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Alfred L. M. Bothwell

Alfred L. M. Bothwell

University of Arizona
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
14957
World Ranking
7878
National Ranking
3576

Alfred L. M. Bothwell publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Alfred L. M. Bothwell sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 221 publications — 58th percentile

58% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Alfred L. M. Bothwell D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Alfred L. M. Bothwell sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 68 D-Index — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Alfred L. M. Bothwell is affiliated with the University of Arizona in the United States and has contributed extensively to research primarily within the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields, notably Immunology, Oncology, Molecular Biology, Public Health, Environmental and Occupational Health, and Rheumatology.

The scientist's research focuses on diverse topics including Cancer Cells and Metastasis, Immune Cell Function and Interaction, Cancer Immunotherapy and Biomarkers, Phagocytosis and Immune Regulation, Wnt/β-catenin signaling in development and cancer, Research on Leishmaniasis Studies, and Immunotherapy and Immune Responses.

Notable recent papers authored or coauthored by the scientist include:

  • "Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis," 2021, Proceedings of the National Academy of Sciences
  • "Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1," 2021, iScience
  • "Trogocytosis-mediated immune evasion in the tumor microenvironment," 2025, Experimental & Molecular Medicine
  • "Dickkopf proteins in pathological inflammatory diseases," 2021, Journal of Leukocyte Biology
  • "Immune cells enhance Zika virus-mediated neurologic dysfunction in brain of mice with humanized immune systems," 2021, Developmental Neurobiology

Frequently collaborating with other researchers, Alfred L. M. Bothwell has repeatedly coauthored work with individuals including Anutr Sivakoses, Stephen E. Maher, Haley Q. Marcarian, Jae Hun Shin, and Olivia C. Ihedioha.

Their research has been published in recurring venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, eLife, PLoS ONE, and UNC Libraries, indicating a presence in both preprint repositories and peer-reviewed journals in immunology and related biomedical sciences.

Best Publications

  • Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.

    Alfred L.M. Bothwell;Michael Paskind;Michael Reth;Thereza Imanishi-Kari

  • Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3' ends.

    Frederick W. Alt;Alfred L.M. Bothwell;Michael Knapp;Edward Siden

  • STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity.

    Thomas Welte;Samuel S.M. Zhang;Tian Wang;Zhiyuan Zhang

  • T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity

    Maripat Corr;Alfred E. Slanetz;Lisa F. Boyd;Marie T. Jelonek

  • In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse.

    J. S. Schechner;A. K. Nath;L. Zheng;M. S. Kluger

  • An autoantibody to single‐stranded DNA: Comparison of the three‐dimensional structures of the unliganded fab and a deoxynucleotide–fab complex

    J. N. Herron;X. M. He;D. W. Ballard;P. R. Blier

  • Porcine aortic endothelial cells activate human T cells: direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28.

    Allen G. Murray;Mehran M. Khodedoust;Jordan S. Pober;Alfred L.M. Bothwell

  • Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation

    Jyoti Das;Guangwen Ren;Liying Zhang;Arthur I. Roberts

  • Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain

    Frederick W. Alt;Vincenzo Enea;Alfred L.M. Bothwell;David Baltimore

  • Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

    Wook-Jin Chae;Thomas F. Gibson;Daniel Zelterman;Liming Hao

  • Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59

    William C. Hahn;Elisabeth Menu;Alfred L. M. Bothwell;Peter J. Sims

  • Interplay between DNA repair and inflammation, and the link to cancer

    Dawit Kidane;Wook Jin Chae;Jennifer Czochor;Kristin A Eckert

  • Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments

    David G.T. Hesslein;David L. Pflugh;Dipanjan Chowdhury;Alfred L. M. Bothwell

  • Lateral diffusion of membrane-spanning and glycosylphosphatidylinositol-linked proteins: toward establishing rules governing the lateral mobility of membrane proteins.

    Fen Zhang;B. Crise;Bing Su;Y. Hou

  • The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases.

    Je-Min Choi;Alfred L. M. Bothwell

  • Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

    B. K. Al-Ramadi;M. T. Jelonek;L. F. Boyd;D. H. Margulies

  • Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds.

    Khuda Dad Khan;Ke Shuai;Glen Lindwall;Stephen E. Maher

  • Molecular basis of a mouse strain-specific anti-hapten response

    Dennis Y. Loh;Alfred L.M. Bothwell;Mary E. White-Scharf;Thereza Imanishi-Kari

  • Somatic variants of murine immunoglobulin lambda light chains.

    Alfred L. M. Bothwell;Michael Paskind;Michael Reth;Thereza Imanishi-Kari

  • Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA

    A. L.M. Bothwell;R. L. Garber;S. Altman

Frequent Co-Authors

Jordan S. Pober
Jordan S. Pober Yale University
Peter J. Sims
Peter J. Sims University of Rochester
David Baltimore
David Baltimore California Institute of Technology
Sidney Altman
Sidney Altman Yale University
James F. Leckman
James F. Leckman Yale University
David G. Schatz
David G. Schatz Yale University
Dean W. Ballard
Dean W. Ballard Vanderbilt University
Yufang Shi
Yufang Shi Soochow University
Bing Su
Bing Su Shanghai Jiao Tong University
Frederick W. Alt
Frederick W. Alt Boston Children's Hospital

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Additionally, anyone drawn to the pharmaceutical industry might consider enrolling in an online pharmacy school, which can lead to impactful roles in medication therapy, research, and patient safety. These pathways all align well with a foundation in Biology and Biochemistry, offering flexible options for professional growth.

Best Scientists Citing Alfred L. M. Bothwell

Jordan S. Pober

Jordan S. Pober

Yale University

Publications: 93

Frederick W. Alt

Frederick W. Alt

Boston Children's Hospital

Publications: 61

Klaus Rajewsky

Klaus Rajewsky

Max Delbrück Center for Molecular Medicine

Publications: 49

Mark M. Davis

Mark M. Davis

Stanford University

Publications: 35

Sidney Altman

Sidney Altman

Yale University

Publications: 34

David M. Kranz

David M. Kranz

University of Illinois at Urbana-Champaign

Publications: 31

Jeffrey L. Platt

Jeffrey L. Platt

University of Michigan–Ann Arbor

Publications: 30

David H. Sachs

David H. Sachs

Columbia University

Publications: 27

Garnett Kelsoe

Garnett Kelsoe

Duke University

Publications: 23

Ian A. Wilson

Ian A. Wilson

Scripps Research Institute

Publications: 22

David Baltimore

David Baltimore

California Institute of Technology

Publications: 22

Frank H. Ruddle

Frank H. Ruddle

Yale University

Publications: 21

Robert I. Lechler

Robert I. Lechler

King's College London

Publications: 20

W. Mark Saltzman

W. Mark Saltzman

Yale University

Publications: 19

David H. Margulies

David H. Margulies

National Institutes of Health

Publications: 19

Michael Reth

Michael Reth

University of Freiburg

Publications: 19

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