His main research concerns Genetics, Chromatin, Molecular biology, Cell biology and Histone. His Chromatin study combines topics in areas such as Promoter, Chromatin immunoprecipitation and Enhancer, Transcription factor, Transcriptional regulation. Ernesto Guccione works mostly in the field of Molecular biology, limiting it down to topics relating to Exon and, in certain cases, Tumor suppressor gene, as a part of the same area of interest.
His research in Cell biology intersects with topics in Virus and Human papillomavirus. In the subject of general Histone, his work in PRC2, WDR5 and Histone H3 is often linked to Euchromatin, thereby combining diverse domains of study. His biological study spans a wide range of topics, including Gene expression and RNA splicing.
Cell biology, Cancer research, Chromatin, Genetics and Epigenetics are his primary areas of study. His Cell biology research incorporates themes from Gene knockdown, Carcinogenesis, Protein arginine methyltransferase 5, Methyltransferase and Histone. His Cancer research research includes themes of Cancer cell, Cancer, RNA splicing and EHMT2.
His RNA splicing study also includes fields such as
His scientific interests lie mostly in Cell biology, Cancer research, Epigenetics, Methyltransferase and Methylation. His research integrates issues of Cell growth, Histone, Gene, Gene knockdown and PRDM9 in his study of Cell biology. His Gene study deals with the bigger picture of Genetics.
Ernesto Guccione interconnects EZH2, Wnt signaling pathway, Gene silencing and EHMT2 in the investigation of issues within Cancer research. His Epigenetics research includes elements of Chromatin, Regulation of gene expression and Protein kinase B. His Methylation research is multidisciplinary, relying on both RNA Splicing Factors, Arginine, Myeloid leukemia and Mutant.
His primary areas of study are Methyltransferase, Cancer research, Methylation, Cell biology and RNA. His primary area of study in Methyltransferase is in the field of Protein arginine methyltransferase 5. The Cancer research study combines topics in areas such as Cancer, Immunotherapy, Gene silencing and EZH2.
His EZH2 research is multidisciplinary, incorporating elements of Cell culture and Histone H3. He works mostly in the field of Methylation, limiting it down to concerns involving Arginine and, occasionally, Computational biology, Clinical significance, Transcription, Signal transduction and Rna processing. Ernesto Guccione combines subjects such as HEK 293 cells, Histone, Subfamily and PRDM9 with his study of Cell biology.
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The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism
Carlos Sebastián;Bernardette M. M. Zwaans;Dafne Magali Silberman;Dafne Magali Silberman;Melissa Gymrek.
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive
Ernesto Guccione;Christian Bassi;Fabio Casadio;Francesca Martinato.
Myc-binding-site recognition in the human genome is determined by chromatin context
Ernesto Guccione;Francesca Martinato;Giacomo Finocchiaro;Lucilla Luzi.
Nature Cell Biology (2006)
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
Arianna Sabò;Arianna Sabò;Theresia R. Kress;Theresia R. Kress;Mattia Pelizzola;Stefano de Pretis.
Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance
Valentina Migliori;Julius Müller;Sameer Phalke;Diana Low.
Nature Structural & Molecular Biology (2012)
Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation.
Miranda Thomas;Richard Laura;Karin Hepner;Ernesto Guccione.
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
Cheryl M. Koh;Marco Bezzi;Diana H P Low;Wei X ia Ang.
Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia.
Anna Migliazza;Anna Migliazza;Anna Migliazza;Francesc Bosch;Francesc Bosch;Francesc Bosch;Hirokazu Komatsu;Hirokazu Komatsu;Hirokazu Komatsu;Eftihia Cayanis;Eftihia Cayanis;Eftihia Cayanis.
Chromatin and Transcription Transitions of Mammalian Adult Germline Stem Cells and Spermatogenesis
Saher Sue Hammoud;Diana H.P. Low;Diana H.P. Low;Chongil Yi;Douglas T. Carrell.
Cell Stem Cell (2014)
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery
Marco Bezzi;Shun Xie Teo;Julius Muller;Wei Chuen Mok.
Genes & Development (2013)
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