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Toshiki Tsurimoto

Toshiki Tsurimoto

D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
10284
World Ranking
18868
National Ranking
1356

Overview

Toshiki Tsurimoto is a researcher affiliated with Kyushu University in Japan, whose work primarily focuses on biochemistry, genetics, and molecular biology. Their research contributions span several subfields, including molecular biology, oncology, genetics, and cell biology.

The scientist's main research topics include:

  • DNA Repair Mechanisms
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Genetics and Neurodevelopmental Disorders
  • CRISPR and Genetic Engineering
  • Cancer-related Molecular Pathways
  • Genomics and Chromatin Dynamics

Toshiki Tsurimoto has published research in several renowned scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • eLife
  • Molecular Cancer Research
  • Journal of Biological Chemistry

Representative papers authored or co-authored by Toshiki Tsurimoto include:

  • DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 Status, 2020, Molecular Cancer Research
  • The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5, 2023, eLife
  • The proofreading exonuclease of leading-strand DNA polymerase epsilon prevents replication fork collapse at broken template strands, 2023, Nucleic Acids Research
  • DNA Polymerase Delta, 2020, Definitions
  • Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts, 2024, Nucleic Acids Research

The scientist frequently collaborates with several co-authors including:

  • Yoshitaka Kawasoe
  • Tatsuro Takahashi
  • Ryota Miyashita
  • Atsuya Nishiyama
  • Yoshie Chiba

Best Publications

  • Rad18 guides polη to replication stalling sites through physical interaction and PCNA monoubiquitination

    Kenji Watanabe;Satoshi Tateishi;Michio Kawasuji;Toshiki Tsurimoto

  • Regulation of DNA-replication origins during cell-cycle progression.

    Katsuhiko Shirahige;Yuji Hori;Katsuya Shiraishi;Minoru Yamashita

  • Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin.

    Toshiki Tsurimoto;Thomas Melendy;Bruce Stillman

  • Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins.

    T Tsurimoto;B Stillman

  • Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

    Hideo Nishitani;Nozomi Sugimoto;Vassilis Roukos;Yohsuke Nakanishi

  • Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis.

    Toshiki Tsurimoto;B. Stillman

  • CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1Cdt2 Pathway during S Phase and after UV Irradiation

    Hideo Nishitani;Hideo Nishitani;Yasushi Shiomi;Hiroka Iida;Masato Michishita

  • Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.

    Toshiki Tsurimoto;Bruce Stillman

  • Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, alpha and delta.

    Toshiki Tsurimoto;B. Stillman

  • Stable expression and replication of hepatitis B virus genome in an integrated state in a human hepatoma cell line transfected with the cloned viral DNA.

    Toshiki Tsurimoto;Asao Fujiyama;Kenichi Matsubara

  • PCNA binding proteins.

    Toshiki Tsurimoto

  • Characteristics of purified recA protein and the regulation of its synthesis in vivo.

    T. Ogawa;H. Wabiko;Toshiki Tsurimoto;T. Horii

  • Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro.

    T Tsurimoto;B Stillman

  • Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

    Yoko Hayashi-Takanaka;Kazuo Yamagata;Teruhiko Wakayama;Timothy J. Stasevich

  • Structure-Function Relationship of the Eukaryotic DNA Replication Factor, Proliferating Cell Nuclear Antigen

    Kotaro Fukuda;Kotaro Fukuda;Hiroshi Morioka;Sayuri Imajou;Soichiro Ikeda

  • The mode of hepatitis B virus DNA integration in chromosomes of human hepatocellular carcinoma.

    T Nagaya;T Nakamura;T Tokino;T Tsurimoto

  • Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription.

    Hirotake Kitaura;Minako Shinshi;Yasuko Uchikoshi;Takashi Ono

  • PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

    Tetsuo Iida;Isao Suetake;Shoji Tajima;Hiroshi Morioka

  • PCNA, a multifunctional ring on DNA.

    Toshiki Tsurimoto

  • Three envelope proteins of hepatitis B virus: large S, middle S, and major S proteins needed for the formation of Dane particles.

    K Ueda;T Tsurimoto;K Matsubara

Frequent Co-Authors

Kenichi Matsubara
Kenichi Matsubara Osaka University
Chikashi Obuse
Chikashi Obuse Osaka University
Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Tsutomu Katayama
Tsutomu Katayama Kyushu University
Katsuhiko Shirahige
Katsuhiko Shirahige University of Tokyo
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Shunichi Takeda
Shunichi Takeda Shenzhen University
Hisao Masai
Hisao Masai Tokyo Metropolitan Institute of Medical Science
Julian E. Sale
Julian E. Sale MRC Laboratory of Molecular Biology

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