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Biology and Biochemistry

D-Index
66
Citations
14707
World Ranking
8716
National Ranking
587

Overview

Hiroto Izumi is affiliated with the University of Occupational and Environmental Health Japan in Japan. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with significant contributions to multiple subfields including Molecular Biology, Pulmonary and Respiratory Medicine, Health, Toxicology and Mutagenesis, Immunology, and Plant Science.

The focus of their scientific work covers a range of main topics such as:

  • Air Quality and Health Impacts
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Occupational exposure and asthma
  • Microplastics and Plastic Pollution
  • Occupational and environmental lung diseases
  • RNA Interference and Gene Delivery
  • Immune Response and Inflammation

Izumi's frequent publication venues include:

  • Journal of Occupational Health (7 publications)
  • International Journal of Molecular Sciences (6 publications)
  • Scientific Reports (3 publications)
  • Nanomaterials (2 publications)
  • Particle and Fibre Toxicology (2 publications)

Some of the recent papers authored or co-authored by Izumi are:

  • Assessment of Cytokine-Induced Neutrophil Chemoattractants as Biomarkers for Prediction of Pulmonary Toxicity of Nanomaterials, 2020, Nanomaterials
  • YBX2 and cancer testis antigen 45 contribute to stemness, chemoresistance and a high degree of malignancy in human endometrial cancer, 2021, Scientific Reports
  • Investigation of pulmonary inflammatory responses following intratracheal instillation of and inhalation exposure to polypropylene microplastics, 2024, Particle and Fibre Toxicology
  • Predictive Biomarkers for the Ranking of Pulmonary Toxicity of Nanomaterials, 2020, Nanomaterials
  • Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation, 2022, Particle and Fibre Toxicology

Throughout their career, Izumi has worked collaboratively with several frequent co-authors including:

  • Yasuo Morimoto (35 co-authored works)
  • Taisuke Tomonaga (27 co-authored works)
  • Chinatsu Nishida (26 co-authored works)
  • Kazuhiro Yatera (23 co-authored works)
  • Kazuo Sakurai (22 co-authored works)

Best Publications

  • Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis.

    Shigeo Yoshida;Mayumi Ono;Tadahisa Shono;Hiroto Izumi

  • Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy

    Hiroto Izumi;Takayuki Torigoe;Hiroshi Ishiguchi;Hidetaka Uramoto

  • The pleiotropic functions of the Y-box-binding protein, YB-1.

    Kimitoshi Kohno;Hiroto Izumi;Takeshi Uchiumi;Megumi Ashizuka

  • Induction of Vascular Endothelial Growth Factor by Tumor Necrosis Factor α in Human Glioma Cells POSSIBLE ROLES OF SP-1

    Masahiro Ryuto;Mayumi Ono;Hiroto Izumi;Shigeo Yoshida

  • The L45 loop in type I receptors for TGF‐β family members is a critical determinant in specifying Smad isoform activation

    Urban Persson;Hiroto Izumi;Serhiy Souchelnytskyi;Susumu Itoh

  • Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress.

    Tadahisa Shono;Mayumi Ono;Hiroto Izumi;Sei Ichiro Jimi

  • Review of toxicity studies of carbon nanotubes.

    Norihiro Kobayashi;Hiroto Izumi;Yasuo Morimoto

  • Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen.

    Tomoko Ise;Gunji Nagatani;Toshihiro Imamura;Ken Kato

  • P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA.

    Yoichiro Yoshida;Hiroto Izumi;Takayuki Torigoe;Hiroshi Ishiguchi

  • Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells.

    Hiroto Izumi;Mayu Takahashi;Hidetaka Uramoto;Yoshifumi Nakayama

  • Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression.

    T Okamoto;H Izumi;T Imamura;H Takano

  • Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor–Activating Mutations

    Chizuko Yamamoto;Yuji Basaki;Akihiko Kawahara;Kazutaka Nakashima

  • Enhanced coexpression of YB-1 and DNA topoisomerase II α genes in human colorectal carcinomas

    Kazunori Shibao;Hiroshi Takano;Yoshifumi Nakayama;Keisuke Okazaki

  • Twist promotes tumor cell growth through YB-1 expression.

    Masaki Shiota;Hiroto Izumi;Takamitsu Onitsuka;Naoya Miyamoto

  • Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells

    Y Basaki;F Hosoi;F Hosoi;Y Oda;A Fotovati

  • Elevated expression of vacuolar proton pump genes and cellular PH in cisplatin resistance.

    Tadashi Murakami;Izumi Shibuya;Tomoko Ise;Zhe-Sheng Chen

  • The role of nuclear Y-box binding protein 1 as a global marker in drug resistance.

    Michihiko Kuwano;Yoshinao Oda;Hiroto Izumi;Song Ju Yang

  • Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines.

    T Igarashi;H Izumi;T Uchiumi;K Nishio

  • Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis

    Yusuke N. Kimura;Kosuke Watari;Abbas Fotovati;Fumihito Hosoi

  • Y box-binding protein-1 binds preferentially to single-stranded nucleic acids and exhibits 3′→5′ exonuclease activity

    Hiroto Izumi;Toshihiro Imamura;Gunji Nagatani;Tomoko Ise

Frequent Co-Authors

Kimitoshi Kohno
Kimitoshi Kohno University of Occupational and Environmental Health Japan
Michihiko Kuwano
Michihiko Kuwano Kyushu University
Mayumi Ono
Mayumi Ono Kyushu University
Takeshi Uchiumi
Takeshi Uchiumi Kyushu University
Kazuo Sakurai
Kazuo Sakurai The University of Kitakyushu
Kazuto Nishio
Kazuto Nishio Kindai University
Hiroshi Mukae
Hiroshi Mukae Nagasaki University
Seiji Naito
Seiji Naito Kyushu University
Yoshinao Oda
Yoshinao Oda Kyushu University
Yoshiya Tanaka
Yoshiya Tanaka University of Occupational and Environmental Health Japan

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