World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
12309
World Ranking
18585
National Ranking
7596

Overview

Rebecca E. Hussey is affiliated with the Dana-Farber Cancer Institute in the United States. Their research spans multiple disciplines including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology, indicating a multidisciplinary approach to biomedical science.

Their publication record features work published in the journal Proceedings of the National Academy of Sciences. One notable recent paper is titled Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing, published in 2021.

The scientist's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

The subfields of study highlighted in their work cover specialized areas such as:

  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Immunology

The key topics in their research include:

  • Monoclonal and Polyclonal Antibodies Research
  • Protein Structure and Dynamics
  • T-cell and B-cell Immunology

Rebecca E. Hussey has collaborated with several frequent co-authors, among them are:

  • Robert J. Mallis
  • Jonathan S. Duke-Cohan
  • Dibyendu Kumar Das
  • Aoi Akitsu
  • Adrienne Luoma

Their work focuses significantly on the immunology of T-cells, particularly the structural and functional aspects of immune receptors involved in ligand recognition and immune response modulation. The intersection of molecular design and immunological function is a recurring theme in their research.

Best Publications

  • An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

    Stefan C. Meuer;Rebecca E. Hussey;Marina Fabbi;David Fox

  • Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

    Stefan C. Meuer;Kathleen A. Fitzgerald;Rebecca E. Hussey;James C. Hodgdon

  • Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway

    Stefan C. Meuer;Rebecca E. Hussey;Doreen A. Cantrell;James C. Hodgdon

  • Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex.

    Ellis L. Reinherz;Stefan Meuer;Kathleen A. Fitzgerald;Rebecca E. Hussey

  • Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

    Stefan C. Meuer;Oreste Acuto;Rebecca E. Hussey;James C. Hodgdon

  • A soluble CD4 protein selectively inhibits HIV replication and syncytium formation.

    Rebecca E. Hussey;Neil E. Richardson;Mark Kowalski;Nicholas R. Brown

  • Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones.

    S C Meuer;J C Hodgdon;R E Hussey;J P Protentis

  • The crystal structure of a T cell receptor in complex with peptide and MHC class II

    Ellis L. Reinherz;Kemin Tan;Lei Tang;Petra Kern

  • The human T cell receptor: Appearance in ontogeny and biochemical relationship of α and β subunits on IL-2 dependent clones and T cell tumors

    Oreste Acuto;Rebecca E. Hussey;Kathleen A. Fitzgerald;Jeffrey P. Protentis

  • Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.

    E L Reinherz;C Morimoto;K A Fitzgerald;R E Hussey

  • Ta1, a novel 105 KD human T cell activation antigen defined by a monoclonal antibody.

    D A Fox;R E Hussey;K A Fitzgerald;O Acuto

  • A monoclonal antibody blocking human T cell function

    Ellis L. Reinherz;Rebecca E. Hussey;Stuart F. Schlossman

  • Surface structures involved in target recognition by human cytotoxic T lymphocytes

    SC Meuer;RE Hussey;JC Hodgdon;T Hercend

  • Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime

    Dibyendu Kumar Das;Yinnian Feng;Robert J. Mallis;Xiaolong Li

  • Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding

    Linda K. Clayton;Rebecca E. Hussey;Ruth Steinbrich;Hema Ramachandran

  • Reconstitution after transplantation with T-lymphocyte-depleted HLA haplotype-mismatched bone marrow for severe combined immunodeficiency.

    Ellis L. Reinherz;Raif Geha;Joel M. Rappeport;Marjorie Wilson

  • Activation of human thymocytes via the 50KD T11 sheep erythrocyte binding protein induces the expression of interleukin 2 receptors on both T3+ and T3- populations.

    D A Fox;R E Hussey;K A Fitzgerald;A Bensussan

  • Structural Basis of CD8 Coreceptor Function Revealed by Crystallographic Analysis of a Murine CD8αα Ectodomain Fragment in Complex with H-2Kb

    Petra S. Kern;Mai-kun Teng;Alex Smolyar;Jin-huan Liu

  • Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones.

    Jerome Ritz;Thomas J. Campen;Reinhold E. Schmidt;Hans Dieter Royer

  • Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.

    J Wang;K Lim;A Smolyar;M Teng;M Teng

Frequent Co-Authors

Ellis L. Reinherz
Ellis L. Reinherz Harvard University
Stuart F. Schlossman
Stuart F. Schlossman Harvard University
Stefan Meuer
Stefan Meuer Heidelberg University
Oreste Acuto
Oreste Acuto University of Oxford
Jia-huai Wang
Jia-huai Wang Harvard University
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Gerhard Wagner
Gerhard Wagner Harvard University
Stanley G. Nathenson
Stanley G. Nathenson Albert Einstein College of Medicine
David A. Cooper
David A. Cooper University of New South Wales

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