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D-Index & Metrics

Chemistry

D-Index
51
Citations
8181
World Ranking
14101
National Ranking
786

Overview

Matthew P. Crump is affiliated with the University of Bristol in the United Kingdom. Their research spans various fields primarily within Biochemistry, Genetics and Molecular Biology, Medicine, and Chemistry. The scientist's work integrates significant contributions to subfields such as Molecular Biology, Pharmacology, Organic Chemistry, Cell Biology, and Biotechnology.

Crump's research focus includes the study of Microbial Natural Products and Biosynthesis, Carbohydrate Chemistry and Synthesis, and Synthetic Organic Chemistry Methods. Further topics addressed in their work encompass Genomics and Phylogenetic Studies, Cellular Transport and Secretion, Enzyme Catalysis and Immobilization, and Photosynthetic Processes and Mechanisms.

Frequent coauthors contributing to Crump's research include Christopher Williams, Christine L. Willis, Ashley J. Winter, Paul R. Race, and Luoyi Wang. Their collaboration suggests a network spanning various expertise aligned with Crump's research interests.

The scientist publishes regularly in multiple venues, with notable repeat appearances in Angewandte Chemie International Edition, Angewandte Chemie, Organic & Biomolecular Chemistry, Nature Communications, and Chemical Science.

Recent papers authored or coauthored by Matthew P. Crump include:

  • Polyketide β-branching: diversity, mechanism and selectivity, 2020, Natural Product Reports
  • The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI, 2020, Angewandte Chemie International Edition
  • Structural resolution of switchable states of a de novo peptide assembly, 2021, Nature Communications
  • Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans, 2022, Organic & Biomolecular Chemistry
  • An expandable, modular de novo protein platform for precision redox engineering, 2023, Proceedings of the National Academy of Sciences

Best Publications

  • Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

    Matthew P. Crump;Jiang Hong Gong;Pius Loetscher;Krishna Rajarathnam

  • A synthetic lectin analog for biomimetic disaccharide recognition.

    Yann Ferrand;Matthew P. Crump;Anthony P. Davis

  • A simple and accessible synthetic lectin for glucose recognition and sensing

    Chenfeng Ke;Harry Destecroix;Matthew P. Crump;Anthony P. Davis

  • A biomimetic receptor for glucose

    Robert A. Tromans;Tom S. Carter;Laurent Chabanne;Matthew P. Crump

  • The structural role of the carrier protein – active controller or passive carrier

    John Crosby;Matthew P. Crump

  • Carbohydrate Recognition in Water by a Tricyclic Polyamide Receptor

    Emmanuel Klein;Matthew P. Crump;Anthony P. Davis

  • Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2)

    Matthew P. Crump;John Crosby;Christopher E. Dempsey;John A. Parkinson

  • Authentic Heterologous Expression of the Tenellin Iterative Polyketide Synthase Nonribosomal Peptide Synthetase Requires Coexpression with an Enoyl Reductase

    Laura M. Halo;James W. Marshall;Ahmed A. Yakasai;Zhongshu Song

  • Structure of a pilin monomer from Pseudomonas aeruginosa: implications for the assembly of pili.

    D W Keizer;C M Slupsky;M Kalisiak;A P Campbell

  • Solution Structure of Eotaxin, a Chemokine That Selectively Recruits Eosinophils in Allergic Inflammation

    Matthew P. Crump;Krishna Rajarathnam;Key Sun Kim;Ian Clark-Lewis

  • Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.

    Pierre Lavigne;Matthew P. Crump;Stéphane M. Gagné;Robert S. Hodges

  • A Synthetic Lectin for O‐Linked β‐N‐Acetylglucosamine

    Yann Ferrand;Emmanuel Klein;Nicholas P. Barwell;Matthew P. Crump

  • A Synthetic Lectin for β‐Glucosyl

    Nicholas P. Barwell;Matthew P. Crump;Anthony P. Davis

  • A threading receptor for polysaccharides

    Tiddo J. Mooibroek;Juan M. Casas-Solvas;Robert L. Harniman;Charles M. Renney

  • Construction and in vivo assembly of a catalytically proficient and hyperthermostable de novo enzyme

    Daniel W. Watkins;Jonathan M. X. Jenkins;Katie J. Grayson;Nicola Wood

  • Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL.

    Sabine Kneissl;E. Joel Loveridge;Christopher Williams;Matthew P. Crump

  • Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer–nucleotide coacervate droplets

    John Crosby;Tom Treadwell;Michelle Hammerton;Konstantinos Vasilakis

  • Solution Structure and Dynamics of Oxytetracycline Polyketide Synthase Acyl Carrier Protein from Streptomyces rimosus

    Stuart C. Findlow;Claire Winsor;Thomas J. Simpson;John Crosby

  • The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

    Gemma Lm Fisher;César L. Pastrana;Victoria A. Higman;Alan Koh

  • Synthetic Receptors for the High-Affinity Recognition of O-GlcNAc Derivatives

    Pablo Rios;Tom S. Carter;Tiddo J. Mooibroek;Matthew P. Crump

Frequent Co-Authors

Thomas J. Simpson
Thomas J. Simpson University of Bristol
Christine L. Willis
Christine L. Willis University of Bristol
Russell J. Cox
Russell J. Cox University of Hannover
Brian D. Sykes
Brian D. Sykes University of Alberta
Anthony P. Davis
Anthony P. Davis University of Bristol
Richard B. Sessions
Richard B. Sessions University of Bristol
Christopher M. Thomas
Christopher M. Thomas University of Birmingham
Ian Clark-Lewis
Ian Clark-Lewis University of British Columbia
Derek N. Woolfson
Derek N. Woolfson University of Bristol
E Y Jones
E Y Jones University of Oxford

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