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Immunology

D-Index
56
Citations
12245
World Ranking
3708
National Ranking
1709

Overview

Bruce C. Richardson is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on immunology and microbiology, with a specific concentration in immunology and rheumatology subfields.

The scientist's recent publications highlight an emphasis on systemic lupus erythematosus (SLE) and immune cell function. Notable papers include:

  • Associations between CD70 methylation of T cell DNA and age in adults with systemic lupus erythematosus and population controls: The Michigan Lupus Epidemiology & Surveillance (MILES) Program, 2023, published in the Journal of Autoimmunity
  • EXPOSURE TO PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) AND SYSTEMIC LUPUS ERYTHEMATOSUS: A PILOT STUDY IN THE MICHIGAN LUPUS EPIDEMIOLOGY & SURVEILLANCE (MILES) PROGRAM, 2025, published in The Journal of Rheumatology

Bruce C. Richardson collaborates frequently with a number of researchers in their field. Their recurring coauthors include:

  • Emily C. Somers
  • Jaclyn M. Goodrich
  • Lu Wang
  • Sioḃán D. Harlow
  • Wendy Marder

Their work has appeared in specific peer-reviewed venues such as:

  • Journal of Autoimmunity
  • The Journal of Rheumatology

Their research topics primarily revolve around understanding immune cell function and interaction, T-cell and B-cell immunology, and systemic lupus erythematosus research. These topics reflect the integration of molecular, cellular, and environmental factors in autoimmune disease mechanisms.

Best Publications

  • The MAPK signalling pathways and colorectal cancer.

    Jing Yuan Fang;Bruce C Richardson

  • Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis.

    Bruce C. Richardson;Lee Scheinbart;John R. Strahler;Laura A. Gross

  • Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice.

    Jawaid Quddus;Kent J. Johnson;Jerrie Gavalchin;Edward P. Amento

  • Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus.

    Qianjin Lu;Mariana J. Kaplan;Donna Ray;Doreen Ray

  • Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity

    Sanjay Rajagopalan;Emily C. Somers;Robert D. Brook;Christine Kehrer

  • Demethylation of the Same Promoter Sequence Increases CD70 Expression in Lupus T Cells and T Cells Treated with Lupus-Inducing Drugs1

    Unknown

  • Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis

    Unknown

  • Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo.

    R. L. Yung;Jawaid Quddus;C. E. Chrisp;K. J. Johnson

  • Decreased ras–mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients

    Chun Deng;Mariana J. Kaplan;Jun Yang;Donna Ray

  • The Epigenetic Face of Systemic Lupus Erythematosus

    Esteban Ballestar;Manel Esteller;Bruce C. Richardson

  • Fas ligation triggers apoptosis in macrophages but not endothelial cells

    Bruce C. Richardson;Narendra D. Lalwani;Kent J. Johnson;Rory M. Marks

  • Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors

    Kurt Oelke;Qianjin Lu;Derek Richardson;Ailing Wu

  • Role of DNA methylation in the regulation of cell function: autoimmunity, aging and cancer.

    Bruce C. Richardson

  • Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus.

    Bruce C. Richardson;John R. Strahler;T. Scott Pivirotto;Jawaid Quddus

  • Drug-induced lupus.

    Raymond L. Yung;Bruce C. Richardson

  • The Apoptotic Ligands TRAIL, TWEAK, and Fas Ligand Mediate Monocyte Death Induced by Autologous Lupus T Cells

    Mariana J. Kaplan;Emily E. Lewis;Eric A. Shelden;Emily Somers

  • Abnormal T cell signal transduction in systemic lupus erythematosus

    Gary M. Kammer;Andras Perl;Bruce C. Richardson;George C. Tsokos

  • Effect of an inhibitor of DNA methylation on T cells. II. 5-azacytidine induces self-reactivity in antigen-specific T4+ cells

    Bruce C. Richardson

  • Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients

    Ryan Webb;Jennifer A Kelly;Emily C Somers;Travis Hughes

  • Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated mice.

    A A Vink;F M Strickland;C Bucana;P A Cox

  • TRAIL (Apo2 ligand) and TWEAK (Apo3 ligand) mediate CD4+ T cell killing of antigen-presenting macrophages.

    Mariana J. Kaplan;Donna Ray;Ru Ran Mo;Raymond L. Yung

  • Epigenetics in human autoimmunity: (Epigenetics in autoimmunity—DNA methylation in systemic lupus erythematosus and beyond)

    Faith M Strickland;Bruce C Richardson

  • Lymphocyte function—associated antigen 1 overexpression and t cell autoreactivity

    Bruce Richardson;Daniel Powers;Forrest Hooper;Raymond L. Yung

  • Mechanisms of drug‐induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo

    Raymond L. Yung;Sandra Chang;Nahid Hemati;Kent J. Johnson

Frequent Co-Authors

Raymond Yung
Raymond Yung University of Michigan–Ann Arbor
Kent J. Johnson
Kent J. Johnson University of Michigan–Ann Arbor
Amr H. Sawalha
Amr H. Sawalha University of Pittsburgh
Samir M. Hanash
Samir M. Hanash The University of Texas MD Anderson Cancer Center
Mariana J. Kaplan
Mariana J. Kaplan National Institutes of Health
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
John B. Harley
John B. Harley United States Department of Veterans Affairs
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation

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