Clifford A. Lingwood mainly investigates Biochemistry, Glycolipid, Receptor, Microbiology and Molecular biology. His work in Binding selectivity, Binding site, Glycolipid binding, Glycosphingolipid and Ceramide are all subfields of Biochemistry research. His research links In vitro with Glycolipid.
His Receptor research is multidisciplinary, incorporating elements of Bacterial adhesin, Globotriaosylceramide and Pathogenesis, Pathology. His study in Microbiology is interdisciplinary in nature, drawing from both Pokeweed mitogen and Escherichia coli. His Molecular biology research incorporates elements of Protein subunit, Endoplasmic reticulum, Endocytosis and Recombinant DNA.
Biochemistry, Receptor, Molecular biology, Glycolipid and Microbiology are his primary areas of study. His Biochemistry study frequently links to related topics such as Function. His research in Receptor tackles topics such as Pathology which are related to areas like Cytotoxic T cell.
His Molecular biology study incorporates themes from Recombinant DNA, Globotriaosylceramide, Endoplasmic reticulum, Cytotoxicity and Cell fusion. In his research on the topic of Glycolipid, Pathogenesis is strongly related with In vitro. His Microbiology research also works with subjects such as
His main research concerns Cell biology, Receptor, Molecular biology, Globotriaosylceramide and Biochemistry. His work on Intracellular and Golgi apparatus as part of general Cell biology research is often related to Erk1 2 signaling and Cardiac glycoside, thus linking different fields of science. He interconnects Ceramide and Pathology in the investigation of issues within Receptor.
His studies deal with areas such as ATPase, Chaperone, Virus, Endoplasmic reticulum and Mutant protein as well as Molecular biology. His Globotriaosylceramide research includes elements of Cell, Virology, Extracellular, Lipidomics and Flow cytometry. His research on Biochemistry often connects related areas such as Function.
Clifford A. Lingwood mostly deals with Receptor, Cell, Molecular biology, Shiga-like toxin and Glycolipid. Clifford A. Lingwood has included themes like Intracellular, Cell biology and Pathology in his Receptor study. In his work, Transferrin, Sphingomyelin, Cell membrane and Golgi apparatus is strongly intertwined with In vitro, which is a subfield of Cell.
The Molecular biology study combines topics in areas such as Virus, Viral replication, Chaperone and DNA replication. His Shiga-like toxin research is multidisciplinary, relying on both Apoptosis, Transcription Factor CHOP, Programmed cell death and DNA fragmentation. His study on Glycolipid is covered under Biochemistry.
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Acidic pH changes receptor binding specificity of Helicobacter pylori: a binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization.
M Huesca;S Borgia;P Hoffman;C A Lingwood.
Infection and Immunity (1996)
The glycerolipid receptor for Helicobacter pylori (and exoenzyme S) is phosphatidylethanolamine.
C A Lingwood;M Huesca;A Kuksis.
Infection and Immunity (1992)
Shiga toxin-associated hemolytic uremic syndrome: interleukin-1 beta enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro.
S A Kaye;C B Louise;B Boyd;C A Lingwood.
Infection and Immunity (1993)
Intracellular targeting of the endoplasmic reticulum/nuclear envelope by retrograde transport may determine cell hypersensitivity to verotoxin via globotriaosyl ceramide fatty acid isoform traffic.
Sara Arab;Clifford A. Lingwood.
Journal of Cellular Physiology (1998)
Differential tissue targeting and pathogenesis of verotoxins 1 and 2 in the mouse animal model
Niels W.P. Rutjes;Beth A. Binnington;Charles R. Smith;Mark D. Maloney.
Kidney International (2002)
Comparison of Helicobacter pylori and attaching-effacing Escherichia coli adhesion to eukaryotic cells.
M Dytoc;B Gold;M Louie;M Huesca.
Infection and Immunity (1993)
Retroviral Transfection of Madin-Darby Canine Kidney Cells with Human MDR1 Results in a Major Increase in Globotriaosylceramide and 105- to 106-Fold Increased Cell Sensitivity to Verocytotoxin ROLE OF P-GLYCOPROTEIN IN GLYCOLIPID SYNTHESIS
Prateek Lala;Shinya Ito;Clifford A. Lingwood.
Journal of Biological Chemistry (2000)
Globotriaosyl ceramide receptor function – Where membrane structure and pathology intersect
C.A. Lingwood;B. Binnington;A. Manis;D.R. Branch;D.R. Branch.
FEBS Letters (2010)
CD19 has a potential CD77 (globotriaosyl ceramide)-binding site with sequence similarity to verotoxin B-subunits: implications of molecular mimicry for B cell adhesion and enterohemorrhagic Escherichia coli pathogenesis.
Mark D. Maloney;Clifford A. Lingwood.
Journal of Experimental Medicine (1994)
Role of Multiple Drug Resistance Protein 1 in Neutral but Not Acidic Glycosphingolipid Biosynthesis
Maria Fabiana De Rosa;Daniel Sillence;Cameron Ackerley;Clifford A. Lingwood.
Journal of Biological Chemistry (2004)
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