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Biology and Biochemistry

D-Index
58
Citations
22538
World Ranking
12907
National Ranking
228

Overview

Urban Deutsch is affiliated with the University of Bern in Switzerland and has contributed extensively to research in the fields of Medicine and Neuroscience. Their work prominently spans subfields including Neurology, Immunology, Molecular Biology, Oncology, and Immunology and Allergy.

The scientist's research mainly focuses on several key topics: Barrier Structure and Function Studies, Neuroinflammation and Neurodegeneration Mechanisms, Drug Transport and Resistance Mechanisms, Cell Adhesion Molecules Research, Liver Disease Diagnosis and Treatment, Immunotherapy and Immune Responses, and Immune cells in cancer.

Urban Deutsch has published multiple papers in prominent journals. Some recent examples include:

  • Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis, 2020, Frontiers in Immunology
  • Nano-scale architecture of blood-brain barrier tight-junctions, 2021, eLife
  • Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood-brain barrier, 2021, Journal of Cell Science
  • VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation, 2023, Nature Communications
  • CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin, 2020, Cell Host & Microbe

The scientist's research has appeared frequently in specific venues, including:

  • Nature Communications
  • European Journal of Immunology
  • British journal of surgery
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)

Urban Deutsch regularly collaborates with several coauthors. Frequent collaborators include Britta Engelhardt, Benoît Zuber, Javier Pareja, Daniel Sánchez-Taltavull, and Adrian Keogh.

Best Publications

  • Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

    Thomas N. Sato;Yuzuru Tozawa;Urban Deutsch;Karen Wolburg-Buchholz

  • Structural and functional diversity of connexin genes in the mouse and human genome

    Klaus Willecke;Jürgen Eiberger;Joachim Degen;Dominik Eckardt

  • Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

    Ralf H. Adams;George A. Wilkinson;Cornelia Weiss;Francesca Diella

  • Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

    Yingdi Wang;Masanori Nakayama;Mara E. Pitulescu;Tim S. Schmidt

  • Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

    M. D. Goulding;G. Chalepakis;U. Deutsch;J. R. Erselius

  • Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.

    Thorsten M. Schlaeger;Sona Bartunkova;Joel A. Lawitts;Gunnar Teichmann

  • Pericytes and the Pathogenesis of Diabetic Retinopathy

    Hans Peter Hammes;Jihong Lin;Oliver Renner;Moshe Shani

  • Angiopoietin-1 induces sprouting angiogenesis in vitro

    Thomas I. Koblizek;Cornelia Weiss;George D. Yancopoulos;Urban Deutsch

  • Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system.

    Gregory R. Dressler;Urban Deutsch;Kamal Chowdhury;Howard O. Nornes

  • Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts.

    Pipsa Saharinen;Lauri Eklund;Lauri Eklund;Juho Miettinen;Riikka Wirkkala

  • The Mouse Gene for Vascular Endothelial Growth Factor GENOMIC STRUCTURE, DEFINITION OF THE TRANSCRIPTIONAL UNIT, AND CHARACTERIZATION OF TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL REGULATORY SEQUENCES

    David T. Shima;Masatoshi Kuroki;Urban Deutsch;Yin-Shan Ng;Yin-Shan Ng

  • Pax: A murine multigene family of paired box-containing genes

    Claudia Walther;Jean-Louis Guenet;Dominique Simon;Urban Deutsch

  • Spatially and temporally restricted expression of Pax2 during murine neurogenesis

    Howard O. Nornes;Gregory R. Dressler;Elzbieta W. Knapik;Urban Deutsch

  • VE‐PTP and VE‐cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

    Roman Nawroth;Gregor Poell;Alexander Ranft;Stephan Kloep

  • Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability

    David T. Shima;Urban Deutsch;Patricia A. D'Amore;Patricia A. D'Amore

  • EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase.

    Amparo Palmer;Manuel Zimmer;Kai S Erdmann;Volker Eulenburg

  • Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy.

    Hans Peter Hammes;Jihong Lin;Patrick Wagner;Yuxi Feng

  • undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1.

    Rudi Balling;Urban Deutsch;Peter Gruss

  • Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development

    Urban Deutsch;Gregory R. Dressler;Peter Gruss

  • The Cytoplasmic Domain of the Ligand EphrinB2 Is Required for Vascular Morphogenesis but Not Cranial Neural Crest Migration

    Ralf H. Adams;Francesca Diella;Silvia Hennig;Françoise Helmbacher

Frequent Co-Authors

Britta Engelhardt
Britta Engelhardt University of Bern
Dietmar Vestweber
Dietmar Vestweber Max Planck Society
Werner Risau
Werner Risau Max Planck Society
Hartwig Wolburg
Hartwig Wolburg University of Tübingen
Peter Gruss
Peter Gruss Okinawa Institute of Science and Technology
Ralf H. Adams
Ralf H. Adams Max Planck Society
Christer Betsholtz
Christer Betsholtz Uppsala University
Gregory R. Dressler
Gregory R. Dressler University of Michigan–Ann Arbor
Rudi Balling
Rudi Balling University of Bonn

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