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Medicine

D-Index
89
Citations
29446
World Ranking
12679
National Ranking
6482

Overview

John S. Parks is affiliated with Wake Forest University in the United States. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with a focus on molecular biology, surgery, cancer research, immunology, and epidemiology.

The scientist's work covers a range of main topics including:

  • Cancer, Lipids, and Metabolism
  • Diet and Metabolism Studies
  • Cholesterol and Lipid Metabolism
  • Liver Disease Diagnosis and Treatment
  • Phagocytosis and Immune Regulation
  • Sphingolipid Metabolism and Signaling
  • Lipid Metabolism and Biosynthesis

Recent notable publications by John S. Parks include:

  • Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis, 2020, Molecular Cell
  • Dichloroacetate Reverses Sepsis-Induced Hepatic Metabolic Dysfunction, 2021, eLife
  • Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure, 2020, Circulation
  • Effect of Quercetin on Nonshivering Thermogenesis of Brown Adipose Tissue in High-Fat Diet-Induced Obese Mice, 2020, The Journal of Nutritional Biochemistry
  • Plasma Metabolomic Profiling in Subclinical Atherosclerosis: the Diabetes Heart Study, 2021, Cardiovascular Diabetology

John S. Parks frequently collaborates with a group of co-authors, including:

  • Elena Boudyguina
  • Cristina M. Furdui
  • Chia-Chi Chuang
  • Xuewei Zhu
  • Manal Zabalawi

The scientist's publications are often found in venues such as:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes
  • eLife
  • Journal of Clinical Investigation

John S. Parks' research integrates diverse areas bridging clinical medicine and molecular biology, with multiple contributions to topics related to metabolic processes in diseases like cancer, heart failure, and liver dysfunction. The emphasis on lipid metabolism and immune regulation also characterizes much of their published work across various journals and collaborations.

Best Publications

  • Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: Summary statement of the GH research society

    Kenneth M. Attie;Bengt Ake Bengtsson;Sandra L. Blethen;Werner Blum

  • Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone.

    Michael R. Adams;Jay R. Kaplan;Stephen B. Manuck;Donald R. Koritnik

  • Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism.

    Paul J. Godowski;David W. Leung;Lillian R. Meacham;John P. Galgani

  • LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response

    Steven J. Bensinger;Michelle N. Bradley;Sean B. Joseph;Noam Zelcer

  • Mutations in PROP1 cause familial combined pituitary hormone deficiency

    Wei Wu;Joy D. Cogan;Roland W. Pfäffle;Jeremy S. Dasen

  • Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

    Noelia A-Gonzalez;Steven J. Bensinger;Cynthia Hong;Susana Beceiro

  • Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.

    Liam R. Brunham;Janine K. Kruit;Jahangir Iqbal;Catherine Fievet

  • Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

    Jenelle M. Timmins;Ji Young Lee;Elena Boudyguina;Kimberly D. Kluckman

  • Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia.

    R. W. Pfäffle;G. E. DiMattia;J. S. Parks;M. R. Brown

  • Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.

    Liam R Brunham;Janine K Kruit;Terry D Pape;Jenelle M Timmins

  • Studies of low density lipoprotein molecular weight in human beings with coronary artery disease.

    John R. Crouse;Johns S. Parks;Harry M. Schey;Frederic R. Kahl

  • Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages

    Xuewei Zhu;Ji Young Lee;Jenelle M. Timmins;J. Mark Brown

  • An abundant dysfunctional apolipoprotein A1 in human atheroma

    Ying Huang;Joseph A DiDonato;Bruce S Levison;Dave Schmitt

  • Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol.

    Xuewei Zhu;John S. Owen;Martha D. Wilson;Haitao Li

  • Targeted Deletion of the Ileal Bile Acid Transporter Eliminates Enterohepatic Cycling of Bile Acids in Mice

    Paul A. Dawson;Jamie Haywood;Ann L. Craddock;Martha Wilson

  • Disintegration of phosphatidylcholine liposomes in plasma as a result of interaction with high-density lipoproteins

    Gerrit Scherphof;Frits Roerdink;Moseley Waite;John Parks

  • Intracellular Lipid Flux and Membrane Microdomains as Organizing Principles in Inflammatory Cell Signaling

    Michael B. Fessler;John S. Parks

  • Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

    Marit Westerterp;Andrew J. Murphy;Mi Wang;Tamara A. Pagler

  • Compared With Dietary Monounsaturated and Saturated Fat, Polyunsaturated Fat Protects African Green Monkeys From Coronary Artery Atherosclerosis

    Lawrence L. Rudel;John S. Parks;Janet K. Sawyer

  • Abstract 53: An Abundant Dysfunctional Apolipoprotein A1 in Human Atheroma

    Ying Huang;Joseph A DiDonato;Bruce S Levison;John S Parks

Frequent Co-Authors

Lawrence L. Rudel
Lawrence L. Rudel Wake Forest University
Barry I. Freedman
Barry I. Freedman Wake Forest University
Michael B. Fessler
Michael B. Fessler National Institutes of Health
Michael R. Hayden
Michael R. Hayden University of British Columbia
Michael J. Thomas
Michael J. Thomas Medical College of Wisconsin
Nobuyo Maeda
Nobuyo Maeda University of North Carolina at Chapel Hill
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Charles E. McCall
Charles E. McCall Wake Forest University
Stanley L. Hazen
Stanley L. Hazen Cleveland Clinic Lerner College of Medicine
Donald W. Bowden
Donald W. Bowden Wake Forest University

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