World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
18814
World Ranking
4164
National Ranking
2038

Overview

Yogesh C. Awasthi is affiliated with the University of North Texas Health Science Center in the United States. Their research focuses primarily on biochemistry, genetics, molecular biology, and medicine, with a significant emphasis on oncology and molecular biology subfields. The scientist has contributed extensively to cancer research and related molecular pathways.

Their recent publications demonstrate engagement with a variety of topics including cancer-related molecular pathways, amino acid enzymes and metabolism, genomics, phytochemicals, oxidative stress, cancer lipids and metabolism, cellular transport and secretion, retinoids in leukemia and cellular processes, and peroxisome proliferator-activated receptors.

Recent papers authored by or involving Yogesh C. Awasthi include:

  • Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling (2020, Aging Cell)
  • SOX9: The master regulator of cell fate in breast cancer (2020, Biochemical Pharmacology)
  • Prognostic significance of natural products against multidrug tumor resistance (2023, Cancer Letters)
  • Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice (2020, Microorganisms)
  • Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway (2021, The Journal of Nutritional Biochemistry)

Yogesh C. Awasthi has frequently collaborated with several coauthors, including:

  • Sharad S. Singhal
  • Ravi Salgia
  • David Horne
  • Sharda P. Singh
  • Chhanda Bose

The scientist's work has appeared in multiple publication venues, with the most frequent being:

  • Cancers
  • Cancer Research
  • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • Cancer Letters
  • Carcinogenesis

Yogesh C. Awasthi's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of study covered by the scientist feature:

  • Molecular Biology
  • Oncology
  • Biochemistry
  • Cancer Research
  • Genetics

Their research covers significant topics such as:

  • Cancer-related Molecular Pathways
  • Amino Acid Enzymes and Metabolism
  • Genomics, Phytochemicals, and Oxidative Stress
  • Cancer, Lipids, and Metabolism
  • Cellular Transport and Secretion
  • Retinoids in Leukemia and Cellular Processes
  • Peroxisome Proliferator-Activated Receptors

Best Publications

  • NOMENCLATURE FOR HUMAN GLUTATHIONE TRANSFERASES

    B Mannervik;Y C Awasthi;P G Board;J D Hayes

  • Naturally occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties

    Piotr Zimniak;Bindu Nanduri;Sławomir Pikuła;Joanna Bandorowicz-Pikuła

  • Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation.

    Yusong Yang;Ji-Zhong Cheng;Sharad S. Singhal;Manjit Saini

  • Antioxidant Role of Glutathione S-Transferases: Protection Against Oxidant Toxicity and Regulation of Stress-Mediated Apoptosis

    Rajendra Sharma;Yusong Yang;Abha Sharma;Sanjay Awasthi

  • Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver

    John T Piper;Sharad S Singhal;Mohammad S Salameh;Robert T Torman

  • Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling.

    Yusong Yang;Rajendra Sharma;Abha Sharma;Sanjay Awasthi

  • Human glutathione S-transferases

    Yogesh C. Awasthi;Rashmi Sharma;Sharad S. Singhal

  • Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases.

    Yogesh C Awasthi;Yusong Yang;Narendra K Tiwari;Brad Patrick

  • Role of 4-hydroxynonenal in stress-mediated apoptosis signaling

    Yogesh C. Awasthi;Rajendra Sharma;J.Z. Cheng;Yusong Yang

  • Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress.

    Ji-Zhong Cheng;Rajendra Sharma;Yusong Yang;Sharad S. Singhal

  • Enzymatic conjugation of erythrocyte glutathione with 1-chloro-2,4- dinitrobenzene: the fate of glutathione conjugate in erythrocytes and the effect of glutathione depletion on hemoglobin

    Yogesh C. Awasthi;Hari S. Garg;Dat D. Dao;Catherine A. Partridge

  • Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons.

    Xun Hu;Hong Xia;Sanjay K. Srivastava;Christian Herzog

  • Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses.

    S Awasthi;S K Srivatava;J T Piper;S S Singhal

  • Mitogenic Responses of Vascular Smooth Muscle Cells to Lipid Peroxidation-derived Aldehyde 4-Hydroxy-trans-2-nonenal (HNE) ROLE OF ALDOSE REDUCTASE-CATALYZED REDUCTION OF THE HNE-GLUTATHIONE CONJUGATES IN REGULATING CELL GROWTH

    Kota V. Ramana;Aruni Bhatnagar;Sanjay Srivastava;Umesh C. S. Yadav

  • Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse.

    Mark R Engle;Sharda P Singh;Piotr J Czernik;Dana Gaddy

  • Transfection of mGSTA4 in HL-60 cells protects against 4-hydroxynonenal-induced apoptosis by inhibiting JNK-mediated signaling.

    Ji-Zhong Cheng;Sharad S. Singhal;Abha Sharma;Manjit Saini

  • Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistance.

    Sanjay Awasthi;Sharad S. Singhal;Rajendra Sharma;Piotr Zimniak

  • Curcumin–glutathione interactions and the role of human glutathione S-transferase P1-1

    Sanjay Awasthi;Utpal Pandya;Sharad S. Singhal;James T. Lin

  • The Role of Human Glutathione S-Transferases hGSTA1-1 and hGSTA2-2 in Protection against Oxidative Stress

    Tiejun Zhao;Sharad S. Singhal;John T. Piper;Jizhong Cheng

  • Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases.

    Yogesh C. Awasthi;Ghulam Ansari;Sanjay Awasthi

Frequent Co-Authors

Sanjay Awasthi
Sanjay Awasthi Texas Tech University Health Sciences Center
Sharad S. Singhal
Sharad S. Singhal The University of Texas at Arlington
Piotr Zimniak
Piotr Zimniak University of Arkansas for Medical Sciences
Shivendra V. Singh
Shivendra V. Singh University of Pittsburgh
Satish K. Srivastava
Satish K. Srivastava The University of Texas Medical Branch at Galveston
Sanjay K. Srivastava
Sanjay K. Srivastava Texas Tech University Health Sciences Center
Hasan Mukhtar
Hasan Mukhtar University of Wisconsin–Madison
Xinhua Ji
Xinhua Ji National Institutes of Health
Ernest Beutler
Ernest Beutler Scripps Research Institute
Damir Janigro
Damir Janigro Case Western Reserve University

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