D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 74 Citations 25,900 130 World Ranking 743 National Ranking 409

Research.com Recognitions

Awards & Achievements

2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Member of the European Molecular Biology Organization (EMBO)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Sara A. Courtneidge mainly focuses on Proto-oncogene tyrosine-protein kinase Src, Cell biology, Receptor tyrosine kinase, SH3 domain and Molecular biology. Her Proto-oncogene tyrosine-protein kinase Src research incorporates elements of Tyrosine kinase and Platelet-derived growth factor receptor. Her Tyrosine kinase research is multidisciplinary, incorporating perspectives in ROR1 and Phosphorylation.

Her studies in Cell biology integrate themes in fields like Podosome, Invadopodia and Invadopodium. She focuses mostly in the field of Receptor tyrosine kinase, narrowing it down to topics relating to Growth factor receptor and, in certain cases, Actin cytoskeleton, Insulin-like growth factor 1 receptor, Epidermal growth factor receptor and Epidermal growth factor. Her SH3 domain research includes themes of DAAM1, SH2 domain, Rho-associated protein kinase and GTPase binding.

Her most cited work include:

  • The ADAMs family of metalloproteases: multidomain proteins with multiple functions (916 citations)
  • A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation (913 citations)
  • The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function. (699 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Proto-oncogene tyrosine-protein kinase Src, Cell biology, Tyrosine kinase, Invadopodia and SH3 domain. Her study in Proto-oncogene tyrosine-protein kinase Src is interdisciplinary in nature, drawing from both Molecular biology and Receptor tyrosine kinase. Her research integrates issues of ROR1 and Tyrosine phosphorylation in her study of Receptor tyrosine kinase.

Her Cell biology research includes elements of Podosome and Cortactin. Her study looks at the intersection of Tyrosine kinase and topics like Phosphorylation with Tyrosine. Sara A. Courtneidge combines subjects such as Extracellular matrix and Cancer research with her study of Invadopodia.

She most often published in these fields:

  • Proto-oncogene tyrosine-protein kinase Src (50.36%)
  • Cell biology (46.76%)
  • Tyrosine kinase (29.50%)

What were the highlights of her more recent work (between 2011-2021)?

  • Invadopodia (25.18%)
  • Cell biology (46.76%)
  • Cancer research (18.71%)

In recent papers she was focusing on the following fields of study:

The scientist’s investigation covers issues in Invadopodia, Cell biology, Cancer research, Extracellular matrix and Cancer cell. Her Invadopodia study combines topics in areas such as Cell, Cortactin, Signal transducing adaptor protein and Tumor progression. Her Cell biology research is multidisciplinary, relying on both Podosome and Endosome.

Sara A. Courtneidge interconnects Tyrosine kinase and Cell migration in the investigation of issues within Podosome. Her work in Estrogen addresses issues such as Transcription factor, which are connected to fields such as Proto-oncogene tyrosine-protein kinase Src, Kinase, Stimulation, RNA-binding protein and Stem cell. Her Kinase research integrates issues from Molecular biology and Gene knockdown.

Between 2011 and 2021, her most popular works were:

  • Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis. (203 citations)
  • Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia (106 citations)
  • Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival (84 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Her primary scientific interests are in Invadopodia, Cell biology, Podosome, Tumor progression and Cancer cell. Her Cell biology study integrates concerns from other disciplines, such as Heparin-binding EGF-like growth factor and Paracrine signalling. Her Podosome study combines topics from a wide range of disciplines, such as Cell Surface Extension, Extracellular matrix, Cell migration and Signal transducing adaptor protein.

Sara A. Courtneidge has researched Tumor progression in several fields, including Tumor microenvironment and Prostate cancer. Her Prostate cancer research is multidisciplinary, relying on both Tyrosine kinase and Proto-oncogene tyrosine-protein kinase Src, Phosphorylation. Her Cancer cell research focuses on Metastasis and how it relates to Cancer research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The ADAMs family of metalloproteases: multidomain proteins with multiple functions

Darren F. Seals;Sara A. Courtneidge.
Genes & Development (2003)

1517 Citations

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function.

Danielle A. Murphy;Sara A. Courtneidge.
Nature Reviews Molecular Cell Biology (2011)

1217 Citations

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

Ivan Dikic;George Tokiwa;Sima Lev;Sara A. Courtneidge.
Nature (1996)

1174 Citations

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase.

Masayuki Otsu;Ian Hiles;Ivan Gout;Michael J. Fry.
Cell (1991)

913 Citations

Phosphatidylinositol 3-kinase : structure and expression of the 110 kd catalytic subunit

Ian D. Hiles;Masayuki Otsu;Stefano Volinia;Michael J. Fry.
Cell (1992)

905 Citations

SU6656, a Selective Src Family Kinase Inhibitor, Used To Probe Growth Factor Signaling

Robert A. Blake;Martin A. Broome;Xiangdong Liu;Jianming Wu.
Molecular and Cellular Biology (2000)

837 Citations

Association between the PDGF receptor and members of the src family of tyrosine kinases.

Robert M. Kypta;Yves Goldberg;Emin T. Ulug;Sara A. Courtneidge.
Cell (1990)

809 Citations

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

Tammy Bowman;Martin A. Broome;Dominic Sinibaldi;Walker Wharton.
Proceedings of the National Academy of Sciences of the United States of America (2001)

667 Citations

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

Leonardo Elia;Manuela Quintavalle;Jianlin Zhang;Riccardo Contu.
Cell Death & Differentiation (2009)

642 Citations

Polyoma virus transforming protein associates with the product of the c-src cellular gene

Sara A. Courtneidge;Alan E. Smith.
Nature (1983)

613 Citations

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