World's Best Scientists 2026 revealed!

Overview

J Van Snick is affiliated with Université Catholique de Louvain in Belgium. Their research spans across immunology, microbiology, and medicine with a notable focus on molecular biology and pulmonary and respiratory medicine. The scientist's work primarily investigates immune cell functions, signaling pathways such as TGF-β, and immune responses, integrating these themes in various disease contexts.

They have contributed to several fields including immunology, molecular biology, public health, environmental and occupational health, and biochemistry. The subfields emphasized in their research include:

  • Immunology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Immunology and Allergy
  • Public Health, Environmental and Occupational Health

Main topics explored in J Van Snick's publications cover key elements such as:

  • Immune Cell Function and Interaction
  • IL-33, ST2, and ILC Pathways
  • T-cell and B-cell Immunology
  • TGF-β signaling in diseases
  • Immunotherapy and Immune Responses
  • Cell Adhesion Molecules Research
  • Inflammasome and immune disorders

Their recent papers demonstrate a range of themes and publication venues. Noteworthy publications include:

  • Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma (2023) published in Signal Transduction and Targeted Therapy
  • Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation (2020) published in Frontiers in Immunology
  • NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells (2020) published in The Journal of Experimental Medicine
  • TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism (2021) published in Journal for ImmunoTherapy of Cancer
  • A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection (2020) published in Frontiers in Immunology

Frequent co-authors in their research include:

  • Catherine Uyttenhove
  • Jean-Paul Coutelier
  • Mohamed F. Mandour
  • Pyone Pyone Soe
  • Harry Sokol

J Van Snick's work has appeared predominantly in journals such as Frontiers in Immunology and International Journal of Molecular Sciences, as well as specialized venues like Signal Transduction and Targeted Therapy, The Journal of Experimental Medicine, and Journal for ImmunoTherapy of Cancer.

Best Publications

  • Interleukin-6: An Overview

    J L Van Snick

  • Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

    J Van Snick;S Cayphas;A Vink;C Uyttenhove

  • Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity

    C Uyttenhove;R J Simpson;J Van Snick

  • T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor.

    C Uyttenhove;P G Coulie;J Van Snick

  • Interleukin‐9 potentiates the interleukin‐4‐induced immunoglobulin (IgG, IgM and IgE) production by normal human B lymphocytes

    B Dugas;J C Renauld;J Pène;J Y Bonnefoy

  • Expression cloning of the murine and human interleukin 9 receptor cDNAs.

    J C Renauld;C Druez;A Kermouni;F Houssiau

  • Blockade of Interleukin-12 Function by Protein Vaccination Attenuates Atherosclerosis

    A.D. Hauer;C. Uyttenhove;P. de Vos;V. Stroobant

  • Cloning and Characterization of a Cdna for a New Mouse T-cell Growth-factor (p40)

    J Van Snick;A Goethals;J C Renauld;E Van Roost

  • A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9.

    J B Demoulin;C Uyttenhove;E Van Roost;B DeLestré

  • Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. II. T lymphocyte-mediated cytolysis.

    T Boon;J Van Snick;A Van Pel;C Uyttenhove

  • Interleukin-HP1, a T cell-derived hybridoma growth factor that supports the in vitro growth of murine plasmacytomas.

    J Van Snick;A Vink;S Cayphas;C Uyttenhove

  • Modulation of intestinal muscle contraction by interleukin-9 (IL-9) or IL-9 neutralization: correlation with worm expulsion in murine nematode infections.

    W. I. Khan;M. Richard;H. Akiho;P. A. Blennerhasset

  • The binding of human lactoferrin to mouse peritoneal cells.

    J L Van Snick;P L Masson

  • Interleukin-9 Enhances Resistance to the Intestinal Nematode Trichuris muris

    Helen Faulkner;J.-C. Renauld;J. Van Snick;R. K. Grencis

  • Separation and comparison of two monokines with lymphocyte-activating factor activity: IL-1 beta and hybridoma growth factor (HGF). Identification of leukocyte-derived HGF as IL-6

    J Van Damme;J Van Beeumen;B Decock;J Van Snick

  • Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells.

    M J Shlomchik;D A Nemazee;V L Sato;J Van Snick

  • Mouse plasmacytoma growth in vivo: enhancement by interleukin 6 (IL-6) and inhibition by antibodies directed against IL-6 or its receptor.

    A Vink;P Coulie;G Warnier;J C Renauld

  • Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene.

    J C Renauld;A Goethals;F Houssiau;H Merz

  • Rheumatoid factor (RF) production during anamnestic immune responses in the mouse. III. Activation of RF precursor cells is induced by their interaction with immune complexes and carrier-specific helper T cells.

    P G Coulie;J Van Snick

  • TCGF III/P40 is produced by naive murine CD4+ T cells but is not a general T cell growth factor.

    E Schmitt;R Van Brandwijk;J Van Snick;B Siebold

Frequent Co-Authors

Jean-Pierre Vaerman
Jean-Pierre Vaerman Université Catholique de Louvain
David W. Dunne
David W. Dunne University of Cambridge
Waliul I. Khan
Waliul I. Khan McMaster University
Carmine Vacca
Carmine Vacca University of Perugia

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Best Scientists Citing J Van Snick