What is he best known for?
The fields of study he is best known for:
His primary areas of study are Molecular biology, Cancer research, Transcription factor, Y box binding protein 1 and Angiogenesis.
Hiroto Izumi has researched Molecular biology in several fields, including CAAT box and DNA damage.
His Cancer research research integrates issues from Cell culture, Gene expression, Cancer cell, Immunology and Kinase.
As a member of one scientific family, Hiroto Izumi mostly works in the field of Transcription factor, focusing on Cell biology and, on occasion, Bicarbonate transporter protein, Metastasis and Monocarboxylate transporter.
The Y box binding protein 1 study combines topics in areas such as Regulation of gene expression and DNA repair.
His Angiogenesis research includes themes of Tumor necrosis factor alpha, Basic fibroblast growth factor and Interleukin 8.
His most cited work include:
- Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy (484 citations)
- Induction of Vascular Endothelial Growth Factor by Tumor Necrosis Factor α in Human Glioma Cells POSSIBLE ROLES OF SP-1 (435 citations)
- The pleiotropic functions of the Y-box-binding protein, YB-1. (414 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cancer research, Molecular biology, Pathology, Transcription factor and Internal medicine.
His study in Cancer research is interdisciplinary in nature, drawing from both Cancer cell, Cancer, Cell culture, Gene knockdown and Cell growth.
His biological study spans a wide range of topics, including CAAT box, DNA, DNA damage and Transcription, Gene.
His Pathology study integrates concerns from other disciplines, such as Survival analysis, Lung and Adenocarcinoma.
In his research on the topic of Transcription factor, Transactivation is strongly related with Promoter.
His studies in Internal medicine integrate themes in fields like Endocrinology and Oncology.
He most often published in these fields:
- Cancer research (32.00%)
- Molecular biology (25.14%)
- Pathology (17.14%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (32.00%)
- Lung (11.43%)
- Internal medicine (16.00%)
In recent papers he was focusing on the following fields of study:
Hiroto Izumi mainly investigates Cancer research, Lung, Internal medicine, Pharmacology and Intratracheal instillation.
His Cancer research research incorporates elements of Protein kinase B, Phosphorylation, Gene expression, Cancer cell and Downregulation and upregulation.
His Downregulation and upregulation research focuses on Glioma and how it relates to Cell culture and Cell growth.
His work in the fields of Pulmonary toxicity overlaps with other areas such as Surfactant protein D.
His Internal medicine research includes elements of Gastroenterology, Endocrinology and Antibody.
His research is interdisciplinary, bridging the disciplines of Molecular biology and Gene.
Between 2017 and 2021, his most popular works were:
- Complex consisting of antisense DNA and β-glucan promotes internalization into cell through Dectin-1 and hybridizes with target mRNA in cytosol. (9 citations)
- Targeting Phosphorylation of Y-Box-Binding Protein YBX1 by TAS0612 and Everolimus in Overcoming Antiestrogen Resistance. (5 citations)
- Induction of potent cell growth inhibition by schizophyllan/K-ras antisense complex in combination with gemcitabine (4 citations)
In his most recent research, the most cited papers focused on:
Hiroto Izumi mainly investigates Cancer research, Cell growth, Protein kinase B, Gene silencing and Phosphorylation.
His research in Cancer research intersects with topics in Cancer cell, Internalization and Drug resistance.
His Protein kinase B study incorporates themes from Differentiation-inducing factor, Cell culture, Downregulation and upregulation and Glioma.
Hiroto Izumi interconnects Tamoxifen, Breast cancer, Fulvestrant and Everolimus in the investigation of issues within Phosphorylation.
His Cytoplasm study introduces a deeper knowledge of Cell biology.
He has included themes like Replication protein A, Binding protein, Immunoprecipitation, Ribonucleoprotein and DNA in his Cell biology study.
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