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Giuseppe Bifulco

Giuseppe Bifulco

D-Index & Metrics

Chemistry

D-Index
60
Citations
12233
World Ranking
9738
National Ranking
288

Overview

Giuseppe Bifulco is affiliated with the University of Salerno in Italy. Their research spans several key areas within biochemistry, genetics, molecular biology, and medicine, contributing extensively to the understanding of molecular and pharmacological processes.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad areas, their more specific subfields of interest are:

  • Molecular Biology
  • Pharmacology
  • Organic Chemistry
  • Biochemistry
  • Plant Science

The primary research topics Giuseppe Bifulco has focused on include:

  • Protein Degradation and Inhibitors
  • Inflammatory mediators and NSAID effects
  • Natural product bioactivities and synthesis
  • Computational Drug Discovery Methods
  • Eicosanoids and Hypertension Pharmacology
  • Multiple Myeloma Research and Treatments
  • Microbial Natural Products and Biosynthesis

Giuseppe Bifulco has published frequently in several scientific journals. The venues with the highest numbers of their publications are:

  • European Journal of Medicinal Chemistry
  • ChemMedChem
  • Journal of Natural Products
  • Molecules
  • Journal of Medicinal Chemistry

Recent selected papers include:

  • "DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data", 2020, The Journal of Organic Chemistry
  • "Insights into the Ligand Binding to Bromodomain-Containing Protein 9 (BRD9): A Guide to the Selection of Potential Binders by Computational Methods", 2021, Molecules
  • "Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells", 2020, ACS Omega
  • "Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches", 2020, European Journal of Organic Chemistry
  • "Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization", 2021, European Journal of Medicinal Chemistry

Among their frequent collaborators, the most commonly appearing coauthors are:

  • Gianluigi Lauro
  • Maria Giovanna Chini
  • Stefania Terracciano
  • Ines Bruno
  • Pietro Campiglia

Best Publications

  • Determination of Relative Configuration in Organic Compounds by NMR Spectroscopy and Computational Methods

    Giuseppe Bifulco;Paolo Dambruoso;Luigi Gomez-Paloma;Raffaele Riccio

  • The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

    Sabrina Cipriani;Andrea Mencarelli;Maria Giovanna Chini;Eleonora Distrutti

  • Structure validation of natural products by quantum-mechanical GIAO calculations of 13C NMR chemical shifts.

    Giampaolo Barone;Luigi Gomez-Paloma;Dario Duca;Arturo Silvestri

  • New bisindole alkaloids of the topsentin and hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei.

    Agostino Casapullo;Giuseppe Bifulco;Ines Bruno;Raffaele Riccio

  • Further Brominated Bis- and Tris-Indole Alkaloids from the Deep-Water New Caledonian Marine Sponge Orina sp.

    Giuseppe Bifulco;Ines Bruno;Raffaele Riccio;Jacques Lavayre

  • Comparison of different theory models and basis sets in the calculation of 13C NMR chemical shifts of natural products

    Paola Cimino;Luigi Gomez-Paloma;Dario Duca;Raffaele Riccio

  • Determination of the relative stereochemistry of flexible organic compounds by Ab initio methods: conformational analysis and Boltzmann-averaged GIAO 13C NMR chemical shifts.

    Giampaolo Barone;Dario Duca;Arturo Silvestri;Luigi Gomez-Paloma

  • Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase−1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents

    Rosa De Simone;Maria Giovanna Chini;Ines Bruno;Raffaele Riccio

  • Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4

    Luigi Martino;Ada Virno;Bruno Pagano;Antonella Virgilio

  • Dragmacidin F: A New Antiviral Bromoindole Alkaloid from the Mediterranean Sponge Halicortex sp.

    Adele Cutignano;Giuseppe Bifulco;Ines Bruno;Agostino Casapullo

  • Halipeptins A and B: two novel potent anti-inflammatory cyclic depsipeptides from the Vanuatu marine sponge Haliclona species.

    Antonio Randazzo;Giuseppe Bifulco;Clelia Giannini;Mariarosaria Bucci

  • Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ.

    Alberto Plaza;Jessica L. Keffer;Giuseppe Bifulco;John R. Lloyd

  • Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry.

    Alberto Plaza;Giuseppe Bifulco;Jessica L. Keffer;John R. Lloyd

  • Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors.

    Rosanna Filosa;Antonella Peduto;Simone Di Micco;Paolo de Caprariis

  • A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry.

    Giampiero Colombano;Cristina Travelli;Ubaldina Galli;Antonio Caldarelli

  • Quantum Mechanical Calculation of NMR Parameters in the Stereostructural Determination of Natural Products

    Simone Di Micco;Maria Giovanna Chini;Raffaele Riccio;Giuseppe Bifulco

  • Activation and mitochondrial translocation of protein kinase Cδ are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells

    Matilde Caruso;Maria Alessandra Maitan;Giuseppe Bifulco;Claudia Miele

  • Tolaasins A--E, five new lipodepsipeptides produced by Pseudomonas tolaasii.

    Carla Bassarello;Silvia Lazzaroni;Giuseppe Bifulco;Pietro Lo Cantore

  • Quantitative NMR-derived interproton distances combined with quantum mechanical calculations of 13C chemical shifts in the stereochemical determination of conicasterol F, a nuclear receptor ligand from Theonella swinhoei.

    Maria Giovanna Chini;Catharine R Jones;Angela Zampella;Maria Valeria D'Auria

  • The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma.

    Maurizio Guida;Alessia Ligresti;Daniele De Filippis;Alessandra D'Amico

  • Molecular insights into azumamide e histone deacetylases inhibitory activity.

    Nakia Maulucci;Maria Giovanna Chini;Simone Di Micco;Irene Izzo

Frequent Co-Authors

Raffaele Riccio
Raffaele Riccio University of Salerno
Stefano Fiorucci
Stefano Fiorucci University of Perugia
Sonia Piacente
Sonia Piacente University of Salerno
Cécile Debitus
Cécile Debitus University of Western Brittany
Nunziatina De Tommasi
Nunziatina De Tommasi University of Salerno
Maria Chiara Monti
Maria Chiara Monti University of Salerno
Carole A. Bewley
Carole A. Bewley National Institutes of Health
Pietro Campiglia
Pietro Campiglia University of Salerno
Maurizio Taddei
Maurizio Taddei University of Siena
Walter J. Chazin
Walter J. Chazin Vanderbilt University

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