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Frank A. Middleton

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
29347
World Ranking
9961
National Ranking
4362

Frank A. Middleton publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Frank A. Middleton sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 185 publications — 43rd percentile

43% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Frank A. Middleton D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Frank A. Middleton sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Frank A. Middleton is affiliated with SUNY Upstate Medical University in the United States. Their research spans multiple fields with a primary focus on Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Middleton's work engages deeply with subfields such as Infectious Diseases, Molecular Biology, Neurology, Biological Psychiatry, and Epidemiology.

The main topics covered in their research include:

  • Tryptophan and brain disorders
  • SARS-CoV-2 detection and testing
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Mitochondrial Function and Pathology
  • Stress Responses and Cortisol
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies

Middleton has contributed to various recent papers addressing diverse biomedical and public health issues. Some key publications include:

  • Co-quantification of crAssphage increases confidence in wastewater-based epidemiology for SARS-CoV-2 in low prevalence areas (2021), published in Water Research X
  • Quantification of SARS-CoV-2 and cross-assembly phage (crAssphage) from wastewater to monitor coronavirus transmission within communities (2020), in bioRxiv (Cold Spring Harbor Laboratory)
  • Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation (2024), Nature Communications
  • Diagnosing mild traumatic brain injury using saliva RNA compared to cognitive and balance testing (2020), Clinical and Translational Medicine
  • Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis (2023), Nature Metabolism

Their frequent co-authors include:

  • Maree J. Webster
  • Cynthia Shannon Weickert
  • Yunting Zhu
  • Paul T. Massa
  • David A. Larsen

Middleton regularly publishes in notable venues, with the most frequent being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain Behavior and Immunity
  • Nature Metabolism
  • The International Journal of Neuropsychopharmacology
  • Water Research X

Best Publications

  • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

    Shaun M. Purcell;Shaun M. Purcell;Naomi R. Wray;Jennifer L. Stone;Jennifer L. Stone;Peter M. Visscher

  • Basal ganglia and cerebellar loops: motor and cognitive circuits.

    Frank A Middleton;Peter L Strick;Peter L Strick

  • Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function

    Frank A. Middleton;Peter L. Strick

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Cerebellar Projections to the Prefrontal Cortex of the Primate

    Frank A. Middleton;Peter L. Strick;Peter L. Strick

  • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex.

    Károly Mirnics;Frank A. Middleton;Adriana Marquez;David A. Lewis

  • PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

    Bin Zheng;Zhixiang Liao;Joseph J. Locascio;Kristen A. Lesniak

  • Basal Ganglia Output and Cognition: Evidence from Anatomical, Behavioral, and Clinical Studies

    Frank A. Middleton;Peter L. Strick

  • Environmental risk factors for attention-deficit hyperactivity disorder

    Tania Das Banerjee;Frank Middleton;Stephen V. Faraone

  • Meta-Analysis of Genome-Wide Association Studies of Attention- Deficit/Hyperactivity Disorder

    Benjamin M. Neale;Benjamin M. Neale;Sarah E. Medland;Sarah E. Medland;Stephan Ripke;Stephan Ripke;Philip Asherson

  • Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia.

    K. Mirnics;F. A. Middleton;G. D. Stanwood;D. A. Lewis

  • Basal-ganglia ‘Projections’ to the Prefrontal Cortex of the Primate

    Frank A. Middleton;Peter L. Strick

  • Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

    Károly Mirnics;Frank A. Middleton;David A. Lewis;Pat Levitt

  • Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

    Frank A. Middleton;Karoly Mirnics;Joseph N. Pierri;David A. Lewis

  • Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication.

    J Fuchs;Christer Nilsson;J Kachergus;M Munz

  • Association and linkage analyses of RGS4 polymorphisms in schizophrenia

    Kodavali V. Chowdari;Karoly Mirnics;Prachi Semwal;Joel Wood

  • Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

    Josephine Elia;Joseph T. Glessner;Kai Wang;Nagahide Takahashi

  • The temporal lobe is a target of output from the basal ganglia

    Frank A. Middleton;Peter L. Strick

  • Genomic investigation of alpha-synuclein multiplication and parkinsonism

    Owen A. Ross;Adam T. Braithwaite;Lisa M. Skipper;Jennifer Kachergus

  • Cerebellar output channels.

    Frank A. Middleton;Peter L. Strick

Frequent Co-Authors

Hans-Christoph Steinhausen
Hans-Christoph Steinhausen University of Southern Denmark
Benjamin M. Neale
Benjamin M. Neale Harvard University
Peter L. Strick
Peter L. Strick University of Pittsburgh
Pat Levitt
Pat Levitt University of Southern California
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Kevin M. Antshel
Kevin M. Antshel Syracuse University
Susanne Walitza
Susanne Walitza University of Zurich
Wendy R. Kates
Wendy R. Kates SUNY Upstate Medical University
Eric Mick
Eric Mick University of Massachusetts Chan Medical School
David A. Lewis
David A. Lewis University of Pittsburgh

External Links

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Best Scientists Citing Frank A. Middleton

David A. Lewis

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University of Pittsburgh

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Jeremy D. Schmahmann

Jeremy D. Schmahmann

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Publications: 61

Michael Conlon O'Donovan

Michael Conlon O'Donovan

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Publications: 59

Andras Perl

Andras Perl

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Publications: 58

Karoly Mirnics

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Publications: 57

Barbara Franke

Barbara Franke

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Publications: 53

Klaus-Peter Lesch

Klaus-Peter Lesch

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Publications: 53

Hakon Hakonarson

Hakon Hakonarson

Children's Hospital of Philadelphia

Publications: 52

Benjamin M. Neale

Benjamin M. Neale

Harvard University

Publications: 43

Michael John Owen

Michael John Owen

Cardiff University

Publications: 42

Jan Haavik

Jan Haavik

University of Bergen

Publications: 40

Jan K. Buitelaar

Jan K. Buitelaar

Radboud University

Publications: 38

Pat Levitt

Pat Levitt

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Publications: 37

Philip Asherson

Philip Asherson

King's College London

Publications: 36

Vishwajit L. Nimgaonkar

Vishwajit L. Nimgaonkar

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Publications: 35

Andreas Reif

Andreas Reif

Goethe University Frankfurt

Publications: 35

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