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D-Index & Metrics

Medicine

D-Index
79
Citations
33422
World Ranking
17369
National Ranking
8701

Research.com Recognitions

  • 2019 - Member of the National Academy of Medicine (NAM)

Overview

Ernst Lengyel is affiliated with the University of Chicago in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology, reproductive medicine, cancer research, oncology, and immunology.

The main topics of Lengyel's work include ovarian cancer diagnosis and treatment, endometrial and cervical cancer treatments, cancer-related molecular mechanisms research, advanced proteomics techniques and applications, PARP inhibition in cancer therapy, cancer, lipids, and metabolism, and molecular biology techniques and applications.

Recent papers authored by Ernst Lengyel include:

  • Deep Visual Proteomics defines single-cell identity and heterogeneity (2022), published in Nature Biotechnology
  • Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis (2021), published in Cell
  • Updates and New Options in Advanced Epithelial Ovarian Cancer Treatment (2020), published in Obstetrics and Gynecology
  • Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance (2020), published in Cancer Research
  • A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis (2020), published in The Journal of Pathology

Frequent co-authors collaborating with Lengyel include Agnes Julia Bilecz, Hilary A. Kenny, Ricardo R. Lastra, Lisa Schweizer, and Matthias Mann.

The scientist's work appears regularly in several publication venues, including Cancer Research, Gynecologic Oncology, bioRxiv (Cold Spring Harbor Laboratory), Nature, and Cancer Cell.

Ernst Lengyel was named a Member of the National Academy of Medicine in 2019.

Best Publications

  • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

    Sun Mi Park;Arti B. Gaur;Ernst Lengyel;Marcus E. Peter

  • Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

    Kristin M Nieman;Hilary A Kenny;Carla V Penicka;Andras Ladanyi

  • Ovarian Cancer Development and Metastasis

    Ernst Lengyel

  • Rethinking ovarian cancer: recommendations for improving outcomes

    Sebastian Vaughan;Jermaine I. Coward;Robert C. Bast;Andy Berchuck

  • Whole-genome characterization of chemoresistant ovarian cancer

    Ann-Marie Patch;Ann-Marie Patch;Elizabeth Christie;Dariush Etemadmoghadam;Dariush Etemadmoghadam;Dale W. Garsed

  • Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

    David D. Bowtell;David D. Bowtell;Steffen Böhm;Ahmed A. Ahmed;Paul Joseph Aspuria

  • Adipose tissue and adipocytes support tumorigenesis and metastasis.

    Kristin M. Nieman;Iris L. Romero;Bennett Van Houten;Ernst Lengyel

  • Let-7 expression defines two differentiation stages of cancer.

    Scott Shell;Sun Mi Park;Amir Reza Radjabi;Robert Schickel

  • Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b.

    A Schnelzer;D Prechtel;U Knaus;K Dehne

  • Increased Expression of Matrix Metalloproteinases (MMP)-2, MMP-9, and the Urokinase-Type Plasminogen Activator Is Associated with Progression from Benign to Advanced Ovarian Cancer

    Barbara Schmalfeldt;Dieter Prechtel;Kathrin Härting;Kerstin Späthe

  • CD95 promotes tumour growth

    Lina Chen;Lina Chen;Sun Mi Park;Alexei V. Tumanov;Annika Hau;Annika Hau

  • Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via α5-Integrin, which Is a Therapeutic Target

    Kenjiro Sawada;Anirban K. Mitra;A. Reza Radjabi;Vinay Bhaskar

  • Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis.

    Andras Ladanyi;Andras Ladanyi;Abir Mukherjee;Hilary A. Kenny;Alyssa Johnson

  • The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin

    Hilary A. Kenny;Swayamjot Kaur;Lisa M. Coussens;Ernst Lengyel

  • MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer

    Anirban K. Mitra;Marion Zillhardt;Youjia Hua;Payal Tiwari

  • Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

    Mark A. Eckert;Fabian Coscia;Fabian Coscia;Agnieszka Chryplewicz;Jae Won Chang

  • Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy.

    Loren K. Mell;Loren K. Mell;Joel D. Kochanski;Joel D. Kochanski;John C. Roeske;John C. Roeske;Josh J. Haslam;Josh J. Haslam

  • C‐Met overexpression in node‐positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu

    Ernst Lengyel;Dieter Prechtel;James H. Resau;Katja Gauger

  • Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

    Won Jae Lee;Song Yi Ko;Muhaned S. Mohamed;Hilary A. Kenny

  • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors

    Sun-Mi Park;Arti B. Gaur;Ernst Lengyel;Marcus E. Peter

Frequent Co-Authors

Marcus E. Peter
Marcus E. Peter Northwestern University
Mark A. Eckert
Mark A. Eckert Medical University of South Carolina
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Douglas D. Boyd
Douglas D. Boyd The University of Texas MD Anderson Cancer Center
David D.L. Bowtell
David D.L. Bowtell Peter MacCallum Cancer Centre
Manfred Schmitt
Manfred Schmitt Technical University of Munich
Kenneth P. Nephew
Kenneth P. Nephew Indiana University
Oliver Fiehn
Oliver Fiehn University of California, Davis
Marc Ferrer
Marc Ferrer National Institutes of Health
Gini F. Fleming
Gini F. Fleming University of Chicago

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