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Computer Science

D-Index
41
Citations
11630
World Ranking
8630
National Ranking
3699

Overview

Denis Fourches is a researcher affiliated with North Carolina State University in the United States. Their body of work primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a total of 33 publications.

Within these broader fields, Fourches has contributed extensively to various subfields, including Molecular Biology, Computational Theory and Mathematics, Pharmacology, Materials Chemistry, and Organic Chemistry.

Their research topics cover several distinct areas:

  • Computational Drug Discovery Methods
  • Machine Learning in Materials Science
  • Metabolomics and Mass Spectrometry Studies
  • Click Chemistry and Applications
  • Chemical Synthesis and Analysis
  • Estrogen and related hormone effects
  • Effects and risks of endocrine disrupting chemicals

Fourches has published multiple papers that have contributed to scientific literature:

  • QSAR without borders, 2020, Chemical Society Reviews
  • A critical overview of computational approaches employed for COVID-19 drug discovery, 2021, Chemical Society Reviews
  • CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity, 2020, Environmental Health Perspectives
  • Inductive transfer learning for molecular activity prediction: Next-Gen QSAR Models with MolPMoFiT, 2020, Journal of Cheminformatics
  • CATMoS: Collaborative Acute Toxicity Modeling Suite, 2021, Environmental Health Perspectives

Frequent co-authors collaborating with Fourches include:

  • Alexander Tropsha (39 publications)
  • Eugene Muratov (25 publications)
  • Carolina Horta Andrade (13 publications)
  • Alexandre Varnek (11 publications)
  • Vinícius M. Alves (11 publications)

Their work has been frequently published in several venues, notably:

  • UNC Libraries (27 publications)
  • OPAL (Open@LaTrobe) (La Trobe University) (6 publications)
  • Environmental Health Perspectives (4 publications)
  • Chemical Society Reviews (3 publications)
  • Journal of Cheminformatics (2 publications)

Best Publications

  • QSAR Modeling: Where have you been? Where are you going to?

    Artem Cherkasov;Eugene N. Muratov;Eugene N. Muratov;Denis Fourches;Alexandre Varnek

  • Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research

    Denis Fourches;Eugene N. Muratov;Alexander Tropsha

  • QSAR without borders

    Eugene N. Muratov;Eugene N. Muratov;Jürgen Bajorath;Robert P. Sheridan;Igor V. Tetko

  • Critical Assessment of QSAR Models of Environmental Toxicity against Tetrahymena pyriformis: Focusing on Applicability Domain and Overfitting by Variable Selection

    Igor V. Tetko;Iurii Sushko;Anil Kumar Pandey;Hao Zhu

  • Quantitative Nanostructure−Activity Relationship Modeling

    Denis Fourches;Dongqiuye Pu;Carlos Tassa;Ralph Weissleder

  • Materials Cartography: Representing and Mining Materials Space Using Structural and Electronic Fingerprints

    Olexandr Isayev;Denis Fourches;Eugene N. Muratov;Corey Oses

  • CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

    Kamel Mansouri;Ahmed Abdelaziz;Aleksandra Rybacka;Alessandra Roncaglioni

  • Comprehensive characterization of the Published Kinase Inhibitor Set

    Jonathan M. Elkins;Vita Fedele;Marta Szklarz;Kamal R. Abdul Azeez

  • Combinatorial QSAR Modeling of Chemical Toxicants Tested against Tetrahymena pyriformis

    Hao Zhu;Alexander Tropsha;Denis Fourches;Alexandre Varnek

  • Trust, but Verify II: A Practical Guide to Chemogenomics Data Curation

    Denis Fourches;Eugene N. Muratov;Alexander Tropsha

  • Applicability domains for classification problems: Benchmarking of distance to models for Ames mutagenicity set.

    Iurii Sushko;Sergii Novotarskyi;Robert Körner;Anil Kumar Pandey

  • Substructural fragments: an universal language to encode reactions, molecular and supramolecular structures

    Alexandre Varnek;Denis Fourches;Frank Hoonakker;Vitaly P. Solov'ev

  • ISIDA - Platform for Virtual Screening Based on Fragment and Pharmacophoric Descriptors

    Alexandre Varnek;Denis Fourches;Dragos Horvath;Olga Klimchuk

  • Materials Cartography: Representing and Mining Material Space Using Structural and Electronic Fingerprints

    Olexandr Isayev;Denis Fourches;Eugene N. Muratov;Corey Oses

  • Predicting Drug-induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

    Yen Low;Takeki Uehara;Yohsuke Minowa;Hiroshi Yamada

  • Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity.

    Rodolpho C. Braga;Vinicius M. Alves;Meryck F. B. Silva;Eugene Muratov

  • Curation of chemogenomics data.

    Denis Fourches;Eugene Muratov;Alexander Tropsha

  • CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity.

    Kamel Mansouri;Nicole Kleinstreuer;Ahmed M. Abdelaziz;Domenico Alberga

  • A critical overview of computational approaches employed for COVID-19 drug discovery.

    Eugene N Muratov;Rommie Amaro;Carolina H Andrade;Nathan Brown

  • Cheminformatics Analysis of Assertions Mined from Literature that Describe Drug-Induced Liver Injury in Different Species

    Denis Fourches;Julie C. Barnes;Nicola C. Day;Paul Bradley

Frequent Co-Authors

Alexander Tropsha
Alexander Tropsha University of North Carolina at Chapel Hill
Eugene N. Muratov
Eugene N. Muratov University of North Carolina at Chapel Hill
Igor V. Tetko
Igor V. Tetko Helmholtz Zentrum München
Hao Zhu
Hao Zhu Rutgers, The State University of New Jersey
Dragos Horvath
Dragos Horvath University of Strasbourg
David A. Winkler
David A. Winkler La Trobe University
Olexandr Isayev
Olexandr Isayev Carnegie Mellon University
Antony J. Williams
Antony J. Williams Environmental Protection Agency
Viviana Consonni
Viviana Consonni University of Milano-Bicocca
Sean Ekins
Sean Ekins University of Arizona

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