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Stephen P. Bell

Stephen P. Bell

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
21629
World Ranking
11117
National Ranking
4812

Research.com Recognitions

  • 2017 - Member of the National Academy of Sciences

Overview

Stephen P. Bell is affiliated with MIT in the United States and conducts research primarily in the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields, including Molecular Biology, Cell Biology, Cardiology and Cardiovascular Medicine, Clinical Biochemistry, and Biochemistry.

The main topics addressed in their research include DNA Repair Mechanisms, Microtubule and mitosis dynamics, Fungal and yeast genetics research, Metabolism and Genetic Disorders, CRISPR and Genetic Engineering, Amino Acid Enzymes and Metabolism, and DNA and Nucleic Acid Chemistry.

Frequent coauthors in their publications include Jeff Gelles, Larry J. Friedman, Shalini Gupta, Audra L. Amasino, and Lorraine De Jesús-Kim.

Stephen P. Bell has published extensively in several venues, with notable frequent publication outlets being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Frontiers in Physiology
  • UNC Libraries
  • Zenodo (CERN European Organization for Nuclear Research)

Examples of recent papers authored or coauthored by Stephen P. Bell include:

  • DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7, 2021, eLife
  • Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing, 2023, Proceedings of the National Academy of Sciences
  • Distinct RPA functions promote eukaryotic DNA replication initiation and elongation, 2023, Nucleic Acids Research
  • Changing protein-DNA interactions promote ORC binding-site exchange during replication origin licensing, 2023, Proceedings of the National Academy of Sciences
  • Preparing Excitable Cardiac Papillary Muscle and Cardiac Slices for Functional Analyses, 2022, Frontiers in Physiology

Stephen P. Bell was recognized as a Member of the National Academy of Sciences in 2017.

Best Publications

  • DNA replication in eukaryotic cells

    Stephen P. Bell;Anindya Dutta

  • Purification and biochemical characterization of the promoter-specific transcription factor, Sp1

    Michael R. Briggs;James T. Kadonaga;Stephen P. Bell;Robert Tjian

  • ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex.

    Stephen P. Bell;Bruce Stillman

  • Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase

    Oscar M Aparicio;Deborah M Weinstein;Stephen P Bell

  • Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

    Hans-Michael Jantzen;Arie Admon;Stephen P. Bell;Robert Tjian

  • Initiation of DNA replication in eukaryotic cells.

    Anindya Dutta;Stephen P. Bell

  • Yeast origin recognition complex functions in transcription silencing and DNA replication

    Stephen P. Bell;Ryuji Kobayashi;Bruce Stillman

  • Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins

    John J. Wyrick;Jennifer G. Aparicio;Ting Chen;John D. Barnett

  • Chromosome Duplication in Saccharomyces cerevisiae.

    Stephen P Bell;Karim Labib

  • Polymerases and the Replisome: Machines within Machines

    Tania A Baker;Stephen P Bell

  • Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis

    SP Bell;RM Learned;HM Jantzen;R Tjian

  • Conserved nucleosome positioning defines replication origins

    Matthew L. Eaton;Kyriaki Galani;Sukhyun Kang;Stephen P. Bell

  • The origin recognition complex: from simple origins to complex functions

    Stephen P. Bell

  • Sequential ATP Hydrolysis by Cdc6 and ORC Directs Loading of the Mcm2-7 Helicase

    John C.W. Randell;Jayson L. Bowers;Heather K. Rodríguez;Stephen P. Bell

  • Nucleosomes positioned by ORC facilitate the initiation of DNA replication.

    J.Russell Lipford;Stephen P Bell

  • Coordination of replication and transcription along a Drosophila chromosome

    David M. MacAlpine;Heather K. Rodríguez;Stephen P. Bell

  • Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

    Ryan C. Heller;Sukhyun Kang;Wendy M. Lam;Shuyan Chen

  • The multidomain structure of Orc1 p reveals similarity to regulators of DNA replication and transcriptional silencing

    Stephen P. Bell;Stephen P. Bell;Jay Mitchell;Jess Leber;Ryuji Kobayashi

  • Coordinate Binding of ATP and Origin DNA Regulates the ATPase Activity of the Origin Recognition Complex

    Richard D Klemm;Richard J Austin;Stephen P Bell

  • Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

    Oscar M. Aparicio;Anita M. Stout;Stephen P. Bell

Frequent Co-Authors

Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Ryuji Kobayashi
Ryuji Kobayashi The University of Texas MD Anderson Cancer Center
Anindya Dutta
Anindya Dutta University of Alabama at Birmingham
Jeff Gelles
Jeff Gelles Brandeis University
Jack D. Griffith
Jack D. Griffith University of North Carolina at Chapel Hill
Dirk Schübeler
Dirk Schübeler Friedrich Miescher Institute
Michael R. Botchan
Michael R. Botchan University of California, Berkeley
Terence P. Speed
Terence P. Speed Walter and Eliza Hall Institute of Medical Research

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