain Malformation Associated With Deletion of the LIS1 Gene Located at Chromosome 17p13

    William B. Dobyns;Orly Reiner;Romeo Carrozzo;David H. Ledbetter

  • Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit

    Tamar Sapir;Michael Elbaum;Orly Reiner

  • Human Brain Organoids on a Chip Reveal the Physics of Folding.

    Eyal Karzbrun;Aditya Kshirsagar;Sidney R. Cohen;Jacob H. Hanna

  • Doublecortin, a Stabilizer of Microtubules

    David Horesh;Tamar Sapir;Fiona Francis;Sharon Grayer Wolf

  • LIS1, CLIP-170's key to the dynein/dynactin pathway.

    Frédéric M. Coquelle;Michal Caspi;Fabrice P. Cordelières;Jim P. Dompierre

  • DCX, a new mediator of the JNK pathway

    Amos Gdalyahu;Indraneel Ghosh;Talia Levy;Tamar Sapir

  • Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit.

    Irene Garcia-Higuera;Jessica Fenoglio;Ying Li;Carol Lewis

  • Increased LIS1 expression affects human and mouse brain development

    Weimin Bi;Tamar Sapir;Oleg A. Shchelochkov;Feng Zhang

  • Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization.

    Aviv Cahana;Teresa Escamez;Richard S. Nowakowski;Nancy L. Hayes

  • Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression.

    Tianzhi Shu;Huang-Chun Tseng;Huang-Chun Tseng;Tamar Sapir;Patrick Stern

  • Interaction between LIS1 and doublecortin, two lissencephaly gene products

    Michal Caspi;Roee Atlas;Ayelet Kantor;Tamar Sapir

  • THE LISSENCEPHALY GENE PRODUCT LIS1, A PROTEIN INVOLVED IN NEURONAL MIGRATION, INTERACTS WITH A NUCLEAR MOVEMENT PROTEIN, NUDC

    S. M. Morris;U. Albrecht;O. Reiner;G. Eichele

  • The structure of the N-terminal domain of the product of the lissencephaly gene Lis1 and its functional implications.

    Myung Hee Kim;David R. Cooper;Arkadiusz Oleksy;Yancho Devedjiev

  • Doublecortin mutations cluster in evolutionarily conserved functional domains

    Tamar Sapir;David Horesh;Michal Caspi;Roee Atlas

  • The evolving doublecortin (DCX) superfamily

    Orly Reiner;Frédéric M Coquelle;Frédéric M Coquelle;Bastian Peter;Talia Levy

  • Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration

    O Reiner;U Albrecht;M Gordon;KA Chianese

Frequent Co-Authors

Salvador Martinez
Salvador Martinez Miguel Hernandez University
Junken Aoki
Junken Aoki Tohoku University
Susan K. McConnell
Susan K. McConnell Stanford University
Trent M. Woodruff
Trent M. Woodruff University of Queensland
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Sven Bergmann
Sven Bergmann Swiss Institute of Bioinformatics
Jamel Chelly
Jamel Chelly Institute of Genetics and Molecular and Cellular Biology
David H. Ledbetter
David H. Ledbetter University of Florida
James R. Lupski
James R. Lupski Baylor College of Medicine

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