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Molecular Biology

D-Index
45
Citations
7143
World Ranking
2867
National Ranking
1368

Overview

Brad A. Amendt is affiliated with the University of Iowa in the United States and specializes in the field of Biochemistry, Genetics and Molecular Biology, with a notable focus on Molecular Biology. Their research spans various subfields including Cancer Research, Genetics, Rheumatology, and Biomedical Engineering.

Their work encompasses a range of topics that include:

  • MicroRNA in disease regulation
  • Dental development and anomalies
  • RNA modifications and cancer
  • Cleft Lip and Palate Research
  • Bone and Dental Protein Studies
  • Cancer-related gene regulation
  • Cancer-related molecular mechanisms research

Among the recent papers published by Brad A. Amendt are several that address important aspects of dental and molecular biology, including:

  • Gene-environment interaction in molar-incisor hypomineralization (2021, PLoS ONE)
  • Pitx2-Sox2-Lef1 interactions specify progenitor oral/dental epithelial cell signaling centers (2020, Development)
  • MicroRNA function in craniofacial bone formation, regeneration and repair (2020, Bone)
  • Plasmid encoding microRNA-200c ameliorates periodontitis and systemic inflammation in obese mice (2021, Molecular Therapy - Nucleic Acids)
  • Rat Calvarial Bone Regeneration by 3D-Printed β-Tricalcium Phosphate Incorporating MicroRNA-200c (2021, ACS Biomaterials Science & Engineering)

The scientist has frequently collaborated with a group of coauthors, including:

  • Steven Eliason
  • Mason Sweat
  • Dan Su
  • Riley J. Leonard
  • Yan Y. Sweat

Brad A. Amendt has published multiple articles in various scientific journals. The most frequent venues for their publications include:

  • The FASEB Journal
  • Circulation Research
  • Journal of Dental Research
  • Molecular Therapy - Nucleic Acids
  • Molecular Metabolism

Best Publications

  • Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

    Yuerong Zhu;Tsafrira Pe’ery;Junmin Peng;Yegnanarayana Ramanathan

  • Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

    Ge Tao;Peter C. Kahr;Yuka Morikawa;Min Zhang

  • Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors.

    B. A. Amendt;Zhi-Hai Si;C. M. Stoltzfus

  • Differential Regulation of Gene Expression by PITX2 Isoforms

    Carol J. Cox;Herbert M. Espinoza;Bryan McWilliams;Kimberly Chappell

  • Short-chain acyl-coenzyme A dehydrogenase deficiency. Clinical and biochemical studies in two patients.

    B A Amendt;C Greene;L Sweetman;J Cloherty

  • Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1.

    B. A. Amendt;D. Hesslein;Lung-Ji Chang;C. M. Stoltzfus

  • The Molecular Basis of Rieger Syndrome ANALYSIS OF PITX2 HOMEODOMAIN PROTEIN ACTIVITIES

    Brad A. Amendt;Lillian B. Sutherland;Elena V. Semina;Andrew F. Russo

  • The Pitx2 protein in mouse development.

    Tord A. Hjalt;Elena V. Semina;Brad A. Amendt;Jeffrey C. Murray

  • Rieger syndrome: a clinical, molecular, and biochemical analysis.

    B.A. Amendt;E.V. Semina;W.L.M. Alward

  • Multifunctional role of the Pitx2 homeodomain protein C-terminal tail.

    Brad A. Amendt;Lillian B. Sutherland;Andrew F. Russo

  • Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2

    Jinsheng Weng;Jian Luo;Jian Luo;Xuhong Cheng;Chang Jin

  • PITX2, beta-catenin and LEF-1 interact to synergistically regulate the LEF-1 promoter.

    Usha Vadlamudi;Herbert M. Espinoza;Mrudula Ganga;Donna M. Martin

  • Candidate Gene Analyses of Skeletal Variation in Malocclusion

    C.S.G. da Fontoura;S.F. Miller;G.L. Wehby;B.A. Amendt

  • Splicing efficiency of human immunodeficiency virus type 1 tat RNA is determined by both a suboptimal 3' splice site and a 10 nucleotide exon splicing silencer element located within tat exon 2.

    Z.-H. Si;B. A. Amendt;C. M. Stoltzfus

  • Dicarboxylic Aciduria: Deficient [1-14C]Octanoate Oxidation and Medium-Chain Acyl-CoA Dehydrogenase in Fibroblasts

    William J. Rhead;Brad A. Amendt;Kathie S. Fritchman;Sara J. Felts

  • MicroRNAs Regulate Pituitary Development, and MicroRNA 26b Specifically Targets Lymphoid Enhancer Factor 1 (Lef-1), Which Modulates Pituitary Transcription Factor 1 (Pit-1) Expression

    Zichao Zhang;Sergio Florez;Arthur Gutierrez-Hartmann;James F. Martin

  • Pitx2 Regulates Procollagen Lysyl Hydroxylase (Plod) Gene Expression: Implications for the Pathology of Rieger Syndrome

    Tord A. Hjalt;Brad A. Amendt;Jeffrey C. Murray

  • MicroRNAs Play a Critical Role in Tooth Development

    H. Cao;J. Wang;X. Li;S. Florez

  • The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation

    Huojun Cao;Andrew Jheon;Xiao Li;Zhao Sun

  • Aryl Hydrocarbon Receptor Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells

    Shu Zhang;Kyounghyun Kim;Un-Ho Jin;Catherine Pfent

Frequent Co-Authors

James F. Martin
James F. Martin Baylor College of Medicine
Andrew F. Russo
Andrew F. Russo University of Iowa
Jeffrey C. Murray
Jeffrey C. Murray University of Iowa
Elena V. Semina
Elena V. Semina Medical College of Wisconsin
Ophir D. Klein
Ophir D. Klein University of California, San Francisco
Adebowale Adeyemo
Adebowale Adeyemo National Institutes of Health
John F. Engelhardt
John F. Engelhardt University of Iowa
Antonio Baldini
Antonio Baldini University of Naples Federico II
Stephen Safe
Stephen Safe Texas A&M University
Mary L. Marazita
Mary L. Marazita University of Pittsburgh

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