World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
72
Citations
20762
World Ranking
2203
National Ranking
85

Overview

Derek N.J. Hart was affiliated with the University of Sydney in Australia and contributed to research spanning multiple fields, including Medicine and Biochemistry, Genetics and Molecular Biology. Their work involved significant focus on Molecular Biology, Pathology and Forensic Medicine, Genetics, and Oncology as subfields.

The scientist's research topics covered a range of specialized areas, such as:

  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • CAR-T cell therapy research
  • DNA and Nucleic Acid Chemistry
  • RNA Interference and Gene Delivery
  • Lipid Membrane Structure and Behavior

Among recent publications, Hart authored and coauthored papers published in notable venues, including:

  • "Targeting CD83 in mantle cell lymphoma with anti-human CD83 antibody," published in 2020 in Clinical & Translational Immunology
  • "Kinetics of DNA Melting and Annealing Under Small Tension," published in 2021 in Biophysical Journal

These papers reflect research on immune-targeted therapies in lymphoma and biophysical studies of DNA behavior under mechanical tension. The publication venues-Clinical & Translational Immunology and Biophysical Journal-were frequent platforms for Hart's work.

Collaboration was part of Hart's research approach, working with coauthors such as:

  • Ziduo Li
  • Edward Abadir
  • Kenneth Lee
  • Candice Clarke
  • Christian Bryant

Their research contributions integrated both clinical and molecular perspectives, with an emphasis on understanding disease mechanisms and potential therapeutic interventions. Hart's studies in lymphoma and leukemia intersected with explorations of nucleic acid chemistry, suggesting a multidisciplinary approach within their scientific endeavors.

Best Publications

  • Nomenclature of monocytes and dendritic cells in blood.

    Loems Ziegler-Heitbrock;Petronela Ancuta;Suzanne Crowe;Marc Dalod;Marc Dalod

  • Dendritic cells: unique leukocyte populations which control the primary immune response.

    Derek N.J. Hart

  • Human CD141(+) (BDCA-3)(+) dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

    Sarah L. Jongbloed;Andrew J. Kassianos;Kylie J. McDonald;Georgina J. Clark

  • Type I IFNs Enhance the Terminal Differentiation of Dendritic Cells

    Thomas Luft;Ken C Pang;Elisabeth Thomas;Paul J Hertzog

  • Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-β1 and interleukin-10

    Ross D. Brown;Belinda Pope;Allan Murray;Warren Esdale

  • Dendritic cells: On the move from bench to bedside

    Frank O. Nestle;Jacques Banchereau;Derek Hart

  • Minimal Recruitment and Activation of Dendritic Cells Within Renal Cell Carcinoma

    A.J. Troy;K.L. Summers;P.J.T. Davidson;C.H. Atkinson

  • HIV gp120 receptors on human dendritic cells.

    Stuart G. Turville;Stuart G. Turville;Jim Arthos;Jim Arthos;Kelli Mac Donald;Kelli Mac Donald;Garry Lynch;Garry Lynch

  • Phenotypic characterization of five dendritic cell subsets in human tonsils

    Kelly L. Summers;Barry D. Hock;Judith L. McKenzie;Derek N.J. Hart

  • Isolation and characterization of human tonsil dendritic cells.

    D. N. J. Hart;J. L. Mckenzie

  • Monitoring Human Blood Dendritic Cell Numbers in Normal Individuals and in Stem Cell Transplantation

    D.B. Fearnley;L.F. Whyte;S.A. Carnoutsos;A.H. Cook

  • Multiple myeloma causes clonal T-cell immunosenescence: identification of potential novel targets for promoting tumour immunity and implications for checkpoint blockade.

    H Suen;R Brown;S Yang;C Weatherburn;C Weatherburn

  • PHENOTYPIC CHARACTERISATION OF THE DENDRITIC CELL INFILTRATE IN PROSTATE CANCER

    Andrew Troy;Peter Davidson;Christopher Atkinson;Derek Hart

  • Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83

    Brigitte Sénéchal;Adam M. Boruchov;John L. Reagan;Derek N. J. Hart

  • Expression of human DEC-205 (CD205) multilectin receptor on leukocytes.

    Masato Kato;Kylie J. McDonald;Seema Khan;Ian L. Ross

  • Distribution and quantitation of HLA-ABC and DR (Ia) antigens on human kidney and other tissues.

    Keryn A. Williams;Derek N. J. Hart;John W. Fabre;Peter J. Morris

  • Expression of multilectin receptors and comparative FITC–dextran uptake by human dendritic cells

    Masato Kato;Teresa K. Neil;David B. Fearnley;Alexander D. McLellan

  • Human dendritic cells activate T lymphocytes via a CD40: CD40 ligand‐dependent pathway

    Alexander D. McLellan;Riidiger V. Sorg;Lisa A. Williams;Derek N. J. Hart

  • CD83: Activation Marker for Antigen Presenting Cells and Its Therapeutic Potential.

    Ziduo Li;Xinsheng Ju;Pablo A. Silveira;Edward Abadir

  • CD molecules 2005: human cell differentiation molecules

    Heddy Zola;Bernadette Swart;Ian Nicholson;Bent Aasted

  • A soluble form of CD83 is released from activated dendritic cells and B lymphocytes, and is detectable in normal human sera

    Barry D. Hock;Masato Kato;Judith L. McKenzie;Derek N. J. Hart

  • Prolonged remission of longstanding systemic lupus erythematosus after autologous bone marrow transplant for non-Hodgkin's lymphoma.

    J. A. Snowden;W. N. Patton;J. L. O'donnell;E. E. Hannah

Frequent Co-Authors

Kenneth F. Bradstock
Kenneth F. Bradstock Westmead Hospital
Kelli P. A. MacDonald
Kelli P. A. MacDonald QIMR Berghofer Medical Research Institute
Anne M. Dickinson
Anne M. Dickinson Newcastle University
Geoffrey R. Hill
Geoffrey R. Hill Fred Hutchinson Cancer Research Center
P. Mark Hogarth
P. Mark Hogarth Burnet Institute
James D. Marks
James D. Marks University of California, San Francisco
Barbara Fazekas de St Groth
Barbara Fazekas de St Groth University of Sydney
Nigel J. Waterhouse
Nigel J. Waterhouse QIMR Berghofer Medical Research Institute
Matthew Collin
Matthew Collin Newcastle University
Eric J. Gowans
Eric J. Gowans University of Adelaide

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