What is he best known for?
The fields of study he is best known for:
- Gene
- Gene expression
- Enzyme
His main research concerns Genetics, Chromatin, Molecular biology, Cell biology and Histone.
His Chromatin study combines topics in areas such as Promoter, Chromatin immunoprecipitation and Enhancer, Transcription factor, Transcriptional regulation.
Ernesto Guccione works mostly in the field of Molecular biology, limiting it down to topics relating to Exon and, in certain cases, Tumor suppressor gene, as a part of the same area of interest.
His research in Cell biology intersects with topics in Virus and Human papillomavirus.
In the subject of general Histone, his work in PRC2, WDR5 and Histone H3 is often linked to Euchromatin, thereby combining diverse domains of study.
His biological study spans a wide range of topics, including Gene expression and RNA splicing.
His most cited work include:
- The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism (439 citations)
- Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive (352 citations)
- Myc-binding-site recognition in the human genome is determined by chromatin context (315 citations)
What are the main themes of his work throughout his whole career to date?
Cell biology, Cancer research, Chromatin, Genetics and Epigenetics are his primary areas of study.
His Cell biology research incorporates themes from Gene knockdown, Carcinogenesis, Protein arginine methyltransferase 5, Methyltransferase and Histone.
His Cancer research research includes themes of Cancer cell, Cancer, RNA splicing and EHMT2.
His RNA splicing study also includes fields such as
- Gene expression that intertwine with fields like RNA,
- Exon, which have a strong connection to Tumor suppressor gene.
The various areas that Ernesto Guccione examines in his Chromatin study include Cell Plasticity, Wnt signaling pathway, DNA methylation, Chromatin immunoprecipitation and Transcription factor.
His Gene, Kidney and Phenotype study in the realm of Genetics connects with subjects such as Disease gene identification.
He most often published in these fields:
- Cell biology (49.21%)
- Cancer research (38.10%)
- Chromatin (28.57%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (49.21%)
- Cancer research (38.10%)
- Epigenetics (26.98%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cell biology, Cancer research, Epigenetics, Methyltransferase and Methylation.
His research integrates issues of Cell growth, Histone, Gene, Gene knockdown and PRDM9 in his study of Cell biology.
His Gene study deals with the bigger picture of Genetics.
Ernesto Guccione interconnects EZH2, Wnt signaling pathway, Gene silencing and EHMT2 in the investigation of issues within Cancer research.
His Epigenetics research includes elements of Chromatin, Regulation of gene expression and Protein kinase B.
His Methylation research is multidisciplinary, relying on both RNA Splicing Factors, Arginine, Myeloid leukemia and Mutant.
Between 2018 and 2021, his most popular works were:
- The regulation, functions and clinical relevance of arginine methylation. (94 citations)
- Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. (49 citations)
- Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. (49 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Gene expression
His primary areas of study are Methyltransferase, Cancer research, Methylation, Cell biology and RNA.
His primary area of study in Methyltransferase is in the field of Protein arginine methyltransferase 5.
The Cancer research study combines topics in areas such as Cancer, Immunotherapy, Gene silencing and EZH2.
His EZH2 research is multidisciplinary, incorporating elements of Cell culture and Histone H3.
He works mostly in the field of Methylation, limiting it down to concerns involving Arginine and, occasionally, Computational biology, Clinical significance, Transcription, Signal transduction and Rna processing.
Ernesto Guccione combines subjects such as HEK 293 cells, Histone, Subfamily and PRDM9 with his study of Cell biology.
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