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Inger Johansson

Inger Johansson

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
12815
World Ranking
9801
National Ranking
137

Overview

Inger Johansson is affiliated with the Karolinska Institute in Sweden and has an extensive research profile predominantly in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans a range of subfields including Pharmacology, Molecular Biology, Computational Theory and Mathematics, Endocrinology, Diabetes and Metabolism, and Physiology.

The primary scientific topics Johansson investigates include Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Hormonal Regulation and Hypertension, Adipose Tissue and Metabolism, Analytical Chemistry and Chromatography, Receptor Mechanisms and Signaling, and Liver Disease Diagnosis and Treatment.

Johansson has published multiple articles in several scientific journals, with frequent contributions to Clinical Pharmacology & Therapeutics, which published five of their papers. Other publication venues include Scientific Reports with two papers, and single publications in Cells, Science Translational Medicine, and bioRxiv (Cold Spring Harbor Laboratory).

Recent papers by Johansson highlight diverse aspects of pharmacology and liver research:

  • Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis, 2020, Cells
  • Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data, 2021, Science Translational Medicine
  • Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes, 2020, Clinical Pharmacology & Therapeutics
  • The Polymorphic Nuclear Factor NFIB Regulates Hepatic CYP2D6 Expression and Influences Risperidone Metabolism in Psychiatric Patients, 2022, Clinical Pharmacology & Therapeutics
  • Androgen Receptors in Epithelial Cells Regulate Thymopoiesis and Recent Thymic Emigrants in Male Mice, 2020, Frontiers in Immunology

Johansson's collaborative network includes frequent co-authorship with researchers such as Magnus Ingelman-Sundberg (11 publications), Åsa Tivesten (5 publications), Maaike van der Lee (3 publications), Henk-Jan Guchelaar (3 publications), and Jesse J. Swen (3 publications).

Best Publications

  • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

    Inger Johansson;Eva Lundqvist;Leif Bertilsson;Marja-Liisa Dahl

  • Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

    I. Johansson;M. Oscarson;Qun-Ying Yue;L. Bertilsson

  • Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies.

    Johansson I;Ekström G;Scholte B;Puzycki D

  • Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population

    Ümit Yasar;Erik Eliasson;Marja-Liisa Dahl;Inger Johansson

  • Ethanol-Inducible Cytochrome P4502E1: Genetic Polymorphism, Regulation, and Possible Role in the Etiology of Alcohol-Induced Liver Disease

    Magnus Ingelman-Sundberg;Inger Johansson;Hu Yin;Ylva Terelius

  • Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.

    Anna Westlind-Johnsson;Sarah Malmebo;Anna Johansson;Charlotta Otter

  • Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine.

    L Bertilsson;M-L Dahl;F Sjöqvist;A Åberg-Wistedt

  • Genetic polymorphism and toxicology--with emphasis on cytochrome p450.

    Inger Johansson;Magnus Ingelman-Sundberg

  • The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine

    Birgit Eiermann;Georg Engel;Inger Johansson;Ulrich M. Zanger

  • Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450

    Inger Johansson;Magnus Ingelman-Sundberg

  • Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population.

    Marja‐Liisa Dahl;Inger Johansson;Margareta Porsmyr Palmertz;Magnus Ingelman‐Sundberg

  • Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43.

    Anna Westlind;Sarah Malmebo;Inger Johansson;Charlotta Otter

  • Genetic polymorphism of cytochrome P4502E1 in a Swedish population : relationship to incidence of lung cancer

    Irene Persson;Inger Johansson;Helene Bergung;Marja-Liisa Dahl

  • Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone.

    Maria Gabriella Scordo;Edoardo Spina;Gabriella Facciolà;Angela Avenoso

  • Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures

    Erik Eliasson;Inger Johansson;Magnus Ingelman-Sundberg

  • Centrilobular expression of ethanol-inducible cytochrome P-450 (IIE1) in rat liver.

    Magnus Ingelman-Sundberg;Inger Johansson;Kai E. Penttilä;Hans Glaumann

  • GENETIC MECHANISMS FOR DUPLICATION AND MULTIDUPLICATION OF THE HUMAN CYP2D6 GENE AND METHODS FOR DETECTION OF DUPLICATED CYP2D6 GENES

    Eva Lundqvist;Inger Johansson;Magnus Ingelman-Sundberg

  • A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function.

    Mikael Oscarson;Mats Hidestrand;Inger Johansson;Magnus Ingelman-Sundberg

  • Genetic polymorphism of human CYP2E1: characterization of two variant alleles.

    Yin Hu;Mikael Oscarson;Inger Johansson;Qun-Ying Yue

  • Benzene metabolism by ethanol-, acetone-, and benzene-inducible cytochrome P-450 (IIE1) in rat and rabbit liver microsomes.

    Inger Johansson;Magnus Ingelman-Sundberg

Frequent Co-Authors

Magnus Ingelman-Sundberg
Magnus Ingelman-Sundberg Karolinska Institute
Marja-Liisa Dahl
Marja-Liisa Dahl Karolinska University Hospital
Leif Bertilsson
Leif Bertilsson Karolinska University Hospital
Tommy B. Andersson
Tommy B. Andersson AstraZeneca (United Kingdom)
Folke Sjöqvist
Folke Sjöqvist Karolinska Institute
Cristina Rodríguez-Antona
Cristina Rodríguez-Antona Alberto Sols Biomedical Research Institute
Elmar Heinzle
Elmar Heinzle Saarland University
Volker M. Lauschke
Volker M. Lauschke Karolinska Institute
Ian A. Cotgreave
Ian A. Cotgreave Karolinska Institute
Ron H.N. van Schaik
Ron H.N. van Schaik Erasmus University Rotterdam

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