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Biology and Biochemistry

D-Index
57
Citations
29371
World Ranking
13508
National Ranking
123

Overview

Mario Gimona is affiliated with Paracelsus Medical University in Austria and has contributed extensively to research in biochemistry, genetics, and molecular biology, with a particular focus on extracellular vesicles and related biomedical fields.

The primary areas of study covered in their research include:

  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • RNA Interference and Gene Delivery
  • Nanopore and Nanochannel Transport Studies
  • Mesenchymal stem cell research
  • Tissue Engineering and Regenerative Medicine
  • Lipid Membrane Structure and Behavior

Work spans subfields such as molecular biology, surgery, cancer research, biomedical engineering, and genetics.

Gimona's publication record includes several papers in reputable venues, with notable recent papers including:

  • Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles, 2021, Cytotherapy
  • International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19, 2020, Cytotherapy
  • Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial, 2021, The Lancet Neurology
  • First-in-human intracochlear application of human stromal cell-derived extracellular vesicles, 2021, Journal of Extracellular Vesicles
  • Large-scale production of extracellular vesicles: Report on the "massivEVs" ISEV workshop, 2022, Journal of Extracellular Biology

Frequent publication venues for Gimona include:

  • Cytotherapy
  • Journal of Extracellular Vesicles
  • Journal of Extracellular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nanoscale

The scientist has collaborated extensively with various co-authors, most frequently with:

  • Eva Rohde
  • Sai Kiang Lim
  • Athanasia Warnecke
  • Johannes Grillari
  • Marta Tortajada

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Biological properties of extracellular vesicles and their physiological functions

    María Yáñez-Mó;Pia R.-M. Siljander;Zoraida Andreu;Apolonija Bedina Zavec

  • Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  • Assembly and biological role of podosomes and invadopodia.

    Mario Gimona;Roberto Buccione;Sara A Courtneidge;Stefan Linder

  • Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications

    Kenneth W. Witwer;Bas W.M. Van Balkom;Stefania Bruno;Andre Choo

  • Functional plasticity of CH domains

    Mario Gimona;Kristina Djinovic-Carugo;Wolfgang J. Kranewitter;Steven J. Winder

  • Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles

    Agnes T Reiner;Kenneth W Witwer;Bas Wm van Balkom;Joel de Beer

  • Calponin and SM22 as differentiation markers of smooth muscle: spatiotemporal distribution during avian embryonic development

    Jean-Loup Duband;Mario Gimona;Marta Scatena;Saverio Sartore

  • Manufacturing of Human Extracellular Vesicle-Based Therapeutics for Clinical Use

    Mario Gimona;Karin Pachler;Sandra Laner-Plamberger;Katharina Schallmoser

  • Smooth muscle specific expression of calponin

    Mario Gimona;Monika Herzog;Joël Vandekerckhove;John Victor Small

  • The cytoskeleton of the vertebrate smooth muscle cell

    J V Small;M Gimona

  • Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells.

    Mario Gimona;Irina Kaverina;Guenter P. Resch;Emmanuel Vignal

  • A Good Manufacturing Practice-grade standard protocol for exclusively human mesenchymal stromal cell-derived extracellular vesicles.

    Karin Pachler;Thomas Lener;Doris Streif;Zsuzsanna A. Dunai

  • THE SINGLE CH DOMAIN OF CALPONIN IS NEITHER SUFFICIENT NOR NECESSARY FOR F-ACTIN BINDING

    Mario Gimona;Renu Mital

  • Manufacturing and characterization of extracellular vesicles from umbilical cord-derived mesenchymal stromal cells for clinical testing.

    Eva Rohde;Karin Pachler;Mario Gimona

  • Protein Kinase C Induces Actin Reorganization via a Src- and Rho-dependent Pathway

    Dominique Brandt;Mario Gimona;Meike Hillmann;Hermann Haller

  • Actin isoform compartments in chicken gizzard smooth muscle cells

    A.J. North;M. Gimona;Z. Lando;J.V. Small

  • Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells

    A.J North;Mario Gimona;R.A Cross;J.V Small

  • Normalization of nomenclature for peptide motifs as ligands of modular protein domains.

    Rein Aasland;Charles Abrams;Christophe Ampe;Linda J. Ball

  • Applying extracellular vesicles based therapeutics in clinical trials

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

Frequent Co-Authors

Bernd Giebel
Bernd Giebel University of Duisburg-Essen
Sai Kiang Lim
Sai Kiang Lim Agency for Science, Technology and Research
J. Victor Small
J. Victor Small Austrian Academy of Sciences
Jan Lötvall
Jan Lötvall University of Gothenburg
Andrew F. Hill
Andrew F. Hill Victoria University
Joël Vandekerckhove
Joël Vandekerckhove Ghent University
Hernando A. del Portillo
Hernando A. del Portillo University of Barcelona
Kenneth W. Witwer
Kenneth W. Witwer Johns Hopkins University
Marca H. M. Wauben
Marca H. M. Wauben Utrecht University

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