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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
13945
World Ranking
9227
National Ranking
4084

Overview

Binfeng Lu is affiliated with the University of Pittsburgh in the United States. Their research spans multiple fields primarily focused on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Subfields of note include immunology, oncology, molecular biology, cancer research, and mechanical engineering.

The scientist's research topics emphasize various aspects of cancer immunotherapy, immune cell function, and gene delivery methods. Key topics include:

  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Single-cell and spatial transcriptomics
  • RNA Interference and Gene Delivery
  • IL-33, ST2, and ILC Pathways

Several recent papers exemplify the scope and focus of their work, including:

  • Targeting Xkr8 via nanoparticle-mediated in situ co-delivery of siRNA and chemotherapy drugs for cancer immunochemotherapy (2022), published in Nature Nanotechnology
  • Immune suppressed tumor microenvironment by exosomes derived from gastric cancer cells via modulating immune functions (2020), published in Scientific Reports
  • Improving cancer immunotherapy by rationally combining oncolytic virus with modulators targeting key signaling pathways (2022), published in Molecular Cancer
  • The IL-1 family in tumorigenesis and antitumor immunity (2022), published in Seminars in Cancer Biology
  • Tumor-Derived IL33 Promotes Tissue-Resident CD8+ T Cells and Is Required for Checkpoint Blockade Tumor Immunotherapy (2020), published in Cancer Immunology Research

Frequent co-authors collaborating with Binfeng Lu include:

  • Runzi Sun
  • Song Li
  • Jingting Jiang
  • Xinghua Lu
  • Lujia Chen

Their publications appear often in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • Frontiers in Cell and Developmental Biology
  • Journal for ImmunoTherapy of Cancer
  • Cancer Immunology Research

Best Publications

  • Neuronal Activity–Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

    Dengke K. Ma;Mi Hyeon Jang;Junjie U. Guo;Yasuji Kitabatake

  • Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

    Wen–Xing Ding;Min Li;Xiaoyun Chen;Hong–Min Ni;Hong–Min Ni

  • Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β1–induced Pulmonary Fibrosis

    Chun Geun Lee;Soo Jung Cho;Min Jong Kang;Svetlana P. Chapoval

  • TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression.

    Xin Gao;Yibei Zhu;Yibei Zhu;Gang Li;Haitao Huang

  • CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

    Moa Fransson;Elena Piras;Joachim Burman;Berith Nilsson

  • Autophagy Is Induced in CD4+ T Cells and Important for the Growth Factor-Withdrawal Cell Death

    Changyou Li;Elizabeth Capan;Yani Zhao;Jianping Zhao

  • Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics

    Zong Sheng Guo;Binfeng Lu;Zongbi Guo;Esther Giehl

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • PD-1 Blockade Boosts Radiofrequency Ablation–Elicited Adaptive Immune Responses against Tumor

    Liangrong Shi;Lujun Chen;Changping Wu;Yibei Zhu

  • Tumoral Expression of IL-33 Inhibits Tumor Growth and Modifies the Tumor Microenvironment through CD8+ T and NK Cells

    Xin Gao;Xuefeng Wang;Qianting Yang;Xin Zhao

  • TIM-3 as a Target for Cancer Immunotherapy and Mechanisms of Action

    Wenwen Du;Min Yang;Abbey Turner;Chunling Xu

  • Immune Modulation by Volatile Anesthetics

    Lindsay M. Stollings;Li-Jie Jia;Pei Tang;Huanyu Dou

  • Soluble CD276 (B7-H3) is released from monocytes, dendritic cells and activated T cells and is detectable in normal human serum.

    Guangbo Zhang;Jianquan Hou;Jinfang Shi;Gehua Yu

  • Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery

    J R Kovacs;C Li;Q Yang;G Li;G Li

  • IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8+ T cells

    Qianting Yang;Gang Li;Gang Li;Yibei Zhu;Yibei Zhu;Lin Liu

  • An Increased Abundance of Tumor-Infiltrating Regulatory T Cells Is Correlated with the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma

    Yichen Tang;Xuejun Xu;Shixiang Guo;Chaobin Zhang

  • GADD45γ Mediates the Activation of the p38 and JNK MAP Kinase Pathways and Cytokine Production in Effector TH1 Cells

    Binfeng Lu;Hong Yu;Chi Wing Chow;Baiyong Li

  • Cytokine-induced killer cells promote antitumor immunity.

    Jingting Jiang;Changping Wu;Binfeng Lu

  • T-bet and Eomesodermin Are Required for T Cell-Mediated Antitumor Immune Responses

    Yibei Zhu;Songguang Ju;Elizabeth Chen;Shao Dai

  • Too Much of a Good Thing? Tim-3 and TCR Signaling in T Cell Exhaustion

    Robert L. Ferris;Binfeng Lu;Lawrence P. Kane

Frequent Co-Authors

Jingting Jiang
Jingting Jiang Soochow University
Xueguang Zhang
Xueguang Zhang Soochow University
Richard A. Flavell
Richard A. Flavell Yale University
Song Li
Song Li University of Pittsburgh
Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Sergio Lavandero
Sergio Lavandero University of Chile
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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