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Biology and Biochemistry

D-Index
75
Citations
35783
World Ranking
5194
National Ranking
2469

Overview

Andras Perl is affiliated with SUNY Upstate Medical University in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with a substantial body of work spanning these disciplines.

The primary subfields of study in their research include:

  • Immunology
  • Rheumatology
  • Molecular Biology
  • Pathology and Forensic Medicine
  • Genetics

Andras Perl's research covers a variety of main topics, notably:

  • Systemic Lupus Erythematosus Research
  • PI3K/AKT/mTOR signaling in cancer
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Neonatal Health and Biochemistry
  • Monoclonal and Polyclonal Antibodies Research
  • Innovations in Medical Education

The scientist's recent publications include:

  • Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine, 2020, Clinical Immunology
  • Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation, 2024, Nature Communications
  • Metabolic Targets for Treatment of Autoimmune Diseases, 2020, Immunometabolism
  • Renal mTORC1 activation is associated with disease activity and prognosis in lupus nephritis, 2022, Lara D. Veeken
  • Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis, 2023, Nature Metabolism

Frequent co-authors in Andras Perl's work include:

  • Akshay Patel
  • Katalin Bánki
  • Dániel Krakkó
  • Thomas Winans
  • Zachary Oaks

Publication venues where Andras Perl has frequently published are:

  • Clinical Immunology
  • ACR Open Rheumatology
  • Frontiers in Immunology
  • Autoimmunity Reviews
  • Nature Communications

In addition to articles, Andras Perl has authored a book published by Frontiers Media titled New Biomarkers for the Diagnosis and Treatment of Systemic Lupus Erythematosus (2022).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus.

    Peter Gergely;Craig Grossman;Brian Niland;Ferenc Puskas

  • N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: A randomized, double-blind, placebo-controlled trial

    Zhi-Wei Lai;Robert Hanczko;Eduardo Bonilla;Tiffany N. Caza

  • Rapamycin reduces disease activity and normalizes T cell activation–induced calcium fluxing in patients with systemic lupus erythematosus

    David Fernandez;Eduardo Bonilla;Naureen Mirza;Brian Niland

  • Oxidative stress in the pathology and treatment of systemic lupus erythematosus.

    Andras Perl

  • Elevation of Mitochondrial Transmembrane Potential and Reactive Oxygen Intermediate Levels Are Early Events and Occur Independently from Activation of Caspases in Fas Signaling

    Katalin Banki;Eliza Hutter;Nick J. Gonchoroff;Andras Perl

  • Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial

    Zhi-Wei Lai;Ryan Kelly;Thomas Winans;Ivan Marchena

  • Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases

    Andras Perl

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Glutathione Levels and Sensitivity to Apoptosis Are Regulated by Changes in Transaldolase Expression

    Katalin Banki;Eliza Hutter;Emanuela Colombo;Nick J. Gonchoroff

  • Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity.

    Andras Perl;Peter Gergely;Gyorgy Nagy;Agnes Koncz

  • Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.

    David R. Fernandez;Tiffany Telarico;Eduardo Bonilla;Qing Li

  • mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

    Andras Perl

  • Persistent Mitochondrial Hyperpolarization, Increased Reactive Oxygen Intermediate Production, and Cytoplasmic Alkalinization Characterize Altered IL-10 Signaling in Patients with Systemic Lupus Erythematosus

    Peter Gergely;Brian Niland;Nick Gonchoroff;Rudolf Pullmann

  • Human T-cell lymphotropic virus (HTLV)-related endogenous sequence, HRES-1, encodes a 28-kDa protein: a possible autoantigen for HTLV-I gag-reactive autoantibodies.

    K Banki;J Maceda;E Hurley;E Ablonczy

  • Endogenous retroviruses : potential etiologic agents in autoimmunity

    Arthur M. Krieg;Mark F. Gourley;Andras Perl

  • T Cell Activation-Induced Mitochondrial Hyperpolarization Is Mediated by Ca2+- and Redox-Dependent Production of Nitric Oxide

    Gyorgy Nagy;Agnes Koncz;Andras Perl

  • Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and sysemic lupus erythematosus

    György Nagy;Agnes Koncz;Tiffany Telarico;David Fernandez

Frequent Co-Authors

Sergio Lavandero
Sergio Lavandero University of Chile
Frank A. Middleton
Frank A. Middleton SUNY Upstate Medical University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Walter Malorni
Walter Malorni University of Rome Tor Vergata
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Elena Ortona
Elena Ortona Istituto Superiore di Sanità
Patrick A. Lewis
Patrick A. Lewis University College London

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