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Takeshi Uchiumi

Takeshi Uchiumi

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
14428
World Ranking
7528
National Ranking
513

Overview

Takeshi Uchiumi is affiliated with Kyushu University in Japan and has made contributions primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans several subfields, including Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Surgery, and Immunology.

The scientist's work covers diverse topics such as extracellular vesicles in disease, mitochondrial function and pathology, prostate cancer treatment and research, ferroptosis and cancer prognosis, hormonal and reproductive studies, bladder and urothelial cancer treatments, and microRNA in disease regulation.

Frequent coauthors collaborating with Uchiumi include Dongchon Kang, Mikako Yagi, Masaki Shiota, Masatoshi Eto, and Daiki Setoyama.

Publications have appeared often in venues such as Scientific Reports, SSRN Electronic Journal, Life Science Alliance, iScience, and Pediatric Blood & Cancer.

Selected recent publications include:

  • Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss, 2020, Acta Biomaterialia
  • Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression, 2022, Scientific Reports
  • Mitochondrial translation deficiency impairs NAD + -mediated lysosomal acidification, 2021, The EMBO Journal
  • Mitochondrial translation inhibition triggers ATF4 activation, leading to integrated stress response but not to mitochondrial unfolded protein response, 2020, Bioscience Reports
  • Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation, 2022, Oncogenesis

Best Publications

  • The pleiotropic functions of the Y-box-binding protein, YB-1.

    Kimitoshi Kohno;Hiroto Izumi;Takeshi Uchiumi;Megumi Ashizuka

  • Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss.

    Yuki Nakao;Takao Fukuda;Qunzhou Zhang;Terukazu Sanui

  • A Canalicular Multispecific Organic Anion Transporter (cMOAT) Antisense cDNA Enhances Drug Sensitivity in Human Hepatic Cancer Cells

    Koji Koike;Takeshi Kawabe;Toshiya Tanaka;Satoshi Toh

  • Mutations in the Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene, a Novel ABC Transporter, in Patients with Hyperbilirubinemia II/Dubin-Johnson Syndrome

    Morimasa Wada;Satoshi Toh;Ken Taniguchi;Takanori Nakamura

  • Direct Involvement of the Y-box Binding Protein YB-1 in Genotoxic Stress-induced Activation of the Human Multidrug Resistance 1 Gene

    Takefumi Ohga;Takeshi Uchiumi;Yoshinari Makino;Koji Koike

  • Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast

    Yusuke Kurihara;Tomotake Kanki;Yoshimasa Aoki;Yuko Hirota

  • Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome.

    Satoshi Toh;Morimasa Wada;Takeshi Uchiumi;Akihiko Inokuchi

  • NUCLEAR TRANSLOCATION OF THE Y-BOX BINDING PROTEIN BY ULTRAVIOLET IRRADIATION

    Koji Koike;Takeshi Uchiumi;Takefumi Ohga;Satoshi Toh

  • Phosphorylation of Serine 114 on Atg32 mediates mitophagy

    Yoshimasa Aoki;Tomotake Kanki;Yuko Hirota;Yusuke Kurihara

  • Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen.

    Tomoko Ise;Gunji Nagatani;Toshihiro Imamura;Ken Kato

  • Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter

    Zhe Sheng Chen;Takeshi Kawabe;Mayumi Ono;Shunji Aoki;Shunji Aoki

  • Nuclear Expression of the Y-Box Binding Protein, YB-1, as a Novel Marker of Disease Progression in Non-Small Cell Lung Cancer

    Kotaro Shibahara;Kenji Sugio;Kenji Sugio;Toshihiro Osaki;Takeshi Uchiumi

  • Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas.

    Eiji Hinoshita;Takeshi Uchiumi;Ken Ichi Taguchi;Naoko Kinukawa

  • Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression.

    T Okamoto;H Izumi;T Imamura;H Takano

  • Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2).

    Takeshi Kawabe;Zhe Sheng Chen;Morimasa Wada;Takeshi Uchiumi

  • Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.

    Yoko Honda;Fumihiko Ushigome;Noriko Koyabu;Satoshi Morimoto

  • Enhanced coexpression of YB-1 and DNA topoisomerase II α genes in human colorectal carcinomas

    Kazunori Shibao;Hiroshi Takano;Yoshifumi Nakayama;Keisuke Okazaki

  • Human placental transport of vinblastine, vincristine, digoxin and progesterone: contribution of P-glycoprotein.

    Fumihiko Ushigome;Hitomi Takanaga;Hirotami Matsuo;Shigeaki Yanai

  • Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human osteosarcoma.

    Yoshinao Oda;Akio Sakamoto;Norio Shinohara;Takefumi Ohga

  • The role of nuclear Y-box binding protein 1 as a global marker in drug resistance.

    Michihiko Kuwano;Yoshinao Oda;Hiroto Izumi;Song Ju Yang

Frequent Co-Authors

Michihiko Kuwano
Michihiko Kuwano Kyushu University
Dongchon Kang
Dongchon Kang Kyushu University
Kimitoshi Kohno
Kimitoshi Kohno University of Occupational and Environmental Health Japan
Seiji Naito
Seiji Naito Kyushu University
Yoshinao Oda
Yoshinao Oda Kyushu University
Hiroto Izumi
Hiroto Izumi University of Occupational and Environmental Health Japan
Masazumi Tsuneyoshi
Masazumi Tsuneyoshi Kyushu University
Mayumi Ono
Mayumi Ono Kyushu University
Yoshihiko Maehara
Yoshihiko Maehara Kyushu University
Kazuto Nishio
Kazuto Nishio Kindai University

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