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Immunology

D-Index
63
Citations
10243
World Ranking
3081
National Ranking
1443

Overview

Thomas R. Kozel is affiliated with the University of Nevada Reno in the United States. Their research spans multiple fields, primarily focused on Medicine and Biochemistry, Genetics, and Molecular Biology. Within these broader domains, their work delves into specialized subfields such as Epidemiology, Molecular Biology, Infectious Diseases, Microbiology, and Cell Biology.

Their scholarly output includes publications in various scientific venues. Notable journals where their research has appeared include the Journal of Fungi, Scientific Reports, Medical Mycology, Journal of Clinical Oncology, and mBio.

Thomas R. Kozel's recent research contributions cover a range of topics mainly related to fungal and bacterial infections, diagnostic methods, and treatments. These main topics include:

  • Fungal Infections and Studies
  • Antifungal Resistance and Susceptibility
  • Nail Diseases and Treatments
  • Bacterial Infections and Vaccines
  • Pneumonia and Respiratory Infections
  • Infective Endocarditis Diagnosis and Management
  • Plant Pathogens and Fungal Diseases

Some of their recent papers include:

  • "Antigenic Relatedness between Mannans from Coccidioides immitis and Coccidioides posadasii Spherules and Mycelia" (2024, Journal of Fungi)
  • "Rapid Capsular Antigen Immunoassay for Diagnosis of Inhalational Anthrax: Preclinical Studies and Evaluation in a Nonhuman Primate Model" (2022, mBio)
  • "Tracheal colonization factor A (TcfA) is a biomarker for rapid and specific detection of Bordetella pertussis" (2020, Scientific Reports)
  • "Rapid oxidative release of fungal mannan for detection by immunoassay" (2022, Medical Mycology)
  • "Phase II propensity-matched controlled trial evaluating metformin as an adjunct to neo-adjuvant, concomitant, and adjuvant temozolomide and hypofractionated-accelerated radiotherapy (M-HART) in glioblastoma patients (NCT02780024)" (2025, Journal of Clinical Oncology)

Throughout their work, Kozel has frequently collaborated with other researchers. Frequent coauthors include Amanda R. Burnham-Marusich, Alexander J. Kvam, Kathleen R. Zayac, John N. Galgiani, and Lourdes Lewis.

Best Publications

  • Biosensing with Nanofluidic Diodes

    Ivan Vlassiouk;Thomas R. Kozel;Zuzanna S. Siwy

  • Point-of-Care Testing for Infectious Diseases: Past, Present, and Future.

    Thomas R. Kozel;Amanda R. Burnham-Marusich

  • Characterization of a Murine Monoclonal Antibody to Cryptococcus neoformans Polysaccharide That Is a Candidate for Human Therapeutic Studies

    Arturo Casadevall;Wendy Cleare;Marta Feldmesser;Aharona Glatman-Freedman

  • Evaluation of a Novel Point-of-Care Cryptococcal Antigen Test on Serum, Plasma, and Urine From Patients With HIV-Associated Cryptococcal Meningitis

    JN Jarvis;A Percival;S Bauman;J Pelfrey

  • The capsule of Cryptococcus neoformans passively inhibits phagocytosis of the yeast by macrophages

    T R Kozel;E C Gotschlich

  • Cryptococcus: from human pathogen to model yeast.

    J. Heitman;T. R. Kozel;K. J. Kwon-Chung;J. R. Perfect

  • Purified capsular polysaccharide of Cryptococcus neoformans induces interleukin-10 secretion by human monocytes.

    A Vecchiarelli;C Retini;C Monari;C Tascini

  • Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes.

    A Vecchiarelli;C Retini;D Pietrella;C Monari

  • Complement is essential for protection by an IgM and an IgG3 monoclonal antibody against experimental, hematogenously disseminated candidiasis.

    Yongmoon Han;Thomas R. Kozel;Mason X. Zhang;Randall S. MacGill

  • Activation of the complement system by pathogenic fungi.

    Thomas R. Kozel

  • Inhibition of phagocytosis by cryptococcal polysaccharide: dissociation of the attachment and ingestion phases of phagocytosis.

    T R Kozel;R P Mastroianni

  • Nonencapsulated Variant of Cryptococcus neoformans I. Virulence Studies and Characterization of Soluble Polysaccharide

    Thomas R. Kozel;John Cazin

  • Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils.

    C Retini;A Vecchiarelli;C Monari;C Tascini

  • Passive immunization against Cryptococcus neoformans with an isotype-switch family of monoclonal antibodies reactive with cryptococcal polysaccharide.

    J E Sanford;D M Lupan;A M Schlageter;T R Kozel

  • Molecular architecture of the Cryptococcus neoformans capsule.

    Marcellene A. Gates;Peter Thorkildson;Thomas R. Kozel

  • Large-Scale Evaluation of the Immuno-Mycologics Lateral Flow and Enzyme-Linked Immunoassays for Detection of Cryptococcal Antigen in Serum and Cerebrospinal Fluid

    Jessica Hansen;E. Susan Slechta;Marcellene A. Gates-Hollingsworth;Brandon Neary

  • Activation of C3 and binding to Aspergillus fumigatus conidia and hyphae.

    T R Kozel;M A Wilson;T P Farrell;S M Levitz

  • Role of the capsule in phagocytosis of Cryptococcus neoformans.

    Thomas R. Kozel;Gail S. T. Pfrommer;Ann S. Guerlain;Barbara A. Highison

  • Occurrences, immunoglobulin classes, and biological activities of antibodies in normal human serum that are reactive with Cryptococcus neoformans glucuronoxylomannan.

    D. C. Houpt;G. S. T. Pfrommer;B. J. Young;T. A. Larson

  • Specificity of the thioester-containing reactive site of human C3 and its significance to complement activation.

    A Sahu;T R Kozel;M K Pangburn

  • Immune response to Cryptococcus neoformans soluble polysaccharide: immunological unresponsiveness.

    T R Kozel;W F Gulley;J Cazin

  • mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

    Thomas R. Kozel;William J. Murphy;Suzanne Brandt;Bruce R. Blazar

  • Opsonization of Cryptococcus neoformans by a family of isotype-switch variant antibodies specific for the capsular polysaccharide

    A M Schlageter;T R Kozel

  • Cryptococcus neoformans capsular glucuronoxylomannan induces expression of fas ligand in macrophages.

    Claudia Monari;Eva Pericolini;Giovanni Bistoni;Arturo Casadevall

  • Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans.

    T R Kozel;M A Wilson;J W Murphy

Frequent Co-Authors

Anna Vecchiarelli
Anna Vecchiarelli University of Perugia
Francesco Bistoni
Francesco Bistoni University of Perugia
Arturo Casadevall
Arturo Casadevall Johns Hopkins University
Graeme Meintjes
Graeme Meintjes University of Cape Town
Stuart M. Levitz
Stuart M. Levitz University of Massachusetts Chan Medical School
William J. Murphy
William J. Murphy Texas A&M University
Jim E. Cutler
Jim E. Cutler Louisiana State University
Stephen St. Jeor
Stephen St. Jeor University of Nevada Reno
Richard A. Bowen
Richard A. Bowen Colorado State University
Sharon J. Peacock
Sharon J. Peacock University of Cambridge

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