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Biology and Biochemistry

D-Index
59
Citations
11694
World Ranking
12613
National Ranking
253

Overview

Luis Goya is affiliated with the Spanish National Research Council in Spain. Their research activity primarily focuses on the intersection of medicine, biochemistry, and molecular biology, with a notable emphasis on nutrition and dietetics as well as food science and organic chemistry subfields. The scientist's work covers a broad range of biochemical and molecular topics, particularly related to the effects of phytochemicals and antioxidant activities.

Their research contributions include the study of antioxidant activity and oxidative stress, edible oils quality and analysis, natural product bioactivities and synthesis, biochemical analysis and sensing techniques, fatty acid research and health, and tea polyphenols and effects. These topics reflect a multidisciplinary approach combining aspects of chemistry, biology, and nutrition science.

Recent publications by Luis Goya and their collaborators show a focus on understanding the biochemical and physiological roles of natural compounds, particularly those found in cocoa and other food sources. Selected recent papers include:

  • From Cocoa to Chocolate: Effect of Processing on Flavanols and Methylxanthines and Their Mechanisms of Action (2022, International Journal of Molecular Sciences)
  • Effect of Cocoa and Cocoa Products on Cognitive Performance in Young Adults (2020, Nutrients)
  • Physiological Doses of Oleic and Palmitic Acids Protect Human Endothelial Cells from Oxidative Stress (2022, Molecules)
  • Cocoa Flavanols Protect Human Endothelial Cells from Oxidative Stress (2020, Plant Foods for Human Nutrition)
  • Colonic Coffee Phenols Metabolites, Dihydrocaffeic, Dihydroferulic, and Hydroxyhippuric Acids Protect Hepatic Cells from TNF-α-Induced Inflammation and Oxidative Stress (2023, International Journal of Molecular Sciences)

Frequent co-authors collaborating with Luis Goya include:

  • Olga Palomino
  • Raquel Mateos
  • Sonia de Pascual-Teresa
  • María Ángeles Martín
  • María S. Fernández-Alfonso

The scientist regularly publishes in journals that specialize in nutrition and molecular sciences. Frequent publication venues are:

  • Nutrients
  • Molecules
  • International Journal of Molecular Sciences
  • Biomolecules
  • Plant Foods for Human Nutrition

Their publications span over 26 contributions in the field of medicine and 10 in biochemistry, genetics, and molecular biology, indicating a substantive body of work bridging health-related biochemical research and nutritional science.

Best Publications

  • Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum.

    M. K. Webster;L. Goya;Ying Ge;A. C. Maiyar

  • Determination of malondialdehyde (MDA) by high-performance liquid chromatography in serum and liver as a biomarker for oxidative stress: Application to a rat model for hypercholesterolemia and evaluation of the effect of diets rich in phenolic antioxidants from fruits

    Raquel Mateos;Elena Lecumberri;Sonia Ramos;Luis Goya

  • Quercetin Induces Apoptosis via Caspase Activation, Regulation of Bcl-2, and Inhibition of PI-3-Kinase/Akt and ERK Pathways in a Human Hepatoma Cell Line (HepG2)

    Ana Belén Granado-Serrano;María Angeles Martín;Laura Bravo;Luis Goya

  • LC/MS characterization of phenolic constituents of mate (Ilex paraguariensis, St. Hil.) and its antioxidant activity compared to commonly consumed beverages

    Laura Bravo;Luis Goya;Elena Lecumberri

  • Dietary fibre composition, antioxidant capacity and physico-chemical properties of a fibre-rich product from cocoa (Theobroma cacao L.)

    Elena Lecumberri;Raquel Mateos;María Izquierdo-Pulido;Pilar Rupérez

  • Effect of grape antioxidant dietary fiber on the total antioxidant capacity and the activity of liver antioxidant enzymes in rats

    Margarita Alía;César. Horcajo;Laura Bravo;Luis Goya

  • Quercetin protects human hepatoma HepG2 against oxidative stress induced by tert-butyl hydroperoxide

    Mario Alía;Sonia Ramos;Raquel Mateos;Ana Belén Granado-Serrano

  • Influence of quercetin and rutin on growth and antioxidant defense system of a human hepatoma cell line (HepG2).

    Mario Alía;Raquel Mateos;Sonia Ramos;Elena Lecumberri

  • Response of the antioxidant defense system to tert-butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2).

    Mario Alía;Sonia Ramos;Raquel Mateos;Laura Bravo

  • Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38

    Ana Belén Granado-Serrano;María Angeles Martín;Laura Bravo;Luis Goya

  • Effect of the olive oil phenol hydroxytyrosol on human hepatoma HepG2 cells: Protection against oxidative stress induced by tert-butylhydroperoxide

    Luis Goya;Raquel Mateos;Laura Bravo

  • Cocoa flavonoids up-regulate antioxidant enzyme activity via the ERK1/2 pathway to protect against oxidative stress-induced apoptosis in HepG2 cells

    María Ángeles Martín;Ana Belén Granado Serrano;Sonia Ramos;María Izquierdo Pulido

  • Comparative Effects of Food-Derived Polyphenols on the Viability and Apoptosis of a Human Hepatoma Cell Line (HepG2)

    Sonia Ramos;Margarita Alía;Laura Bravo;Luis Goya

  • Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells.

    Isabel Cordero-Herrera;María Ángeles Martín;Luis Goya;Sonia Ramos

  • Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells.

    María Angeles Martín;Sonia Ramos;Ana Belén Granado-Serrano;Ildefonso Rodríguez-Ramiro

  • Cocoa flavonoids improve insulin signalling and modulate glucose production via AKT and AMPK in HepG2 cells

    Isabel Cordero-Herrera;María Angeles Martín;Laura Bravo;Luis Goya

  • A diet rich in dietary fiber from cocoa improves lipid profile and reduces malondialdehyde in hypercholesterolemic rats.

    Elena Lecumberri;Luis Goya;Raquel Mateos;Mario Alía

  • Molecular mechanisms of (-)-epicatechin and chlorogenic acid on the regulation of the apoptotic and survival/proliferation pathways in a human hepatoma cell line.

    Ana Belén Granado-Serrano;María Angeles Martín;María Izquierdo-Pulido;Luis Goya

  • Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway.

    Ildefonso Rodríguez-Ramiro;Sonia Ramos;Laura Bravo;Luis Goya

  • Protection of human HepG2 cells against oxidative stress by cocoa phenolic extract.

    María Angeles Martín;Sonia Ramos;Raquel Mateos;Ana Belén Granado Serrano

Frequent Co-Authors

Sonia Ramos
Sonia Ramos Spanish National Research Council
Laura Bravo
Laura Bravo Spanish National Research Council
María Ángeles Martín
María Ángeles Martín Spanish National Research Council
Raquel Mateos
Raquel Mateos Spanish National Research Council
Alvaro Pascual-Leone
Alvaro Pascual-Leone Harvard University
Lucia Panzella
Lucia Panzella University of Naples Federico II
Alessandra Napolitano
Alessandra Napolitano University of Naples Federico II
Marco d'Ischia
Marco d'Ischia University of Naples Federico II
Carmen Cámara
Carmen Cámara Complutense University of Madrid
Blanca Hernández-Ledesma
Blanca Hernández-Ledesma Spanish National Research Council

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