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D-Index & Metrics

Molecular Biology

D-Index
65
Citations
16522
World Ranking
1664
National Ranking
841

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Gino A Cortopassi is affiliated with the University of California, Davis in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular focus on mitochondrial function and pathology.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of their work encompass:

  • Molecular Biology
  • Epidemiology
  • Environmental Chemistry
  • Organic Chemistry
  • Health, Toxicology and Mutagenesis

Core research topics addressed by Cortopassi consist of:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Environmental Chemistry and Analysis
  • Antimicrobial Agents and Applications
  • Water Treatment and Disinfection
  • Neuroscience and Neuropharmacology Research
  • Autophagy in Disease and Therapy

Notable recent publications authored or co-authored by Cortopassi include:

  • "Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern," 2023, Environmental Science & Technology
  • "Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter," 2021, Cell Reports
  • "Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism," 2023, Biochemical Pharmacology
  • "P46Shc Inhibits Mitochondrial ACAA2 Thiolase, Exacerbating Mitochondrial Injury and Inflammation in Aging Livers," 2024, American Journal Of Pathology

Frequent co-authors include:

  • Sandipan Datta
  • William A. Arnold
  • Arlene Blum
  • Jennifer Branyan
  • Thomas A. Bruton

The venues where Cortopassi has published most prominently are:

  • Environmental Science & Technology
  • Cell Reports
  • Biochemical Pharmacology
  • American Journal Of Pathology

In 2014, Gino A Cortopassi was awarded the distinction of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness.

    T R Prezant;J V Agapian;M C Bohlman;X Bu

  • Detection of a specific mitochondrial DNA deletion in tissues of older humans

    Gino A. Cortopassi;Norman Arnheim

  • A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.

    Gino A Cortopassi;D. Shibata;N. W. Soong;N. Arnheim

  • A simple method for site-directed mutagenesis using the polymerase chain reaction

    Anne Hemsley;Norman Arnheim;Michael Dennis Toney;Gino A Cortopassi

  • Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

    Anne N. Murphy;Dale E. Bredesen;Gino A Cortopassi;Endi Wang

  • Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

    Nay Wei Soong;David R. Hinton;Gino A Cortopassi;Norman Arnheim

  • A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.

    Megan N. Roberts;Marita A. Wallace;Alexey A. Tomilov;Zeyu Zhou

  • BCL2 translocation frequency rises with age in humans

    Yafei Liu;Antonio M. Hernandez;Darryl Shibata;Gino A. Cortopassi

  • The Friedreich's Ataxia Mutation Confers Cellular Sensitivity to Oxidant Stress Which Is Rescued by Chelators of Iron and Calcium and Inhibitors of Apoptosis

    Alice Wong;Joy Yang;Patrizia Cavadini;Cinzia Gellera

  • A molecular basis for human hypersensitivity to aminoglycoside antibiotics.

    Tim Hutchin;Ian Haworth;Koichiro Higashi;Nathan Fischel-Ghodsian

  • Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression

    Winyoo Chowanadisai;Kathryn A. Bauerly;Eskouhie Tchaparian;Alice Wong

  • Mitochondria in organismal aging and degeneration

    Gino A Cortopassi;Alice Wong

  • Induction of the Mitochondrial Permeability Transition Causes Release of the Apoptogenic Factor Cytochrome c

    Joy C Yang;Gino A Cortopassi

  • Deleterious mitochondrial DNA mutations accumulate in aging human tissues.

    Norman Arnheim;Gino A Cortopassi

  • A mitochondrial DNA clone is associated with increased risk for Alzheimer disease

    Timothy Hutchin;Gino A Cortopassi

  • OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability.

    Le Chen;Tingting Liu;Alice Tran;Xiyuan Lu

  • Genetic basis for susceptibility to noise-induced hearing loss in mice

    Rickie R. Davis;Rickie R. Davis;J. Kelly Newlander;Xiao Bing Ling;Gino A Cortopassi

  • Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells

    Alice Wong;Lucia Cavelier;Heather E. Collins-Schramm;Michael F Seldin

  • Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones

    Yuxi Shan;Eleonora Napoli;Gino A Cortopassi

  • Modelling the effects of age-related mtDNA mutation accumulation; Complex I deficiency, superoxide and cell death

    Gino A Cortopassi;Endi Wang

Frequent Co-Authors

Norman Arnheim
Norman Arnheim University of Southern California
Franco Taroni
Franco Taroni University of Milan
Valerio Carelli
Valerio Carelli University of Bologna
Pier Giuseppe Pelicci
Pier Giuseppe Pelicci European Institute of Oncology
Andrea Martinuzzi
Andrea Martinuzzi University of Turin
Bruce D. Hammock
Bruce D. Hammock University of California, Davis
Michael H.L. Green
Michael H.L. Green University of Brighton
Bo Lönnerdal
Bo Lönnerdal University of California, Davis
Sidney M. Hecht
Sidney M. Hecht Arizona State University
Anthony H.V. Schapira
Anthony H.V. Schapira University College London

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